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| Rk | Mgr | Yrs | From | To | G | W | L | G>.500 | BestFin | WrstFin | AvRk | |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | Ossie Bluege | 5 | 1943 | 1947 | 772 | 375 | 394 | .488 | -19 | 2 | 8 | 4.6 |
| 2 | Donie Bush | 1 | 1923 | 1923 | 155 | 75 | 78 | .490 | -3 | 4 | 4 | 4.0 |
| 3 | Joe Cantillon | 3 | 1907 | 1909 | 465 | 158 | 297 | .347 | -139 | 7 | 8 | 7.7 |
| 4 | Joe Cronin HOF | 2 | 1933 | 1934 | 308 | 165 | 139 | .543 | 26 | 1 | 7 | 4.0 |
| 5 | Patsy Donovan | 1 | 1904 | 1904 | 139 | 37 | 97 | .276 | -60 | 8 | 8 | 8.0 |
| 6 | Chuck Dressen | 3 | 1955 | 1957 | 329 | 116 | 212 | .354 | -96 | 7 | 8 | 7.5 |
| 7 | Cal Ermer | 2 | 1967 | 1968 | 276 | 145 | 129 | .529 | 16 | 2 | 7 | 4.9 |
| 8 | Ron Gardenhire | 12 | 2002 | 2013 | 1850 | 963 | 887 | .521 | 76 | 1 | 5 | 2.2 |
| 9 | Billy Gardner | 5 | 1981 | 1985 | 621 | 268 | 353 | .432 | -85 | 3 | 7 | 5.1 |
| 10 | Johnny Goryl | 2 | 1980 | 1981 | 73 | 34 | 38 | .472 | -4 | 3 | 7 | 5.0 |
| 11 | Clark Griffith HOF | 9 | 1912 | 1920 | 1364 | 693 | 646 | .518 | 47 | 2 | 7 | 4.3 |
| 12 | Bucky Harris HOF | 18 | 1924 | 1954 | 2776 | 1336 | 1416 | .485 | -80 | 1 | 7 | 4.9 |
| 13 | Walter Johnson HOF | 4 | 1929 | 1932 | 617 | 350 | 264 | .570 | 86 | 2 | 5 | 3.2 |
| 14 | Tom Kelly | 16 | 1986 | 2001 | 2385 | 1140 | 1244 | .478 | -104 | 1 | 7 | 3.8 |
| 15 | Malachi Kittridge | 1 | 1904 | 1904 | 18 | 1 | 16 | .059 | -15 | 8 | 8 | 8.0 |
| 16 | Joe Kuhel | 2 | 1948 | 1949 | 308 | 106 | 201 | .345 | -95 | 7 | 8 | 7.5 |
| 17 | Cookie Lavagetto | 5 | 1957 | 1961 | 657 | 271 | 384 | .414 | -113 | 5 | 8 | 7.2 |
| 18 | Tom Loftus | 2 | 1902 | 1903 | 278 | 104 | 169 | .381 | -65 | 6 | 8 | 7.0 |
| 19 | Jim Manning | 1 | 1901 | 1901 | 138 | 61 | 72 | .459 | -11 | 6 | 6 | 6.0 |
| 20 | Billy Martin | 1 | 1969 | 1969 | 162 | 97 | 65 | .599 | 32 | 1 | 1 | 1.0 |
| 21 | Gene Mauch | 5 | 1976 | 1980 | 772 | 378 | 394 | .490 | -16 | 3 | 4 | 3.6 |
| 22 | Jimmy McAleer | 2 | 1910 | 1911 | 311 | 130 | 175 | .426 | -45 | 7 | 7 | 7.0 |
| 23 | George McBride | 1 | 1921 | 1921 | 154 | 80 | 73 | .523 | 7 | 4 | 4 | 4.0 |
| 24 | Sam Mele | 7 | 1961 | 1967 | 963 | 524 | 436 | .546 | 88 | 1 | 7 | 3.2 |
| 25 | Clyde Milan | 1 | 1922 | 1922 | 154 | 69 | 85 | .448 | -16 | 6 | 6 | 6.0 |
| 26 | Ray Miller | 2 | 1985 | 1986 | 239 | 109 | 130 | .456 | -21 | 4 | 6 | 5.2 |
| 27 | Frank Quilici | 4 | 1972 | 1975 | 568 | 280 | 287 | .494 | -7 | 3 | 4 | 3.3 |
| 28 | Bill Rigney | 3 | 1970 | 1972 | 392 | 208 | 184 | .531 | 24 | 1 | 5 | 3.0 |
| 29 | Jake Stahl | 2 | 1905 | 1906 | 305 | 119 | 182 | .395 | -63 | 7 | 7 | 7.0 |