MLB Scores and Standings Friday, April 21, 2006
| Minnesota Twins | 1 | Final |
| Chicago White Sox | 7 |
| W | Mark Buehrle (3-0) |
| L | Johan Santana (0-3) |
| San Francisco Giants | 8 | Final |
| Colorado Rockies | 9 |
| W | David Cortés (2-0) |
| L | Tim Worrell (2-1) |
| Pittsburgh Pirates | 2 | Final |
| Houston Astros | 3 |
| W | Wandy Rodríguez (3-0) |
| L | Zach Duke (1-2) |
| S | Brad Lidge (6) |
| Cleveland Indians | 6 | Final |
| Kansas City Royals | 5 |
| W | Danny Graves (2-0) |
| L | Elmer Dessens (1-1) |
| S | Bob Wickman (4) |
| Arizona Diamondbacks | 3 | Final |
| Los Angeles Dodgers | 6 |
| W | Odalis Pérez (3-0) |
| L | Orlando Hernández (1-3) |
| S | Danys Báez (4) |
| Cincinnati Reds | 3 | Final |
| Milwaukee Brewers | 1 |
| W | Bronson Arroyo (3-0) |
| L | Ben Sheets (0-2) |
| S | David Weathers (4) |
| Baltimore Orioles | 6 | Final |
| New York Yankees | 5 |
| W | Kris Benson (2-2) |
| L | Chien-Ming Wang (1-1) |
| S | Chris Ray (6) |
| LA Angels of Anaheim | 3 | Final |
| Oakland Athletics | 5 |
| W | Rich Harden (3-0) |
| L | J.C. Romero (1-2) |
| S | Kiko Calero (1) |
| Florida Marlins | 4 | Final |
| Philadelphia Phillies | 3 |
| W | Scott Olsen (1-1) |
| L | Jon Lieber (0-4) |
| S | Joe Borowski (2) |
| New York Mets | 1 | Final |
| San Diego Padres | 2 | (14) |
| W | Brian Sweeney (1-0) |
| L | Chad Bradford (0-1) |
| Detroit Tigers | 2 | Final |
| Seattle Mariners | 1 |
| W | Mike Maroth (3-0) |
| L | Jarrod Washburn (1-3) |
| S | Todd Jones (1) |
| Chicago Cubs | 3 | Final |
| St. Louis Cardinals | 9 |
| W | Mark Mulder (2-0) |
| L | Jerome Williams (0-2) |
| Tampa Bay Devil Rays | 7 | Final |
| Texas Rangers | 13 |
| W | C.J. Wilson (1-0) |
| L | Seth McClung (1-3) |
| Boston Red Sox | 6 | Final |
| Toronto Blue Jays | 7 | (12) |
| W | Justin Speier (1-0) |
| L | Keith Foulke (0-1) |
| Atlanta Braves | 3 | Final |
| Washington Nationals | 7 |
| W | Mike Stanton (1-2) |
| L | Lance Cormier (0-1) |
Standings Up to and Including this Date
AL East Division
AL Central Division
AL West Division
NL East Division
NL Central Division
AL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| CHW | 11 | 5 | .688 | -- | 91 | 68 | .630 |
| BOS | 11 | 6 | .647 | 0.5 | 83 | 72 | .565 |
| BAL | 11 | 7 | .611 | 1.0 | 109 | 104 | .521 |
| CLE | 10 | 7 | .588 | 1.5 | 108 | 91 | .578 |
| DET | 10 | 7 | .588 | 1.5 | 87 | 69 | .604 |
| TOR | 8 | 7 | .533 | 2.5 | 90 | 83 | .537 |
| OAK | 8 | 9 | .471 | 3.5 | 71 | 89 | .398 |
| TEX | 8 | 9 | .471 | 3.5 | 89 | 85 | .521 |
| TBD | 8 | 9 | .471 | 3.5 | 90 | 107 | .421 |
| LAA | 8 | 9 | .471 | 3.5 | 83 | 89 | .468 |
| NYY | 7 | 8 | .467 | 3.5 | 93 | 69 | .633 |
| MIN | 7 | 9 | .438 | 4.0 | 81 | 92 | .442 |
| SEA | 7 | 11 | .389 | 5.0 | 84 | 87 | .484 |
| KCR | 2 | 13 | .133 | 8.5 | 51 | 105 | .211 |
NL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| HOU | 11 | 5 | .688 | -- | 91 | 79 | .564 |
| NYM | 11 | 5 | .688 | -- | 82 | 57 | .660 |
| CIN | 11 | 6 | .647 | 0.5 | 110 | 103 | .530 |
| STL | 10 | 6 | .625 | 1.0 | 81 | 64 | .606 |
| CHC | 9 | 6 | .600 | 1.5 | 79 | 67 | .575 |
| COL | 9 | 7 | .563 | 2.0 | 93 | 88 | .525 |
| SFG | 9 | 7 | .563 | 2.0 | 78 | 93 | .420 |
| ATL | 8 | 9 | .471 | 3.5 | 94 | 91 | .515 |
| MIL | 8 | 9 | .471 | 3.5 | 83 | 91 | .458 |
| LAD | 8 | 9 | .471 | 3.5 | 86 | 77 | .550 |
| SDP | 7 | 9 | .438 | 4.0 | 69 | 77 | .450 |
| ARI | 7 | 10 | .412 | 4.5 | 89 | 84 | .526 |
| WSN | 7 | 10 | .412 | 4.5 | 87 | 95 | .460 |
| PHI | 6 | 10 | .375 | 5.0 | 72 | 99 | .358 |
| FLA | 5 | 10 | .333 | 5.5 | 71 | 78 | .457 |
| PIT | 5 | 13 | .278 | 7.0 | 84 | 106 | .395 |
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