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Transactions listed are from November 1 of previous year to April 1 of the following year.
December 31, 1920
Traded Braggo Roth to the New York Yankees. Received Duffy Lewis and George Mogridge.
May 31, 1921 (Standings)
Traded Frank Ellerbe to the St. Louis Browns. Received Earl Smith.
June 29, 1921 (Standings)
Tony Brottem selected by the Pittsburgh Pirates off waivers.
August 3, 1921 (Standings)
Purchased George Foss from Tampa (Florida State).
Purchased Bobby LaMotte from Tampa (Florida State).
August 20, 1921 (Standings)
Selected Donie Bush off waivers from the Detroit Tigers.
September, 1921 (Standings)
Purchased Goose Goslin from Columbia (South Atlantic) for $7,000.
January 10, 1922
Traded Jose Acosta and Bing Miller to the Philadelphia Athletics. Received Joe Dugan.
Traded Joe Dugan and Frank O'Rourke to the Boston Red Sox. Received Roger Peckinpaugh.