MLB Probable Pitchers for Wednesday, September 27, 2017
| Astros (97-60) | Preview | |
| Rangers (76-81) | 2:05PM |
| HOU | Justin Verlander (#35, 34, RHP, 14-8, 3.38) |
| TEX | Nick Martinez (#22, 26, RHP, 3-7, 5.42) |
| Marlins (74-83) | Preview | |
| Rockies (85-73) | 3:10PM |
| MIA | Adam Conley (#61, 27, LHP, 7-7, 5.74) |
| COL | Jon Gray (#55, 25, RHP, 9-4, 3.62) |
| Mariners (77-81) | Preview | |
| Athletics (72-85) | 3:35PM |
| SEA | Erasmo Ramirez (#31, 27, RHP, 5-6, 4.35) |
| OAK | Kendall Graveman (#49, 26, RHP, 6-4, 4.17) |
| Giants (62-96) | Preview | |
| D'backs (91-67) | 3:40PM |
| SFG | Jeff Samardzija (#29, 32, RHP, 9-15, 4.51) |
| ARI | Braden Shipley (#34, 25, RHP, 0-1, 5.40) |
| Orioles (75-83) | Preview | |
| Pirates (72-85) | 7:05PM |
| BAL | Gabriel Ynoa (#49, 24, RHP, 2-2, 3.41) |
| PIT | Chad Kuhl (#39, 24, RHP, 7-11, 4.31) |
| Nationals (95-62) | Preview | |
| Phillies (63-95) | 7:05PM |
| WSN | Tanner Roark (#57, 30, RHP, 13-10, 4.41) |
| PHI | Mark Leiter (#59, 26, RHP, 3-6, 4.69) |
| Rays (76-81) | Preview | |
| Yankees (88-69) | 7:05PM |
| TBR | Matt Andriese (#35, 27, RHP, 5-4, 4.44) |
| NYY | Luis Severino (#40, 23, RHP, 13-6, 3.03) |
| Cubs (88-69) | Preview | |
| Cardinals (82-75) | 7:08PM |
| CHC | John Lackey (#41, 38, RHP, 11-11, 4.67) |
| STL | Michael Wacha (#52, 25, RHP, 12-8, 4.00) |
| Twins (83-74) | Preview | |
| Indians (98-59) | 7:10PM |
| MIN | Adalberto Mejia (#49, 24, LHP, 4-6, 4.48) |
| CLE | Danny Salazar (#31, 27, RHP, 5-6, 4.48) |
| Blue Jays (75-83) | Preview | |
| Red Sox (91-66) | 7:10PM |
| TOR | Marco Estrada (#25, 33, RHP, 10-8, 4.70) |
| BOS | Rick Porcello (#22, 28, RHP, 10-17, 4.55) |
| Braves (71-86) | Preview | |
| Mets (68-90) | 7:10PM |
| ATL | Sean Newcomb (#51, 24, LHP, 4-8, 4.26) |
| NYM | Robert Gsellman (#65, 23, RHP, 7-7, 5.38) |
| Angels (78-79) | Preview | |
| White Sox (64-93) | 8:10PM |
| LAA | Garrett Richards (#43, 29, RHP, 0-2, 1.50) |
| CHW | Reynaldo Lopez (#40, 23, RHP, 3-3, 4.54) |
| Reds (66-91) | Preview | |
| Brewers (83-74) | 8:10PM |
| CIN | Homer Bailey (#34, 31, RHP, 5-9, 6.96) |
| MIL | Brandon Woodruff (#53, 24, RHP, 2-2, 3.76) |
| Tigers (62-95) | Preview | |
| Royals (77-80) | 8:15PM |
| DET | Jordan Zimmermann (#27, 31, RHP, 8-13, 6.19) |
| KCR | Jason Hammel (#39, 34, RHP, 8-13, 5.32) |
| Padres (70-88) | Preview | |
| Dodgers (101-57) | 10:10PM |
| SDP | Clayton Richard (#3, 33, LHP, 8-14, 4.63) |
| LAD | Rich Hill (#44, 37, LHP, 11-8, 3.50) |
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