Single-Season Leaders & Records for Strikeouts per 9 IP
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| Rank | Player (age that year) | Strikeouts per 9 IP | Year | Throws |
|---|---|---|---|---|
| 1. | Shane Bieber (25) | 14.1983 | 2020 | R |
| 2. | Gerrit Cole (28) | 13.8179 | 2019 | R |
| 3. | Jacob deGrom (32) | 13.7647 | 2020 | R |
| 4. | Randy Johnson+ (37) | 13.4099 | 2001 | L |
| 5. | Pedro Martinez+ (27) | 13.2047 | 1999 | R |
| 6. | Chris Sale (28) | 12.9331 | 2017 | L |
| 7. | Max Scherzer (34) | 12.6905 | 2019 | R |
| 8. | Kerry Wood (21) | 12.5820 | 1998 | R |
| 9. | Randy Johnson+ (36) | 12.5590 | 2000 | L |
| 10. | Jose Fernandez (23) | 12.4881 | 2016 | R |
| 11. | Gerrit Cole (27) | 12.3993 | 2018 | R |
| 12. | Randy Johnson+ (31) | 12.3453 | 1995 | L |
| 13. | Trevor Bauer (29) | 12.3288 | 2020 | R |
| 14. | Max Scherzer (35) | 12.2970 | 2020 | R |
| 15. | Randy Johnson+ (33) | 12.2958 | 1997 | L |
| 16. | Max Scherzer (33) | 12.2356 | 2018 | R |
| 17. | Justin Verlander (35) | 12.1963 | 2018 | R |
| 18. | Robbie Ray (27) | 12.1319 | 2019 | L |
| 19. | Dinelson Lamet (27) | 12.1304 | 2020 | R |
| 20. | Randy Johnson+ (34) | 12.1187 | 1998 | L |
| 21. | Aaron Nola (27) | 12.1121 | 2020 | R |
| 22. | Robbie Ray (25) | 12.1111 | 2017 | L |
| 23. | Justin Verlander (36) | 12.1076 | 2019 | R |
| 24. | Lucas Giolito (25) | 12.0691 | 2020 | R |
| 25. | Randy Johnson+ (35) | 12.0589 | 1999 | L |
| 26. | Max Scherzer (32) | 12.0199 | 2017 | R |
| 27. | Yu Darvish (26) | 11.8903 | 2013 | R |
| 28. | Chris Sale (26) | 11.8179 | 2015 | L |
| 29. | Pedro Martinez+ (28) | 11.7788 | 2000 | R |
| 30. | Corey Kluber (31) | 11.7103 | 2017 | R |
| 31. | Clayton Kershaw (27) | 11.6433 | 2015 | L |
| 32. | Lucas Giolito (24) | 11.6151 | 2019 | R |
| 33. | Gerrit Cole (29) | 11.5890 | 2020 | R |
| 34. | Randy Johnson+ (38) | 11.5615 | 2002 | L |
| 35. | Matthew Boyd (28) | 11.5576 | 2019 | L |
| 36. | Yu Darvish (32) | 11.5354 | 2019 | R |
| 37. | Nolan Ryan+ (40) | 11.4803 | 1987 | R |
| 38. | Luis Castillo (27) | 11.4429 | 2020 | R |
| 39. | Dwight Gooden (19) | 11.3945 | 1984 | R |
| 40. | Pedro Martinez+ (25) | 11.3743 | 1997 | R |
| 41. | Kerry Wood (26) | 11.3460 | 2003 | R |
| 42. | Trevor Bauer (27) | 11.3441 | 2018 | R |
| 43. | Nolan Ryan+ (42) | 11.3189 | 1989 | R |
| 44. | Curt Schilling (30) | 11.2883 | 1997 | R |
| 45. | Robbie Ray (24) | 11.2543 | 2016 | L |
| 46. | Jacob deGrom (31) | 11.2500 | 2019 | R |
| 47. | Kerry Wood (24) | 11.2027 | 2001 | R |
| 48. | Max Scherzer (31) | 11.1942 | 2016 | R |
| 49. | Jacob deGrom (30) | 11.1567 | 2018 | R |
| 50. | Chris Archer (28) | 11.1493 | 2017 | R |
| Rank | Player (age that year) | Strikeouts per 9 IP | Year | Throws |
| 51. | Brandon Woodruff (27) | 11.1176 | 2020 | R |
| 52. | Hideo Nomo (26) | 11.1010 | 1995 | R |
| 53. | Charlie Morton (35) | 11.0959 | 2019 | R |
| 54. | Max Scherzer (27) | 11.0782 | 2012 | R |
| 55. | Patrick Corbin (28) | 11.0700 | 2018 | L |
| 56. | Yu Darvish (33) | 11.0132 | 2020 | R |
| 57. | Blake Snell (25) | 11.0092 | 2018 | L |
| 58. | Oliver Perez (22) | 10.9745 | 2004 | L |
| 59. | Curt Schilling (35) | 10.9666 | 2002 | R |
