Nic Enright

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Nicholas Crispen Brett Enright

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Biographical Information[edit]

By the time he made his major league debut in 2025, pitcher Nic Enright was a cancer survivor. For a while, his career path was a normal one: he was first drafted out of high school by the New York Mets in the 2015 amateur draft, but as a 19th rounder, he decided to go to college instead of starting a professional career immediately. He attended Virginia Tech for three years, being redshirted due to an injury in 2017, before being drafted again, this time in the 20th round of the 2019 amateur draft by the Cleveland Indians.

He began his professional career in 2019 with the AZL Indians Blue, giving up just 1 earned run in 18 innings (there were another 5 unearned runs), but then had to sit out the 2020 season when the COVID-19 pandemic shut out the pandemic. He spent time during his forced break working as a cart attendant at a golf course. He resumed playing in 2021 and went 4-4, 3.41 with 5 saves in 34 games between the Class A Lake County Captains and AA Akron Rubber Ducks. He reached AAA in 2023 when he split the season between Akron and the Columbus Clippers of the International League, going 5-1, 2.88 with 11 saves in 48 games. With an organization less flush with pitching talent, he would likely have been added to the 40-man roster at that point, but the now Cleveland Guardians did not have a roster spot available and he was left exposed in the 2022 Rule V Draft, when he was picked by the Miami Marlins.

It was shortly after that that his world collapsed, as he was diagnosed with Hodgkin’s Lymphoma, a form of cancer, after noticing a lump in his neck. He began treatments immediately and they went well enough that he was able to resume pitching in late April, first with the Jupiter Hammerheads of the Florida State League and later with the Jacksonville Jumbo Shrimp of the International League, all the while continuing to undergo rounds of immunotherapy. However, as a Rule V draftee, he needed to be added to the 26-man roster by the Marlins by June 1st, and when they failed to do that, he was returned to Cleveland, where he finished the season with Columbus while continuing his therapy. He ended up a combined 6-2, 4.97 in 34 games. He continued to follow therapy rounds after the season and was declared cancer-free in December, one year after starting treatment. During that time, he received support from Carlos Carrasco, who had made his own successful recovery from cancer a couple of years earlier. It was a more common baseball injury, a shoulder strain, that sidelined him in 2024, costing him four months of action. When he was able to take the mound, he was excellent, however, going 2-1, 1.06 in 16 games for the Clippers. He started the 2025 season on the injured list, recovering from a lat strain, then was activated in late April. He was called up to Cleveland a month later after giving up 2 earned runs in 9 innings for Columbus.

In his major league debut on May 25, 2025, he pitched the final two innings of a 5-0 loss to Tarik Skubal and the Detroit Tigers, giving up 2 hits but no runs and striking out three opponents, including the first batter he faced, Riley Greene. He earned his first career save on August 4th, when he pitched the bottom of the 10th in a 7-6 win over the New York Mets; the Guardians had scored twice in the top of the inning, and while he allowed the ghost runner to cross the plate, that run was unearned.

Further Reading[edit]

  • Bill Ladson: "Enright snares 1st save in 19th career game amid cancer battle", mlb.com, August 5, 2025. [1]
  • Jordan McPherson (Miami Herald): "‘Cancer does not have me’: Miami Marlins reliever announces Hodgkin’s Lymphoma diagnosis", Yahoo! News, February 13, 2023. [2]
  • Tim Stebbins: "In '22, a cancer diagnosis. In '24, a lat injury. In '25? Enright seeks MLB debut", mlb.com, March 11, 2025. [3]
  • Tim Stebbins: "'I can't give up': Enright makes MLB debut 2 1/2 years after cancer diagnosis", mlb.com, May 25, 2025. [4]

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