Andrew Frank Sisco
- Bats Left, Throws Right
- Height 6' 10", Weight 270 lb.
- High School Eastlake High School (Sammamish)
- Debut April 4, 2005
- Fianl Game May 27, 2007
- Born January 13, 1983 in Steamboat Springs, CO USA
After the 2004 season, Sisco was drafted by the Kansas City Royals in the 2004 Rule V Draft. Despite never playing above Class A, he made the Royals' Opening Day roster in 2005 and remained a part of their bullpen for the entire season, going 2-5 with a 3.11 ERA. However, he struggled in 2006, posting a 7.10 ERA in 65 games, and was traded to the Chicago White Sox for Ross Gload following the season.
In 2007, Sisco made the Sox Opening Day roster as a part of the White Sox's bullpen. However, he struggled, going 0-1 with an 8.36 ERA in 19 games in April and May. He spent the remainder of the year with the AAA Charlotte Knights, where he went 3-6 with a 4.35 ERA while primarily a member of the club's starting rotation. He never pitched again in the majors after that.
At 6 feet, 10 inches, Sisco was the tallest man to ever play for the Royals. Chris Young has since matched him.