| 60. | Erik Bedard (28) | 10.9286 | 2007 | L |
| 61. | Shane Bieber (24) | 10.8756 | 2019 | R |
| 62. | Max Scherzer (30) | 10.8630 | 2015 | R |
| 63. | Randy Johnson+ (29) | 10.8564 | 1993 | L |
| 64. | Carlos Carrasco (33) | 10.8529 | 2020 | R |
| 65. | Clayton Kershaw (26) | 10.8454 | 2014 | L |
| 66. | Charlie Morton (34) | 10.8323 | 2018 | R |
| 67. | Carlos Carrasco (31) | 10.8281 | 2018 | R |
| 68. | Stephen Strasburg (30) | 10.8086 | 2019 | R |
| 69. | Kenta Maeda (32) | 10.8000 | 2020 | R |
| 70. | Pedro Martinez+ (30) | 10.7910 | 2002 | R |
| 71. | Chris Sale (25) | 10.7586 | 2014 | L |
| 72. | Sam McDowell (22) | 10.7143 | 1965 | L |
| 73. | Luis Severino (23) | 10.7069 | 2017 | R |
| 74. | Chris Archer (26) | 10.6981 | 2015 | R |
| 75. | Trevor Bauer (28) | 10.6901 | 2019 | R |
| 76. | Jacob deGrom (29) | 10.6838 | 2017 | R |
| 77. | Noah Syndergaard (23) | 10.6824 | 2016 | R |
| 78. | Randy Johnson+ (30) | 10.6744 | 1994 | L |
| 79. | Luis Castillo (26) | 10.6678 | 2019 | R |
| 80. | Lance Lynn (32) | 10.6272 | 2019 | R |
| 81. | Randy Johnson+ (40) | 10.6242 | 2004 | L |
| 82. | Walker Buehler (24) | 10.6124 | 2019 | R |
| 83. | Michael Pineda (27) | 10.6053 | 2016 | R |
| 84. | Patrick Corbin (29) | 10.6040 | 2019 | L |
| 85. | Jack Flaherty (23) | 10.5891 | 2019 | R |
| 86. | Carlos Carrasco (28) | 10.5844 | 2015 | R |
| 87. | Nolan Ryan+ (26) | 10.5736 | 1973 | R |
| 88. | German Marquez (23) | 10.5612 | 2018 | R |
| 89. | Nolan Ryan+ (44) | 10.5607 | 1991 | R |
| 90. | Sandy Koufax+ (26) | 10.5461 | 1962 | L |
| 91. | Zack Greinke (27) | 10.5379 | 2011 | R |
| 92. | Sonny Gray (29) | 10.5228 | 2019 | R |
| 93. | Tim Lincecum (24) | 10.5066 | 2008 | R |
| 94. | Stephen Strasburg (28) | 10.4715 | 2017 | R |
| 95. | Johan Santana (25) | 10.4605 | 2004 | L |
| 96. | Mark Prior (22) | 10.4338 | 2003 | R |
| 97. | Nolan Ryan+ (25) | 10.4261 | 1972 | R |
| 98. | Tim Lincecum (25) | 10.4246 | 2009 | R |
| 99. | Sam McDowell (23) | 10.4202 | 1966 | L |
| 100. | Chris Archer (27) | 10.4156 | 2016 | R |
| Rank | Player (age that year) | Strikeouts per 9 IP | Year | Throws |
| 101. | Scott Kazmir (23) | 10.4081 | 2007 | L |
| 102. | Yu Darvish (25) | 10.3955 | 2012 | R |
| 103. | Roger Clemens (35) | 10.3935 | 1998 | R |
| 104. | Curt Schilling (36) | 10.3929 | 2003 | R |
| 105. | Clayton Kershaw (29) | 10.3886 | 2017 | L |
| 106. | Nolan Ryan+ (29) | 10.3505 | 1976 | R |
| 107. | Luis Severino (24) | 10.3484 | 2018 | R |
| 108. | Nick Pivetta (25) | 10.3171 | 2018 | R |
| 109. | Randy Johnson+ (28) | 10.3122 | 1992 | L |
| 110. | Max Scherzer (29) | 10.2935 | 2014 | R |
| 111. | Curt Schilling (34) | 10.2740 | 2001 | R |
| 112. | Corey Kluber (28) | 10.2730 | 2014 | R |
| 113. | Nolan Ryan+ (30) | 10.2642 | 1977 | R |
| 114. | Zac Gallen (24) | 10.2500 | 2020 | R |
| 115. | David Cone (34) | 10.2462 | 1997 | R |
| 116. | Sandy Koufax+ (29) | 10.2423 | 1965 | L |
| 117. | Nolan Ryan+ (43) | 10.2353 | 1990 | R |
| 118. | Jimmy Nelson (28) | 10.2148 | 2017 | R |
| 119. | Randy Johnson+ (27) | 10.1921 | 1991 | L |
| 120. | Brandon Morrow (26) | 10.1877 | 2011 | R |
| 121. | Aaron Nola (26) | 10.1862 | 2019 | R |
