MLB Scores and Standings Thursday, September 22, 2022
| Los Angeles Angels | 3 | Final |
| Texas Rangers | 5 |
| W | Matt Moore (5-2) |
| L | José Quijada (0-5) |
| S | José Leclerc (7) |
| Minnesota Twins | 1 | Final |
| Kansas City Royals | 4 |
| W | Jonathan Heasley (4-8) |
| L | Josh Winder (4-5) |
| S | Brad Keller (1) |
| San Francisco Giants | 3 | Final |
| Colorado Rockies | 0 |
| W | Jharel Cotton (3-2) |
| L | José Ureña (3-7) |
| S | Camilo Doval (24) |
| Seattle Mariners | 9 | Final |
| Oakland Athletics | 5 |
| W | Matthew Boyd (2-0) |
| L | Kirby Snead (1-1) |
| St. Louis Cardinals | 5 | Final |
| San Diego Padres | 4 |
| W | Jack Flaherty (1-1) |
| L | Nick Martinez (4-4) |
| S | Giovanny Gallegos (14) |
| Chicago Cubs | 3 | Final |
| Pittsburgh Pirates | 2 |
| W | Hayden Wesneski (2-1) |
| L | Mitch Keller (5-12) |
| S | Mark Leiter Jr. (3) |
| Milwaukee Brewers | 5 | Final |
| Cincinnati Reds | 1 |
| W | Brandon Woodruff (12-4) |
| L | Hunter Greene (4-13) |
| Toronto Blue Jays | 5 | Final |
| Tampa Bay Rays | 10 |
| W | Ryan Yarbrough (3-8) |
| L | JosĂ© BerrĂos (11-6) |
| Houston Astros | 0 | Final |
| Baltimore Orioles | 2 |
| W | Kyle Bradish (4-7) |
| L | Justin Verlander (17-4) |
| S | Félix Bautista (15) |
| Boston Red Sox | 4 | Final |
| New York Yankees | 5 | (10) |
| W | Clay Holmes (7-4) |
| L | Kaleb Ort (1-2) |
| Atlanta Braves | 0 | Final |
| Philadelphia Phillies | 1 |
| W | Ranger Suarez (10-5) |
| L | Max Fried (13-7) |
| S | José Alvarado (2) |
| Cleveland Guardians | 4 | Final |
| Chicago White Sox | 2 |
| W | Shane Bieber (12-8) |
| L | Johnny Cueto (7-9) |
| S | Emmanuel Clase (37) |
| Arizona Diamondbacks | 2 | Final |
| Los Angeles Dodgers | 3 |
| W | Craig Kimbrel (6-6) |
| L | Reyes Moronta (1-1) |
Standings Up to and Including this Date
AL East Division
AL Central Division
AL West Division
NL East Division
NL Central Division
AL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| HOU | 99 | 52 | .656 | -- | 687 | 478 | .660 |
| NYY | 91 | 58 | .611 | 7.0 | 756 | 533 | .655 |
| TOR | 84 | 66 | .560 | 14.5 | 712 | 642 | .547 |
| CLE | 83 | 67 | .553 | 15.5 | 639 | 592 | .535 |
| TBR | 83 | 67 | .553 | 15.5 | 631 | 565 | .550 |
| SEA | 82 | 67 | .550 | 16.0 | 624 | 553 | .555 |
| BAL | 78 | 71 | .523 | 20.0 | 616 | 618 | .499 |
| CHW | 76 | 74 | .507 | 22.5 | 653 | 664 | .492 |
| MIN | 73 | 77 | .487 | 25.5 | 642 | 638 | .503 |
| BOS | 72 | 77 | .483 | 26.0 | 678 | 715 | .476 |
| TEX | 65 | 84 | .436 | 33.0 | 665 | 683 | .488 |
| LAA | 65 | 85 | .433 | 33.5 | 571 | 633 | .453 |
| KCR | 61 | 89 | .407 | 37.5 | 585 | 745 | .391 |
| DET | 57 | 92 | .383 | 41.0 | 497 | 665 | .370 |
| OAK | 55 | 95 | .367 | 43.5 | 524 | 715 | .362 |
NL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| LAD | 104 | 46 | .693 | -- | 802 | 476 | .722 |
| NYM | 95 | 56 | .629 | 9.5 | 709 | 562 | .605 |
| ATL | 93 | 57 | .620 | 11.0 | 731 | 561 | .619 |
| STL | 88 | 63 | .583 | 16.5 | 718 | 594 | .586 |
| SDP | 83 | 67 | .553 | 21.0 | 653 | 617 | .526 |
| PHI | 82 | 67 | .550 | 21.5 | 695 | 632 | .543 |
| MIL | 80 | 70 | .533 | 24.0 | 682 | 653 | .520 |
| SFG | 73 | 77 | .487 | 31.0 | 656 | 647 | .506 |
| ARI | 70 | 81 | .464 | 34.5 | 659 | 688 | .480 |
| CHC | 65 | 85 | .433 | 39.0 | 601 | 703 | .429 |
| COL | 64 | 86 | .427 | 40.0 | 659 | 805 | .409 |
| MIA | 61 | 89 | .407 | 43.0 | 537 | 638 | .422 |
| CIN | 59 | 91 | .393 | 45.0 | 623 | 749 | .417 |
| PIT | 55 | 95 | .367 | 49.0 | 535 | 763 | .343 |
| WSN | 52 | 97 | .349 | 51.5 | 568 | 781 | .358 |


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