MLB Scores and Standings Monday, April 21, 1980
| Chicago White Sox | 8 | Final |
| Boston Red Sox | 9 |
| W | Skip Lockwood (1-1) |
| L | Randy Scarbery (0-1) |
| S | Dick Drago (1) |
| Cincinnati Reds | 6 | Final |
| Houston Astros | 5 |
| W | Mike LaCoss (3-0) |
| L | Vern Ruhle (0-1) |
| S | Tom Hume (3) |
| Toronto Blue Jays | 7 | Final |
| Kansas City Royals | 1 |
| W | Dave Stieb (2-0) |
| L | Rich Gale (0-2) |
| San Francisco Giants | 3 | Final |
| Los Angeles Dodgers | 4 |
| W | Burt Hooton (2-1) |
| L | Vida Blue (2-1) |
| S | Steve Howe (1) |
| Cleveland Indians | 5 | Final |
| Milwaukee Brewers | 7 | (11) |
| W | Bob McClure (1-0) |
| L | VĂctor Cruz (0-2) |
| Pittsburgh Pirates | 7 | Final |
| Montreal Expos | 1 |
| W | John Candelaria (1-1) |
| L | Ross Grimsley (0-1) |
| Baltimore Orioles | 2 | Final |
| New York Yankees | 3 |
| W | Tommy John (2-0) |
| L | Mike Flanagan (1-2) |
| S | Rich Gossage (1) |
| New York Mets | 3 | Final |
| Philadelphia Phillies | 0 |
| W | Ray Burris (2-1) |
| L | Steve Carlton (2-1) |
| S | Neil Allen (4) |
| Oakland Athletics | 4 | Final |
| Seattle Mariners | 2 |
| W | Jeff Jones (1-0) |
| L | Shane Rawley (0-1) |
| Detroit Tigers | 2 | Final |
| Texas Rangers | 3 |
| W | Jon Matlack (2-0) |
| L | Milt Wilcox (0-1) |
| S | Sparky Lyle (2) |
Standings Up to and Including this Date
AL East Division
AL West Division
NL East Division
AL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| OAK | 9 | 3 | .750 | -- | 58 | 36 | .705 |
| TEX | 8 | 3 | .727 | 0.5 | 58 | 48 | .586 |
| CHW | 7 | 4 | .636 | 1.5 | 60 | 52 | .565 |
| BOS | 6 | 4 | .600 | 2.0 | 47 | 69 | .331 |
| TOR | 5 | 4 | .556 | 2.5 | 44 | 37 | .579 |
| MIL | 5 | 4 | .556 | 2.5 | 50 | 38 | .623 |
| SEA | 7 | 6 | .538 | 2.5 | 52 | 60 | .435 |
| BAL | 5 | 6 | .455 | 3.5 | 49 | 48 | .509 |
| NYY | 5 | 6 | .455 | 3.5 | 54 | 45 | .583 |
| KCR | 5 | 6 | .455 | 3.5 | 46 | 59 | .388 |
| MIN | 5 | 7 | .417 | 4.0 | 41 | 36 | .559 |
| CAL | 4 | 6 | .400 | 4.0 | 34 | 37 | .461 |
| CLE | 2 | 7 | .222 | 5.5 | 34 | 50 | .331 |
| DET | 2 | 9 | .182 | 6.5 | 49 | 61 | .401 |
NL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| CIN | 11 | 1 | .917 | -- | 65 | 28 | .824 |
| PIT | 7 | 3 | .700 | 3.0 | 54 | 38 | .655 |
| HOU | 7 | 4 | .636 | 3.5 | 53 | 42 | .605 |
| CHC | 5 | 3 | .625 | 4.0 | 41 | 36 | .559 |
| SDP | 6 | 5 | .545 | 4.5 | 40 | 45 | .446 |
| MON | 4 | 5 | .444 | 5.5 | 38 | 53 | .352 |
| PHI | 4 | 5 | .444 | 5.5 | 50 | 41 | .590 |
| LAD | 5 | 7 | .417 | 6.0 | 50 | 55 | .457 |
| NYM | 4 | 6 | .400 | 6.0 | 40 | 46 | .436 |
| STL | 4 | 6 | .400 | 6.0 | 43 | 52 | .414 |
| SFG | 4 | 8 | .333 | 7.0 | 43 | 48 | .450 |
| ATL | 1 | 9 | .100 | 9.0 | 18 | 51 | .129 |


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