| 122. | Carlos Carrasco (30) | 10.1700 | 2017 | R |
| 123. | Mark Prior (24) | 10.1520 | 2005 | R |
| 124. | Bartolo Colon (27) | 10.1489 | 2000 | R |
| 125. | Sandy Koufax+ (24) | 10.1314 | 1960 | L |
| 126. | Stephen Strasburg (25) | 10.1302 | 2014 | R |
| 127. | Hideo Nomo (28) | 10.1141 | 1997 | R |
| 128. | Justin Verlander (26) | 10.0875 | 2009 | R |
| 129. | Max Scherzer (28) | 10.0778 | 2013 | R |
| 130. | Yu Darvish (30) | 10.0768 | 2017 | R |
| 131. | Curt Schilling (31) | 10.0496 | 1998 | R |
| 132. | Justin Verlander (33) | 10.0410 | 2016 | R |
| 133. | Jason Schmidt (31) | 10.0400 | 2004 | R |
| 134. | Ben Sheets (25) | 10.0253 | 2004 | R |
| 135. | Trevor Bauer (26) | 10.0038 | 2017 | R |
| 136. | Mike Scott (31) | 10.0024 | 1986 | R |
| 137. | Hideo Nomo (32) | 10.0000 | 2001 | R |
| 138. | Anibal Sanchez (29) | 9.9890 | 2013 | R |
| 139. | Rick Ankiel (20) | 9.9771 | 2000 | L |
| 140. | Nolan Ryan+ (31) | 9.9716 | 1978 | R |
| 141. | Madison Bumgarner (26) | 9.9662 | 2016 | L |
| 142. | Jon Lester (25) | 9.9590 | 2009 | L |
| 143. | Roger Clemens (34) | 9.9545 | 1997 | R |
| 144. | Mike Foltynewicz (26) | 9.9344 | 2018 | R |
| 145. | Corey Kluber (29) | 9.9324 | 2015 | R |
| 146. | Pedro Martinez+ (31) | 9.9321 | 2003 | R |
| 147. | Nolan Ryan+ (27) | 9.9289 | 1974 | R |
| 148. | Roger Clemens (25) | 9.9205 | 1988 | R |
| 149. | Jon Gray (24) | 9.9107 | 2016 | R |
| 150. | David Cone (27) | 9.9071 | 1990 | R |
| Rank | Player (age that year) | Strikeouts per 9 IP | Year | Throws |
| 151. | J.R. Richard (28) | 9.9044 | 1978 | R |
| 152. | Yovani Gallardo (23) | 9.8887 | 2009 | R |
| 153. | Francisco Liriano (31) | 9.8839 | 2015 | L |
| 154. | Jose Quintana (28) | 9.8746 | 2017 | L |
| 155. | Andy Benes (26) | 9.8704 | 1994 | R |
| 156. | Dylan Bundy (27) | 9.8680 | 2020 | R |
| 157. | Aaron Nola (24) | 9.8571 | 2017 | R |
| 158. | A.J. Burnett (36) | 9.8482 | 2013 | R |
| 159. | David Price (28) | 9.8215 | 2014 | L |
| 160. | Nolan Ryan+ (39) | 9.8090 | 1986 | R |
| 161. | Drew Pomeranz (27) | 9.8086 | 2016 | L |
| 162. | John Smoltz+ (29) | 9.7924 | 1996 | R |
| 163. | Tim Lincecum (26) | 9.7912 | 2010 | R |
| 164. | Masahiro Tanaka (28) | 9.7907 | 2017 | R |
| 165. | J.A. Happ (35) | 9.7767 | 2018 | L |
| 166. | Javier Vazquez (32) | 9.7660 | 2009 | R |
| 167. | Jonathan Sanchez (26) | 9.7531 | 2009 | L |
| 168. | Jose Fernandez (20) | 9.7471 | 2013 | R |
| 169. | Clayton Kershaw (21) | 9.7368 | 2009 | L |
| 170. | Jon Lester (26) | 9.7356 | 2010 | L |
| 171. | Tyson Ross (28) | 9.7347 | 2015 | R |
| 172. | Yovani Gallardo (24) | 9.7297 | 2010 | R |
| 173. | Jose Berrios (26) | 9.7143 | 2020 | R |
| 174. | Francisco Liriano (30) | 9.7023 | 2014 | L |
| 175. | Herb Score (22) | 9.6994 | 1955 | L |
| 176. | Framber Valdez (26) | 9.6792 | 2020 | L |
| 177. | Jake Peavy (26) | 9.6716 | 2007 | R |
| Hyun Jin Ryu (33) | 9.6716 | 2020 | L | |
| 179. | Pedro Martinez+ (26) | 9.6676 | 1998 | R |
| 180. | Jacob deGrom (27) | 9.6597 | 2015 | R |
| 181. | Johan Santana (28) | 9.6575 | 2007 | L |
| 182. | Nolan Ryan+ (37) | 9.6534 | 1984 | R |
| 183. | Dylan Bundy (25) | 9.6466 | 2018 | R |
| 184. | Madison Bumgarner (25) | 9.6458 | 2015 | L |
