MLB Scores and Standings Thursday, September 23, 2021
| Chicago White Sox | 7 | Final |
| Cleveland Indians | 2 | (7) |
| W | Aaron Bummer (4-5) |
| L | Aaron Civale (11-5) |
| St. Louis Cardinals | 8 | Final |
| Milwaukee Brewers | 5 |
| W | T.J. McFarland (4-1) |
| L | Aaron Ashby (3-1) |
| S | Giovanny Gallegos (12) |
| Los Angeles Dodgers | 7 | Final |
| Colorado Rockies | 5 | (10) |
| W | Kenley Jansen (4-4) |
| L | Lucas Gilbreath (2-2) |
| S | Blake Treinen (6) |
| Seattle Mariners | 6 | Final |
| Oakland Athletics | 5 |
| W | Joe Smith (3-4) |
| L | Jake Diekman (3-3) |
| S | Paul Sewald (10) |
| Atlanta Braves | 4 | Final |
| Arizona Diamondbacks | 6 |
| W | Sean Poppen (1-0) |
| L | Jacob Webb (5-4) |
| S | J.B. Wendelken (2) |
| San Francisco Giants | 6 | Final |
| San Diego Padres | 7 | (10) |
| W | Ross Detwiler (3-1) |
| L | Dominic Leone (3-5) |
| Chicago White Sox | 3 | Final |
| Cleveland Indians | 5 | (7) |
| W | Emmanuel Clase (4-5) |
| L | José Ruiz (1-3) |
| Washington Nationals | 3 | Final |
| Cincinnati Reds | 2 |
| W | Patrick Corbin (9-15) |
| L | Luis Castillo (8-16) |
| S | Kyle Finnegan (11) |
| Texas Rangers | 0 | Final |
| Baltimore Orioles | 3 |
| W | Zac Lowther (1-2) |
| L | Glenn Otto (0-3) |
| S | Tyler Wells (4) |
| Pittsburgh Pirates | 6 | Final |
| Philadelphia Phillies | 12 |
| W | Aaron Nola (9-8) |
| L | Anthony Banda (2-2) |
| Toronto Blue Jays | 2 | Final |
| Minnesota Twins | 7 |
| W | Michael Pineda (8-8) |
| L | Thomas Hatch (0-1) |
| S | Ralph Garza (1) |
| Houston Astros | 2 | Final |
| Los Angeles Angels | 3 |
| W | Austin Warren (2-0) |
| L | Lance McCullers Jr. (12-5) |
| S | Raisel Iglesias (33) |
Standings Up to and Including this Date
AL East Division
AL Central Division
AL West Division
NL East Division
NL Central Division
AL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| TBR | 94 | 59 | .614 | -- | 811 | 633 | .611 |
| HOU | 91 | 62 | .595 | 3.0 | 827 | 608 | .637 |
| BOS | 88 | 65 | .575 | 6.0 | 794 | 710 | .551 |
| NYY | 86 | 67 | .562 | 8.0 | 668 | 634 | .524 |
| CHW | 86 | 67 | .562 | 8.0 | 754 | 609 | .596 |
| TOR | 85 | 68 | .556 | 9.0 | 796 | 630 | .605 |
| SEA | 84 | 69 | .549 | 10.0 | 654 | 707 | .464 |
| OAK | 82 | 71 | .536 | 12.0 | 697 | 637 | .541 |
| CLE | 75 | 77 | .493 | 18.5 | 669 | 688 | .487 |
| DET | 74 | 78 | .487 | 19.5 | 659 | 712 | .465 |
| LAA | 73 | 80 | .477 | 21.0 | 675 | 768 | .441 |
| KCR | 69 | 83 | .454 | 24.5 | 646 | 741 | .438 |
| MIN | 68 | 85 | .444 | 26.0 | 691 | 794 | .437 |
| TEX | 55 | 98 | .359 | 39.0 | 581 | 771 | .373 |
| BAL | 49 | 104 | .320 | 45.0 | 628 | 901 | .341 |
NL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| SFG | 99 | 54 | .647 | -- | 756 | 573 | .624 |
| LAD | 98 | 55 | .641 | 1.0 | 774 | 527 | .669 |
| MIL | 91 | 62 | .595 | 8.0 | 702 | 581 | .586 |
| STL | 83 | 69 | .546 | 15.5 | 653 | 635 | .513 |
| ATL | 80 | 72 | .526 | 18.5 | 744 | 630 | .576 |
| PHI | 79 | 74 | .516 | 20.0 | 707 | 711 | .497 |
| SDP | 78 | 75 | .510 | 21.0 | 698 | 653 | .530 |
| CIN | 78 | 75 | .510 | 21.0 | 733 | 711 | .514 |
| NYM | 73 | 79 | .480 | 25.5 | 600 | 630 | .478 |
| COL | 71 | 81 | .467 | 27.5 | 701 | 742 | .474 |
| CHC | 67 | 85 | .441 | 31.5 | 659 | 786 | .420 |
| MIA | 64 | 88 | .421 | 34.5 | 601 | 652 | .463 |
| WSN | 64 | 89 | .418 | 35.0 | 688 | 763 | .453 |
| PIT | 57 | 95 | .375 | 41.5 | 566 | 777 | .359 |
| ARI | 49 | 104 | .320 | 50.0 | 639 | 857 | .369 |


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