MLB Scores and Standings Tuesday, September 21, 2021
| Chicago White Sox | 3 | Final |
| Detroit Tigers | 5 |
| W | Bryan Garcia (3-2) |
| L | Jace Fry (0-1) |
| S | Michael Fulmer (11) |
| Kansas City Royals | 1 | Final |
| Cleveland Indians | 4 |
| W | Cal Quantrill (7-3) |
| L | Daniel Lynch IV (4-6) |
| S | Emmanuel Clase (24) |
| Pittsburgh Pirates | 6 | Final |
| Cincinnati Reds | 2 |
| W | Mitch Keller (5-11) |
| L | Tyler Mahle (12-6) |
| Washington Nationals | 7 | Final |
| Miami Marlins | 1 |
| W | Josh Rogers (2-0) |
| L | Trevor Rogers (7-8) |
| Texas Rangers | 1 | Final |
| New York Yankees | 7 |
| W | Jordan Montgomery (6-6) |
| L | Dane Dunning (5-9) |
| Baltimore Orioles | 2 | Final |
| Philadelphia Phillies | 3 | (10) |
| W | Ian Kennedy (3-1) |
| L | César Valdez (2-2) |
| New York Mets | 3 | Final |
| Boston Red Sox | 6 |
| W | Ryan Brasier (1-1) |
| L | Marcus Stroman (9-13) |
| Toronto Blue Jays | 4 | Final |
| Tampa Bay Rays | 2 |
| W | Alek Manoah (7-2) |
| L | Nick Anderson (0-1) |
| S | Jordan Romano (20) |
| Minnesota Twins | 9 | Final |
| Chicago Cubs | 5 |
| W | Kyle Barraclough (2-0) |
| L | Alec Mills (6-7) |
| St. Louis Cardinals | 2 | Final |
| Milwaukee Brewers | 1 |
| W | Jake Woodford (3-3) |
| L | Brandon Woodruff (9-10) |
| S | Giovanny Gallegos (11) |
| Los Angeles Dodgers | 5 | Final |
| Colorado Rockies | 4 | (10) |
| W | Kenley Jansen (3-4) |
| L | Jhoulys ChacĂn (3-2) |
| S | Alex Vesia (1) |
| Houston Astros | 10 | Final |
| Los Angeles Angels | 5 |
| W | José Urquidy (8-3) |
| L | Packy Naughton (0-3) |
| Atlanta Braves | 6 | Final |
| Arizona Diamondbacks | 1 |
| W | Drew Smyly (10-4) |
| L | Luke Weaver (3-6) |
| Seattle Mariners | 5 | Final |
| Oakland Athletics | 2 |
| W | Marco Gonzales (9-5) |
| L | Paul Blackburn (1-3) |
| S | Drew Steckenrider (10) |
| San Francisco Giants | 6 | Final |
| San Diego Padres | 5 |
| W | Tony Watson (6-4) |
| L | Mark Melancon (4-3) |
| S | Tyler Rogers (13) |
Standings Up to and Including this Date
AL East Division
AL Central Division
AL West Division
NL East Division
NL Central Division
AL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| TBR | 93 | 59 | .612 | -- | 804 | 632 | .608 |
| HOU | 90 | 61 | .596 | 2.5 | 816 | 600 | .637 |
| BOS | 87 | 65 | .572 | 6.0 | 782 | 705 | .547 |
| TOR | 85 | 66 | .563 | 7.5 | 793 | 616 | .614 |
| CHW | 85 | 66 | .563 | 7.5 | 744 | 602 | .596 |
| NYY | 85 | 67 | .559 | 8.0 | 661 | 631 | .521 |
| SEA | 82 | 69 | .543 | 10.5 | 644 | 701 | .461 |
| OAK | 82 | 69 | .543 | 10.5 | 691 | 627 | .544 |
| CLE | 74 | 76 | .493 | 18.0 | 662 | 678 | .489 |
| DET | 74 | 78 | .487 | 19.0 | 659 | 712 | .465 |
| LAA | 72 | 79 | .477 | 20.5 | 667 | 757 | .442 |
| KCR | 69 | 83 | .454 | 24.0 | 646 | 741 | .438 |
| MIN | 66 | 85 | .437 | 26.5 | 679 | 788 | .432 |
| TEX | 55 | 96 | .364 | 37.5 | 578 | 761 | .377 |
| BAL | 48 | 103 | .318 | 44.5 | 622 | 897 | .338 |
NL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| SFG | 98 | 53 | .649 | -- | 742 | 560 | .626 |
| LAD | 97 | 54 | .642 | 1.0 | 762 | 512 | .674 |
| MIL | 91 | 60 | .603 | 7.0 | 695 | 563 | .595 |
| STL | 81 | 69 | .540 | 16.5 | 635 | 628 | .505 |
| ATL | 79 | 71 | .527 | 18.5 | 731 | 622 | .573 |
| CIN | 78 | 74 | .513 | 20.5 | 731 | 708 | .515 |
| PHI | 77 | 74 | .510 | 21.0 | 691 | 702 | .493 |
| SDP | 77 | 74 | .510 | 21.0 | 685 | 639 | .532 |
| NYM | 73 | 78 | .483 | 25.0 | 595 | 618 | .483 |
| COL | 70 | 80 | .467 | 27.5 | 686 | 730 | .472 |
| CHC | 67 | 84 | .444 | 31.0 | 655 | 781 | .420 |
| MIA | 64 | 87 | .424 | 34.0 | 596 | 645 | .464 |
| WSN | 62 | 89 | .411 | 36.0 | 678 | 756 | .450 |
| PIT | 57 | 94 | .377 | 41.0 | 560 | 765 | .361 |
| ARI | 48 | 103 | .318 | 50.0 | 631 | 844 | .370 |


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