| 185. | Matt Harvey (24) | 9.6393 | 2013 | R |
| 186. | J.R. Richard (29) | 9.6363 | 1979 | R |
| 187. | James Shields (33) | 9.6079 | 2015 | R |
| 188. | Roger Clemens (39) | 9.6000 | 2002 | R |
| 189. | Jake Peavy (24) | 9.5764 | 2005 | R |
| 190. | Mario Soto (25) | 9.5705 | 1982 | R |
| 191. | Justin Verlander (34) | 9.5680 | 2017 | R |
| 192. | Clayton Kershaw (23) | 9.5657 | 2011 | L |
| 193. | Zack Greinke (33) | 9.5634 | 2017 | R |
| Jake Peavy (25) | 9.5634 | 2006 | R | |
| 195. | A.J. Burnett (30) | 9.5614 | 2007 | R |
| 196. | Ubaldo Jimenez (29) | 9.5584 | 2013 | R |
| 197. | Tom Griffin (21) | 9.5575 | 1969 | R |
| 198. | Jon Gray (26) | 9.5571 | 2018 | R |
| 199. | Jonathan Sanchez (27) | 9.5431 | 2010 | L |
| 200. | Clayton Kershaw (31) | 9.5383 | 2019 | L |
| Rank | Player (age that year) | Strikeouts per 9 IP | Year | Throws |
| 201. | Lance Lynn (33) | 9.5357 | 2020 | R |
| 202. | Roger Clemens (33) | 9.5316 | 1996 | R |
| 203. | Jim Maloney (23) | 9.5273 | 1963 | R |
| 204. | Carlos Martinez (25) | 9.5268 | 2017 | R |
| 205. | Jason Schmidt (29) | 9.5180 | 2002 | R |
| 206. | Felix Hernandez (27) | 9.5139 | 2013 | R |
| 207. | Sid Fernandez (22) | 9.5108 | 1985 | L |
| 208. | Corey Kluber (30) | 9.5023 | 2016 | R |
| 209. | Zack Greinke (25) | 9.4971 | 2009 | R |
| 210. | Aaron Nola (25) | 9.4945 | 2018 | R |
| 211. | Herb Score (23) | 9.4933 | 1956 | L |
| 212. | Chris Sale (24) | 9.4899 | 2013 | L |
| 213. | Ricky Nolasco (26) | 9.4865 | 2009 | R |
| Danny Salazar (25) | 9.4865 | 2015 | R | |
| 215. | Sandy Koufax+ (25) | 9.4694 | 1961 | L |
| 216. | Sam McDowell (25) | 9.4684 | 1968 | L |
| 217. | Edinson Volquez (24) | 9.4592 | 2008 | R |
| 218. | Felix Hernandez (28) | 9.4576 | 2014 | R |
| 219. | Jose Berrios (24) | 9.4523 | 2018 | R |
| 220. | Andrew Heaney (29) | 9.4500 | 2020 | L |
| 221. | Matt Clement (29) | 9.4475 | 2004 | R |
| 222. | Matt Clement (27) | 9.4390 | 2002 | R |
| 223. | Francisco Liriano (26) | 9.4383 | 2010 | L |
| 224. | Johan Santana (27) | 9.4365 | 2006 | L |
| 225. | Eduardo Rodriguez (26) | 9.4279 | 2019 | L |
| 226. | Danny Duffy (27) | 9.4174 | 2016 | L |
| 227. | Pedro Martinez+ (32) | 9.4147 | 2004 | R |
| 228. | David Cone (29) | 9.4085 | 1992 | R |
| 229. | Frank Tanana (21) | 9.4080 | 1975 | L |
| 230. | Javier Vazquez (26) | 9.4032 | 2003 | R |
| 231. | Don Wilson (24) | 9.4000 | 1969 | R |
| 232. | Max Fried (25) | 9.3984 | 2019 | L |
| 233. | Stephen Strasburg (24) | 9.3934 | 2013 | R |
| 234. | A.J. Burnett (31) | 9.3931 | 2008 | R |
| 235. | Jorge De La Rosa (28) | 9.3892 | 2009 | L |
| 236. | Jake Peavy (23) | 9.3607 | 2004 | R |
| 237. | Jered Weaver (27) | 9.3477 | 2010 | R |
| 238. | Gio Gonzalez (26) | 9.3462 | 2012 | L |
| 239. | Bob Veale (29) | 9.3383 | 1965 | L |
| 240. | Clayton Kershaw (22) | 9.3377 | 2010 | L |
| 241. | Zack Godley (28) | 9.3364 | 2018 | R |
| 242. | Nolan Ryan+ (41) | 9.3273 | 1988 | R |
| 243. | David Cone (28) | 9.3223 | 1991 | R |
| 244. | Jake Odorizzi (24) | 9.3214 | 2014 | R |
| 245. | Mike Clevinger (27) | 9.3150 | 2018 | R |
| 246. | Ian Kennedy (30) | 9.3030 | 2015 | R |
| 247. | Corey Kluber (32) | 9.2930 | 2018 | R |
