+ - Indicates Hall of Famer. Bold indicates active player.
Statistic Description: Win-Loss Percentage W / (W + L) For players, leaders need one decision for every ten team games. For managers, minimum to qualify for leading is 320 games.
Minimum of 1000 IP, 3000 PA, 500 games (fielding), 200 stolen base attempts (catchers) or 80 stolen base attempts (baserunners only since 1951) or 100 decisions for career and active leaderboards for rate statistics.
| Rank | Player (yrs, age) | Win-Loss % | Throws |
|---|---|---|---|
| 1. | Roy Halladay (16, 36) | .6590 | R |
| 2. | Jered Weaver (8, 30) | .6581 | R |
| 3. | Tim Hudson (15, 37) | .6547 | R |
| 4. | Justin Verlander (9, 30) | .6531 | R |
| 5. | Jon Lester (8, 29) | .6522 | L |
| 6. | CC Sabathia (13, 32) | .6500 | L |
| 7. | Johan Santana (12, 34) | .6406 | L |
| 8. | Andy Pettitte (18, 41) | .6336 | L |
| 9. | Adam Wainwright (8, 31) | .6296 | R |
| 10. | Clayton Kershaw (6, 25) | .6250 | L |
| 11. | Cliff Lee (12, 34) | .6172 | L |
| 12. | Yovani Gallardo (7, 27) | .6154 | R |
| 13. | Chris Carpenter (15, 38) | .6050 | R |
| 14. | Freddy Garcia (15, 36) | .5984 | R |
| 15. | Gio Gonzalez (6, 27) | .5962 | L |
| 16. | Cole Hamels (8, 29) | .5860 | L |
| 17. | Tim Lincecum (7, 29) | .5857 | R |
| 18. | Bartolo Colon (16, 40) | .5839 | R |
| 19. | Kyle Kendrick (7, 28) | .5743 | R |
| 20. | Jake Peavy (12, 32) | .5708 | R |
| 21. | Chad Billingsley (8, 28) | .5704 | R |
| 22. | Johnny Cueto (6, 27) | .5701 | R |
| 23. | Felix Hernandez (9, 27) | .5691 | R |
| 24. | Josh Beckett (13, 33) | .5690 | R |
| 25. | John Lackey (11, 34) | .5683 | R |
| 26. | Scott Baker (7, 31) | .5676 | R |
| 27. | Mariano Rivera (19, 43) | .5672 | R |
| 28. | Mark Buehrle (14, 34) | .5663 | L |
| 29. | C.J. Wilson (9, 32) | .5566 | L |
| 30. | Darren Oliver (20, 42) | .5519 | L |
| 31. | Dan Haren (11, 32) | .5491 | R |
| 32. | Barry Zito (14, 35) | .5488 | L |
| 33. | Ervin Santana (9, 30) | .5470 | R |
| 34. | Octavio Dotel (15, 39) | .5413 | R |
| 35. | Zack Greinke (10, 29) | .5412 | R |
| 36. | Joe Saunders (9, 32) | .5400 | L |
| 37. | James Shields (8, 31) | .5394 | R |
| 38. | Jose Contreras (11, 41) | .5379 | R |
| 39. | Ted Lilly (15, 37) | .5372 | L |
| 40. | Ricky Nolasco (8, 30) | .5306 | R |
| 41. | Derek Lowe (17, 40) | .5285 | R |
| 42. | A.J. Burnett (15, 36) | .5283 | R |
| 43. | Kelvim Escobar (12, 37) | .5260 | R |
| 44. | Jon Garland (13, 33) | .5253 | R |
| 45. | Esteban Loaiza (14, 41) | .5250 | R |
| 46. | Matt Cain (9, 28) | .5210 | R |
| 47. | Scott Kazmir (9, 29) | .5191 | L |
| 48. | Trevor Cahill (5, 25) | .5189 | R |
| 49. | Jorge De La Rosa (10, 32) | .5179 | L |
| 50. | Bronson Arroyo (14, 36) | .5163 | R |
| Rank | Player (yrs, age) | Win-Loss % | Throws |
| 51. | Ubaldo Jimenez (8, 29) | .5143 | R |
| 52. | Kyle Lohse (13, 34) | .5129 | R |
| 53. | Hiroki Kuroda (6, 38) | .5124 | R |
| 54. | R.A. Dickey (11, 38) | .5120 | R |
| 55. | Jason Marquis (14, 34) | .5110 | R |
| 56. | Jake Westbrook (13, 35) | .5102 | R |
| 57. | Bruce Chen (15, 36) | .5034 | L |
| 58. | Joe Blanton (10, 32) | .5030 | R |
| 59. | Ramon Ortiz (12, 40) | .5029 | R |
| 60. | Brett Myers (12, 32) | .5026 | R |
| 61. | Gavin Floyd (10, 30) | .5000 | R |
| Francisco Liriano (8, 29) | .5000 | L | |
| 63. | Ryan Dempster (16, 36) | .4961 | R |
| 64. | Aaron Harang (12, 35) | .4953 | R |
| 65. | Wandy Rodriguez (9, 34) | .4944 | L |
| 66. | Anibal Sanchez (8, 29) | .4906 | R |
| 67. | Aaron Cook (11, 34) | .4903 | R |
| 68. | Erik Bedard (10, 34) | .4884 | L |
| 69. | John Danks (6, 28) | .4872 | L |
| 70. | Kevin Correia (11, 32) | .4848 | R |
| 71. | Matt Garza (7, 29) | .4831 | R |
| 72. | Edwin Jackson (11, 29) | .4830 | R |
| 73. | Mike Pelfrey (8, 29) | .4818 | R |
| 74. | Rodrigo Lopez (11, 37) | .4765 | R |
| 75. | Jeff Francis (9, 32) | .4759 | L |
| 76. | Chris Capuano (9, 34) | .4730 | L |
| 77. | Miguel Batista (18, 42) | .4700 | R |
| 78. | Jeremy Bonderman (8, 30) | .4653 | R |
| 79. | Oliver Perez (11, 31) | .4504 | L |
| 80. | Justin Masterson (6, 28) | .4500 | R |
| 81. | Dave Bush (9, 33) | .4480 | R |
| 82. | Paul Maholm (9, 31) | .4430 | L |
| 83. | Mark Hendrickson (10, 39) | .4394 | L |
| 84. | Jeremy Guthrie (10, 34) | .4348 | R |
| 85. | Roberto Hernandez (8, 32) | .4297 | R |
| 86. | Nate Robertson (9, 35) | .4254 | L |
| 87. | LaTroy Hawkins (19, 40) | .4248 | R |
| 88. | Jamey Wright (18, 38) | .4186 | R |
| 89. | Kyle Farnsworth (15, 37) | .4038 | R |
| 90. | Kip Wells (12, 36) | .4012 | R |
| 91. | Zach Duke (9, 30) | .3984 | L |