Transactions listed are from November 1 of previous year to April 1 of the following year.
The Detroit Tigers traded Roy Crumpler, Sammy Hale, Jim Middleton, Joe Sargent, Suds Sutherland and $30,000 to Portland (PCL) for Syl Johnson and Herman Pillette.
The Chicago White Sox purchased Ferdie Schupp from the Brooklyn Robins.
The New York Giants traded George Burns, Mike Gonzalez and $150,000 to the Cincinnati Reds for Heinie Groh.
The New York Giants purchased Jimmy O'Connell from San Francisco (PCL) for $75,000.
The St. Louis Browns selected Chick Shorten off waivers from the Detroit Tigers.
Los Angeles (PCL) traded a player to be named later and Jigger Statz to the Chicago Cubs for a player to be named later. Los Angeles (PCL) sent Vic Aldridge (January, 1922) to the Chicago Cubs to complete the trade. The Chicago Cubs sent Elmer Ponder (January, 1922), John Sullivan (January, 1922), Babe Twombly (January, 1922), Tom Daly (February, 1922) and Charlie Deal (April, 1922) to Los Angeles (PCL) to complete the trade.
The New York Yankees traded Rip Collins, Roger Peckinpaugh, Bill Piercy and Jack Quinn to the Boston Red Sox for Joe Bush, Sam Jones and Everett Scott.
The Cleveland Indians traded George Burns, Joe Harris and Elmer Smith to the Boston Red Sox for Stuffy McInnis.
The Detroit Tigers selected George Cutshaw off waivers from the Pittsburgh Pirates.
Little Rock (Southern Association) traded an option on any player on team to the New York Giants for Joe Connolly.
Gabby Hartnett sent from Worcester (Eastern) to the Chicago Cubs in an unknown transaction.
The Philadelphia Phillies traded Snake Henry to New Orleans (Southern Association) for Roy Leslie.
Dave Keefe sent from the Philadelphia Athletics to the Cleveland Indians in an unknown transaction.
The Pittsburgh Pirates released Dave Robertson.
The Brooklyn Robins purchased Dazzy Vance from New Orleans (Southern Association).
Portland (PCL) purchased Frank Bruggy from the Philadelphia Phillies for $6,500.
The Washington Senators traded Jose Acosta and Bing Miller to the Philadelphia Athletics for Joe Dugan.
The Washington Senators traded Joe Dugan and Frank O'Rourke to the Boston Red Sox for Roger Peckinpaugh.
Louisville (American Association) purchased Lyman Lamb from the St. Louis Browns.
The Brooklyn Robins purchased Sam Crane from the Cincinnati Reds.
The Chicago White Sox purchased Jose Acosta from the Philadelphia Athletics.
The Philadelphia Athletics purchased Doc Johnston from the Cleveland Indians.
The Cincinnati Reds traded Larry Kopf and Rube Marquard to the Boston Braves for Jack Scott.
The Boston Red Sox selected Alex Ferguson off waivers from the New York Yankees.
The Brooklyn Robins purchased Possum Whitted from the Pittsburgh Pirates.
The Philadelphia Athletics selected Ralph Young off waivers from the Detroit Tigers.
The Boston Braves returned Jimmie Wilson to New Haven (Eastern) following previous purchase.
The New York Yankees purchased Whitey Witt from the Philadelphia Athletics.
The New York Giants signed Dave Robertson as a free agent.
The Chicago White Sox purchased Harry Courtney from the Washington Senators.
The Pittsburgh Pirates purchased Jack Hammond from the Cleveland Indians.
Portland (PCL) traded Frank Bruggy to the Philadelphia Athletics for Frank Brazill, Harvey Freeman and Ollie Fuhrman.
The Chicago White Sox traded players to be named later, Doug McWeeny and $100,000 to San Francisco (PCL) for players to be named later and Willie Kamm. The Chicago White Sox sent Shovel Hodge (September 7, 1922) and Eddie Mulligan (October 24, 1922) to San Francisco (PCL) to complete the trade.
The St. Louis Cardinals traded Cliff Heathcote to the Chicago Cubs for Max Flack.
The Boston Braves signed Tim McNamara as an amateur free agent.
The New York Giants signed Clint Blume as a free agent.
The New York Giants purchased Travis Jackson from Little Rock (Southern Association).
The Detroit Tigers purchased Roy Moore from the Philadelphia Athletics.
The Philadelphia Phillies purchased Johnny Mokan from the Pittsburgh Pirates.
The Boston Braves purchased Gene Lansing from Charleston (South Atlantic).
The New York Yankees traded Chick Fewster, Elmer Miller, Johnny Mitchell, Lefty O'Doul and $50,000 to the Boston Red Sox for Joe Dugan and Elmer Smith.
The Boston Braves purchased Al Yeargin from Greenville (South Atlantic).
The New York Giants traded Larry Benton, Harry Hulihan, Fred Toney and $100,000 to the Boston Braves for Hugh McQuillan.
The Cincinnati Reds purchased Rube Benton from the New York Giants.
Toledo (American Association) traded Lee King to the New York Giants for Ralph Shinners. (Date given is approximate. Exact date is uncertain.)