| 248. | John Smoltz+ (31) | 9.2863 | 1998 | R |
| 249. | Francisco Liriano (32) | 9.2761 | 2016 | L |
| 250. | Jake Arrieta (29) | 9.2751 | 2015 | R |
| Rank | Player (age that year) | Strikeouts per 9 IP | Year | Throws |
| 251. | Jeff Samardzija (27) | 9.2748 | 2012 | R |
| 252. | Ian Kennedy (29) | 9.2687 | 2014 | R |
| 253. | Anibal Sanchez (27) | 9.2598 | 2011 | R |
| 254. | Chris Sale (27) | 9.2515 | 2016 | L |
| 255. | Johan Santana (26) | 9.2460 | 2005 | L |
| 256. | Luis Tiant (26) | 9.2246 | 1967 | R |
| 257. | Hideo Nomo (27) | 9.2234 | 1996 | R |
| 258. | Pedro Martinez+ (24) | 9.2215 | 1996 | R |
| 259. | Brandon Duckworth (26) | 9.2209 | 2002 | R |
| 260. | Carlos Martinez (23) | 9.2171 | 2015 | R |
| 261. | Mark Langston (25) | 9.2131 | 1986 | L |
| 262. | Mat Latos (22) | 9.2112 | 2010 | R |
| 263. | Zack Greinke (30) | 9.2076 | 2014 | R |
| 264. | Cliff Lee (32) | 9.2063 | 2011 | L |
| 265. | Lance Lynn (25) | 9.2045 | 2012 | R |
| 266. | Luis Tiant (27) | 9.1974 | 1968 | R |
| 267. | Noah Syndergaard (26) | 9.1973 | 2019 | R |
| 268. | Dave Boswell (21) | 9.1949 | 1966 | R |
| 269. | Max Scherzer (24) | 9.1937 | 2009 | R |
| 270. | Tim Lincecum (28) | 9.1935 | 2012 | R |
| 271. | David Price (29) | 9.1906 | 2015 | L |
| 272. | Sam McDowell (21) | 9.1904 | 1964 | L |
| 273. | Kenta Maeda (28) | 9.1708 | 2016 | R |
| 274. | Carlos Rodon (23) | 9.1636 | 2016 | L |
| 275. | Roger Clemens (41) | 9.1540 | 2004 | R |
| 276. | Kerry Wood (25) | 9.1404 | 2002 | R |
| 277. | Tim Lincecum (27) | 9.1244 | 2011 | R |
| 278. | Josh Johnson (26) | 9.1143 | 2010 | R |
| 279. | Cole Hamels (31) | 9.1130 | 2015 | L |
| 280. | Sonny Siebert (28) | 9.1113 | 1965 | R |
| 281. | Michael Pineda (22) | 9.1053 | 2011 | R |
| 282. | Cole Hamels (26) | 9.1006 | 2010 | L |
| 283. | Sid Fernandez (25) | 9.0963 | 1988 | L |
| 284. | Justin Masterson (28) | 9.0933 | 2013 | R |
| 285. | Orlando Hernandez (40) | 9.0924 | 2006 | R |
| 286. | Jon Lester (31) | 9.0878 | 2015 | L |
| 287. | Tom Seaver+ (26) | 9.0838 | 1971 | R |
| 288. | Sid Fernandez (27) | 9.0836 | 1990 | L |
| 289. | Zack Wheeler (24) | 9.0809 | 2014 | R |
| 290. | Jason Hammel (32) | 9.0703 | 2015 | R |
| 291. | Madison Bumgarner (24) | 9.0690 | 2014 | L |
| 292. | David Cone (35) | 9.0578 | 1998 | R |
| 293. | Clayton Kershaw (24) | 9.0527 | 2012 | L |
| 294. | German Marquez (24) | 9.0517 | 2019 | R |
| 295. | David Price (32) | 9.0511 | 2018 | L |
| 296. | Dennis Eckersley+ (21) | 9.0301 | 1976 | R |
| 297. | Cole Hamels (28) | 9.0279 | 2012 | L |
| 298. | Justin Verlander (29) | 9.0252 | 2012 | R |
| 299. | Anthony DeSclafani (29) | 9.0180 | 2019 | R |
| 300. | Drew Pomeranz (28) | 9.0173 | 2017 | L |
| Rank | Player (age that year) | Strikeouts per 9 IP | Year | Throws |
| 301. | John Smoltz+ (28) | 9.0156 | 1995 | R |
| 302. | Chad Billingsley (23) | 9.0150 | 2008 | R |
| 303. | Jason Schmidt (30) | 9.0144 | 2003 | R |
| 304. | Jeff Samardzija (28) | 9.0140 | 2013 | R |
| 305. | Jon Lester (30) | 9.0137 | 2014 | L |
| 306. | Nolan Ryan+ (32) | 9.0135 | 1979 | R |
| 307. | Kevin Brown (33) | 9.0000 | 1998 | R |
| Yovani Gallardo (26) | 9.0000 | 2012 | R | |
