- Bats Left, Throws Right
- Height 6' 4", Weight 220 lb.
- School Harvard University
- High School Montclair Kimberley Academy
- Debut June 4, 2010
Herrmann made his major league debut in 2010, pitching 40 times for the Indians as a reliever, with a record of 0-1, 4.03 and 1 save. He had brilliant with the AAA Columbus Clippers before getting the call, putting up an ERA of 0.31 in 28 2/3 innings. In 2011, he went 4-0 but with a 5.11 ERA for the Tribe, pitching another 40 games in relief. He pitched another 9 times for Columbus, but his ERA was 5.91. As a result of his struggles the previous season, he started 2012 back with Columbus, and did not make it back to Cleveland until August. He went 2-2, 4.78 in 42 games for the Clippers, and then had no record but a solid 2.33 ERA in 15 games for Cleveland.
Herrmann headed into spring training in 2013 with the objective of making the Indians' starting rotation, a change of usage for a pitcher who had last started a game in 2009 in the minors. He did have significant prior experience in the role before that, however, having been a full-time starter from 2006 to 2008, including putting up back-to-back seasons of 11 wins for the Kinston Indians in 2007 and the AA Akron Aeros in 2008. However, his plans were quickly thwarted as he fell victim to a sprained ligament in his right elbow, the sort of injury that could cause him to miss the entire season if surgery was deemed to be necessary.
- Justice B. Hill: "Down On The Farm: Frank Herrmann Harvard-Bred Pitching Prospect Ditches Books For Baseball", in MLB.com, May 20, 2008. 
- Tim Leonard: "From Harvard To N. Carolina - Herrmann Continues His Journey", in The Record (Bergen County, NJ), July 29, 2007. 
- Pablo S. Torre and Alex McPhillips: "Two For The Show: Zak Farkes And Frank Herrmann Sign Professional Contracts As Free Agents", in The Harvard Crimson, September 14, 2005.