The New York Giants signed Jack Scott as a free agent.
The Boston Braves purchased Snake Henry from New Orleans (Southern Association).
The Brooklyn Robins purchased Leo Dickerman from Memphis (Southern Association) for $10,000. (Date given is approximate. Exact date is uncertain.)
The St. Louis Browns selected Eddie Foster off waivers from the Boston Red Sox.
The St. Louis Cardinals selected Fred Toney off waivers from the Boston Braves.
The Cleveland Indians purchased Joe Connolly from Little Rock (Southern Association).
The Brooklyn Robins purchased Billy Mullen from Mobile (Southern Association). (Date given is approximate. Exact date is uncertain.)
Portland (PCL) purchased Jim Sullivan from the Philadelphia Athletics. (Date given is approximate. Exact date is uncertain.)
Portland (PCL) purchased Rube Yarrison from the Philadelphia Athletics. (Date given is approximate. Exact date is uncertain.)
The Boston Braves purchased Bunny Roser from St Petersburg (Florida State).
The Boston Braves purchased Gil Gallagher from Norfolk (Virginia).
The Boston Braves signed Joe Genewich as an amateur free agent.
The Boston Braves purchased Joe Matthews from Norfolk (Virginia).
The Chicago Cubs purchased George Grantham from Omaha (Western). (Date given is approximate. Exact date is uncertain.)
The Pittsburgh Pirates purchased Tom Lovelace from Dallas (Texas). (Date given is approximate. Exact date is uncertain.)
The Cleveland Indians purchased Homer Summa from Wichita Falls (Texas). (Date given is approximate. Exact date is uncertain.)
The Washington Senators purchased Rip Wade from Minneapolis (American Association). (Date given is approximate. Exact date is uncertain.)
The New York Giants purchased Rube Walberg from Portland (PCL). (Date given is approximate. Exact date is uncertain.)
The Cleveland Indians selected Sherry Smith off waivers from the Brooklyn Robins.
The Boston Braves drafted Bill Bagwell from Independence (Southwestern) in the 1922 rule 5 draft.
The Chicago Cubs drafted Bob Barrett from Little Rock (Southern Association) in the 1922 rule 5 draft.
The Boston Braves drafted Gus Felix from Shreveport (Texas) in the 1922 rule 5 draft.
The Brooklyn Robins drafted Charlie Hargreaves from Pittsfield (Eastern) in the 1922 rule 5 draft.
The Washington Senators drafted Pinky Hargrave from New Haven (Eastern) in the 1922 rule 5 draft.
The Boston Braves drafted Ernie Padgett from Memphis (Southern Association) in the 1922 rule 5 draft.
The Washington Senators drafted Squire Potter from Knoxville (Appalachian) in the 1922 rule 5 draft.
The Boston Braves drafted Bob Smith from New Orleans (Southern Association) in the 1922 rule 5 draft.
The Chicago Cubs drafted Ed Stauffer from Bridgeport (Eastern) in the 1922 rule 5 draft.
The Brooklyn Robins drafted Stuffy Stewart from Birmingham (Southern Association) in the 1922 rule 5 draft.
The Detroit Tigers selected Frank O'Rourke off waivers from the Boston Red Sox.
The Detroit Tigers traded Danny Clark, Howard Ehmke, Babe Herman, Carl Holling and $25,000 to the Boston Red Sox for Rip Collins and Del Pratt.
The New York Giants purchased Jack Bentley from Baltimore (International) for $72,000.
The Pittsburgh Pirates selected Jim Bagby off waivers from the Cleveland Indians.
The Philadelphia Athletics traded Frank Callaway, Dave Keefe and $20,000 to Milwaukee (American Association) for Wid Matthews.
The Washington Senators traded Ray Francis to the Detroit Tigers for Chick Gagnon.
The Philadelphia Athletics purchased Sammy Hale from Portland (PCL) for $40,000.
The Philadelphia Phillies purchased Walter Holke from the Boston Braves.
Toledo (American Association) purchased Walter Barbare from the Boston Braves.
Toledo (American Association) purchased Fred Nicholson from the Boston Red Sox.
The St. Louis Cardinals signed Chick Hafey as a free agent.
The Brooklyn Robins purchased Turner Barber from the Chicago Cubs.
The New York Yankees traded Al DeVormer and cash to the Boston Red Sox for Harvey Hendrick and George Pipgras.
The Washington Senators traded Frank Brower to the Cleveland Indians for Joe Evans.
The New York Yankees traded Norm McMillan, George Murray, Camp Skinner and $50,000 to the Boston Red Sox for Herb Pennock.
The Washington Senators traded Ed Goebel, Val Picinich and Howie Shanks to the Boston Red Sox for Muddy Ruel and Allen Russell.
The Philadelphia Phillies traded George Smith to the Brooklyn Robins for Clarence Mitchell.
The St. Louis Cardinals traded Jack Fournier to the Brooklyn Robins for Hy Myers and Ray Schmandt.
The Cleveland Indians released Stuffy McInnis.
The Boston Braves signed Stuffy McInnis as a free agent.