| Zack Greinke (36) | 9.0000 | 2020 | R | |
| Andrew Heaney (27) | 9.0000 | 2018 | L | |
| Darryl Kile (27) | 9.0000 | 1996 | R | |
| Sandy Koufax+ (28) | 9.0000 | 1964 | L | |
| Chris Sale (23) | 9.0000 | 2012 | L | |
| 314. | Sam McDowell (24) | 8.9873 | 1967 | L |
| 315. | Yovani Gallardo (25) | 8.9855 | 2011 | R |
| 316. | Zack Wheeler (29) | 8.9846 | 2019 | R |
| 317. | Mike Fiers (30) | 8.9834 | 2015 | R |
| 318. | Cliff Lee (34) | 8.9731 | 2013 | L |
| 319. | Sam McDowell (27) | 8.9705 | 1970 | L |
| 320. | Cole Hamels (32) | 8.9701 | 2016 | L |
| 321. | Tyson Ross (27) | 8.9693 | 2014 | R |
| 322. | Drew Hutchison (23) | 8.9675 | 2014 | R |
| 323. | Jon Lester (33) | 8.9668 | 2017 | L |
| 324. | Justin Verlander (28) | 8.9641 | 2011 | R |
| 325. | Bobby Witt (26) | 8.9595 | 1990 | R |
| 326. | Matt Garza (27) | 8.9545 | 2011 | R |
| 327. | Matthew Boyd (29) | 8.9503 | 2020 | L |
| 328. | Justin Verlander (30) | 8.9450 | 2013 | R |
| 329. | A.J. Burnett (25) | 8.9413 | 2002 | R |
| 330. | Johnny Cueto (28) | 8.9384 | 2014 | R |
| 331. | Rick Porcello (29) | 8.9373 | 2018 | R |
| 332. | Matt Harvey (26) | 8.9366 | 2015 | R |
| 333. | Curt Schilling (29) | 8.9345 | 1996 | R |
| 334. | Jose Rijo (29) | 8.9304 | 1994 | R |
| 335. | CC Sabathia (27) | 8.9289 | 2008 | L |
| 336. | David Price (30) | 8.9217 | 2016 | L |
| 337. | Jim Maloney (24) | 8.9167 | 1964 | R |
| 338. | Alex Wood (23) | 8.9126 | 2014 | L |
| 339. | Andy Benes (29) | 8.8983 | 1997 | R |
| 340. | Madison Bumgarner (23) | 8.8957 | 2013 | L |
| 341. | Kent Mercker (26) | 8.8932 | 1994 | L |
| 342. | Jose Rijo (23) | 8.8889 | 1988 | R |
| 343. | Jeff Samardzija (32) | 8.8844 | 2017 | R |
| 344. | Matt Moore (23) | 8.8816 | 2012 | L |
| 345. | Josh Beckett (28) | 8.8795 | 2008 | R |
| 346. | Derek Holland (31) | 8.8774 | 2018 | L |
| 347. | Cole Hamels (34) | 8.8741 | 2018 | L |
| 348. | Jake Odorizzi (28) | 8.8722 | 2018 | R |
| 349. | CC Sabathia (31) | 8.8650 | 2012 | L |
| 350. | Roger Clemens (31) | 8.8594 | 1994 | R |
| Rank | Player (age that year) | Strikeouts per 9 IP | Year | Throws |
| 351. | R.A. Dickey (37) | 8.8588 | 2012 | R |
| 352. | Sandy Koufax+ (27) | 8.8553 | 1963 | L |
| 353. | Javier Vazquez (30) | 8.8477 | 2007 | R |
| 354. | Clayton Kershaw (25) | 8.8475 | 2013 | L |
| Oliver Perez (25) | 8.8475 | 2007 | L | |
| 356. | Pedro Astacio (31) | 8.8472 | 2000 | R |
| 357. | Daisuke Matsuzaka (26) | 8.8388 | 2007 | R |
| 358. | Lance Lynn (26) | 8.8364 | 2013 | R |
| 359. | Zack Wheeler (28) | 8.8355 | 2018 | R |
| 360. | Pedro Martinez+ (22) | 8.8341 | 1994 | R |
| 361. | Sandy Koufax+ (30) | 8.8328 | 1966 | L |
| 362. | Carlos Zambrano (25) | 8.8318 | 2006 | R |
| 363. | Gio Gonzalez (27) | 8.8313 | 2013 | L |
| 364. | Cliff Lee (33) | 8.8294 | 2012 | L |
| 365. | Bud Norris (27) | 8.8218 | 2012 | R |
| 366. | Kevin Appier (28) | 8.8155 | 1996 | R |
| James Shields (30) | 8.8155 | 2012 | R | |
| 368. | Sam McDowell (26) | 8.8105 | 1969 | L |
| 369. | Sid Fernandez (23) | 8.8091 | 1986 | L |
| 370. | Nolan Ryan+ (35) | 8.8083 | 1982 | R |
| 371. | Todd Stottlemyre (30) | 8.7997 | 1995 | R |
| 372. | Madison Bumgarner (29) | 8.7978 | 2019 | L |
