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Lost World Series (4-2) to Chicago White Sox |

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The greatest single season team performance in baseball history!
Transactions listed are from November 1 of previous year to April 1 of the following year.
October 24, 1905
Traded Jake Weimer to the Cincinnati Reds. Received Jimmy Sebring and Harry Steinfeldt.
December 13, 1905
Traded Jack O'Neill and Big Jeff Pfeffer to the Boston Beaneaters. Received Pat Moran.
December 15, 1905
Traded Buttons Briggs, Doc Casey, Billy Maloney, Jack McCarthy and $2,000 to the Brooklyn Superbas. Received Jimmy Sheckard.
January 3, 1906
Sold Hans Lobert to the Cincinnati Reds. (Date given is approximate. Exact date is uncertain.)
March 9, 1906
Traded Charles Miller (minors) and Louis Schaub (minors) to Wheeling (Central). Received Bull Smith.
April 28, 1906 (Standings)
Traded Hub Knolls to the Brooklyn Superbas. Received Doc Gessler.
May 7, 1906 (Standings)
Selected Jack Harper off waivers from the Cincinnati Reds.
June 2, 1906 (Standings)
Traded Bob Wicker to the Cincinnati Reds. Received Orval Overall and $2,000.
July 1, 1906 (Standings)
Traded Fred Beebe, Pete Noonan and cash to the St. Louis Cardinals. Received Jack Taylor.
August, 1906 (Standings)
Purchased Kid Durbin from Joplin (Western Association).
September, 1906 (Standings)
Drafted Bill Sweeney from Portland (PCL) in the 1906 rule 5 draft. (Date given is approximate. Exact date is uncertain.)
September 1, 1906 (Standings)
Drafted Newt Randall from Denver (Western) in the 1906 rule 5 draft.
October, 1906 (Standings)
Traded a player to be named later, Jack Harper and cash to the Cincinnati Reds. Received a player to be named later. The Chicago Cubs sent Doc Gessler (January 16, 1907) to the Cincinnati Reds to complete the trade. The Cincinnati Reds sent Chick Fraser (January 16, 1907) to the Chicago Cubs to complete the trade.