| 373. | Ervin Santana (25) | 8.7945 | 2008 | R |
| 374. | Tim Lincecum (29) | 8.7875 | 2013 | R |
| 375. | Justin Verlander (27) | 8.7860 | 2010 | R |
| 376. | Sean Newcomb (25) | 8.7805 | 2018 | L |
| 377. | Gio Gonzalez (25) | 8.7772 | 2011 | L |
| 378. | Colby Lewis (30) | 8.7761 | 2010 | R |
| 379. | Shelby Miller (22) | 8.7750 | 2013 | R |
| 380. | Tom Seaver+ (25) | 8.7626 | 1970 | R |
| 381. | Al Downing (22) | 8.7609 | 1963 | L |
| 382. | Jose Berrios (25) | 8.7604 | 2019 | R |
| 383. | Luis Castillo (25) | 8.7525 | 2018 | R |
| 384. | Dan Haren (28) | 8.7515 | 2009 | R |
| 385. | Garrett Richards (26) | 8.7510 | 2014 | R |
| 386. | Jon Lester (32) | 8.7484 | 2016 | L |
| 387. | David Price (25) | 8.7459 | 2011 | L |
| 388. | David Price (26) | 8.7441 | 2012 | L |
| 389. | Gerrit Cole (24) | 8.7404 | 2015 | R |
| 390. | Bob Moose (21) | 8.7353 | 1969 | R |
| 391. | Mike Mussina+ (28) | 8.7329 | 1997 | R |
| 392. | Steve Carlton+ (38) | 8.7250 | 1983 | L |
| 393. | CC Sabathia (30) | 8.7219 | 2011 | L |
| 394. | Dwight Gooden (20) | 8.7181 | 1985 | R |
| 395. | Kevin Gausman (25) | 8.7161 | 2016 | R |
| 396. | Jake Arrieta (31) | 8.7149 | 2017 | R |
| 397. | Cole Hamels (30) | 8.7068 | 2014 | L |
| 398. | Steve Carlton+ (37) | 8.7057 | 1982 | L |
| 399. | Josh Beckett (27) | 8.7010 | 2007 | R |
| 400. | Roger Clemens (38) | 8.7005 | 2001 | R |
| Rank | Player (age that year) | Strikeouts per 9 IP | Year | Throws |
| 401. | Ryan Dempster (33) | 8.6935 | 2010 | R |
| Brett Myers (24) | 8.6935 | 2005 | R | |
| 403. | Trevor Bauer (24) | 8.6932 | 2015 | R |
| 404. | Juan Pizarro (24) | 8.6918 | 1961 | L |
| 405. | Mickey Lolich (28) | 8.6900 | 1969 | L |
| 406. | Gerrit Cole (26) | 8.6897 | 2017 | R |
| 407. | Cole Hamels (23) | 8.6891 | 2007 | L |
| 408. | Ubaldo Jimenez (26) | 8.6887 | 2010 | R |
| 409. | Joey Lucchesi (26) | 8.6884 | 2019 | L |
| 410. | Chris Young (28) | 8.6879 | 2007 | R |
| 411. | Vida Blue (21) | 8.6827 | 1971 | L |
| 412. | Hugh Daily (36) | 8.6824 | 1884 | R |
| 413. | Gio Gonzalez (30) | 8.6786 | 2016 | L |
| 414. | Mark Langston (26) | 8.6691 | 1987 | L |
| 415. | Jake Arrieta (30) | 8.6655 | 2016 | R |
| 416. | Bob Johnson (27) | 8.6636 | 1970 | R |
| 417. | Gio Gonzalez (29) | 8.6584 | 2015 | L |
| 418. | Al Leiter (34) | 8.6538 | 2000 | L |
| 419. | Jim Maloney (26) | 8.6528 | 1966 | R |
| 420. | Felix Hernandez (26) | 8.6509 | 2012 | R |
| 421. | Jon Lester (35) | 8.6505 | 2019 | L |
| 422. | Chuck Finley (32) | 8.6453 | 1995 | L |
| 423. | Chan Ho Park (27) | 8.6416 | 2000 | R |
| 424. | Mike Minor (31) | 8.6400 | 2019 | L |
| Javier Vazquez (31) | 8.6400 | 2008 | R | |
| 426. | Jason Schmidt (32) | 8.6337 | 2005 | R |
| 427. | Kevin Gausman (26) | 8.6304 | 2017 | R |
| 428. | Pedro Martinez+ (33) | 8.6267 | 2005 | R |
| 429. | Collin McHugh (29) | 8.6264 | 2016 | R |
| 430. | Dwight Gooden (25) | 8.6261 | 1990 | R |
| 431. | Jeff Fassero (33) | 8.6245 | 1996 | L |
| 432. | Zack Greinke (34) | 8.6244 | 2018 | R |
| 433. | Bruce Hurst (28) | 8.6214 | 1986 | L |
| 434. | John Smoltz+ (40) | 8.6207 | 2007 | R |
| 435. | Barry Zito (23) | 8.6081 | 2001 | L |
| 436. | Mario Soto (23) | 8.6060 | 1980 | R |
| 437. | Jake Peavy (27) | 8.6027 | 2008 | R |
| 438. | Ubaldo Jimenez (27) | 8.6018 | 2011 | R |
| John Lackey (37) | 8.6018 | 2016 | R | |
| 440. | Tanner Roark (32) | 8.6008 | 2019 | R |
| 441. | Jim Maloney (25) | 8.6005 | 1965 | R |
| 442. | Yordano Ventura (24) | 8.5959 | 2015 | R |
| 443. | Brett Myers (25) | 8.5909 | 2006 | R |
| 444. | Michael Wacha (25) | 8.5835 | 2017 | R |
| 445. | Dan Haren (27) | 8.5833 | 2008 | R |
| 446. | Hideo Nomo (31) | 8.5737 | 2000 | R |
| 447. | Edinson Volquez (28) | 8.5730 | 2012 | R |
| 448. | Lance Lynn (28) | 8.5722 | 2015 | R |
| Drew Smyly (27) | 8.5722 | 2016 | L | |
| 450. | Homer Bailey (27) | 8.5694 | 2013 | R |
| Rank | Player (age that year) | Strikeouts per 9 IP | Year | Throws |
| John Lackey (26) | 8.5694 | 2005 | R | |
| 452. | Brandon Webb (24) | 8.5683 | 2003 | R |
| 453. | Mat Latos (23) | 8.5678 | 2011 | R |
| 454. | Ramon Martinez (22) | 8.5647 | 1990 | R |
| 455. | Tom Seaver+ (27) | 8.5534 | 1972 | R |
| 456. | Felix Hernandez (25) | 8.5506 | 2011 | R |
| 457. | Jon Lester (27) | 8.5461 | 2011 | L |
| 458. | Dick Selma (25) | 8.5437 | 1969 | R |
| 459. | Chuck Finley (35) | 8.5433 | 1998 | L |
| 460. | CC Sabathia (20) | 8.5342 | 2001 | L |
| 461. | Brady Singer (23) | 8.5337 | 2020 | R |
| 462. | A.J. Burnett (28) | 8.5263 | 2005 | R |
| 463. | Felix Hernandez (29) | 8.5240 | 2015 | R |
| 464. | Marco Estrada (33) | 8.5161 | 2017 | R |
| Bud Norris (26) | 8.5161 | 2011 | R | |
| 466. | Robert Person (30) | 8.5154 | 2000 | R |
| 467. | Chuck Finley (34) | 8.5061 | 1997 | L |
| 468. | Ryan Dempster (34) | 8.4959 | 2011 | R |
| 469. | Jeremy Bonderman (23) | 8.4953 | 2006 | R |
| 470. | Bob Veale (33) | 8.4948 | 1969 | L |
| 471. | Sterling Hitchcock (28) | 8.4895 | 1999 | L |
| 472. | Sonny Gray (27) | 8.4825 | 2017 | R |
| 473. | John Maine (26) | 8.4817 | 2007 | R |
| 474. | Steve Carlton+ (36) | 8.4789 | 1981 | L |
| 475. | A.J. Burnett (32) | 8.4783 | 2009 | R |
| 476. | Zack Greinke (28) | 8.4772 | 2012 | R |
| 477. | Roy Halladay+ (34) | 8.4736 | 2011 | R |
| 478. | John Smoltz+ (30) | 8.4727 | 1997 | R |
| 479. | Andy Benes (27) | 8.4716 | 1995 | R |
| 480. | Aaron Harang (29) | 8.4691 | 2007 | R |
| 481. | Steve Carlton+ (35) | 8.4671 | 1980 | L |
| 482. | Mike Scott (32) | 8.4670 | 1987 | R |
| 483. | Dave Burba (33) | 8.4669 | 2000 | R |
| 484. | Ian Kennedy (31) | 8.4634 | 2016 | R |
| Max Scherzer (25) | 8.4634 | 2010 | R | |
| 486. | Randy Johnson+ (44) | 8.4620 | 2008 | L |
| 487. | Mark Langston (28) | 8.4600 | 1989 | L |
| 488. | Floyd Bannister (30) | 8.4589 | 1985 | L |
| 489. | Hal Newhouser+ (25) | 8.4567 | 1946 | L |
| 490. | Nolan Ryan+ (34) | 8.4564 | 1981 | R |
| 491. | Nolan Ryan+ (28) | 8.4545 | 1975 | R |
| 492. | Kevin Brown (35) | 8.4522 | 2000 | R |
| 493. | Matt Cain (21) | 8.4493 | 2006 | R |
| 494. | Tom Gordon (21) | 8.4479 | 1989 | R |
| 495. | Patrick Corbin (27) | 8.4464 | 2017 | L |
| 496. | Rich Hill (27) | 8.4462 | 2007 | L |
| 497. | Wandy Rodriguez (30) | 8.4457 | 2009 | L |
| 498. | Marco Estrada (32) | 8.4375 | 2016 | R |
| Chuck Finley (36) | 8.4375 | 1999 | L | |
| 500. | Josh Beckett (29) | 8.4349 | 2009 | R |
