+ - Indicates Hall of Famer. Bold indicates active player.
Statistic Description: Win-Loss Percentage W / (W + L) For players, leaders need one decision for every ten team games. For managers, minimum to qualify for leading is 320 games.
Minimum of 1000 IP, 3000 PA, 500 games (fielding), 200 stolen base attempts (catchers) or 80 stolen base attempts (baserunners only since 1951) or 100 decisions for career and active leaderboards for rate statistics.
| Rank | Player (yrs, age) | Win-Loss % | Throws |
|---|---|---|---|
| 1. | Roy Halladay (16, 36) | .6590 | R |
| 2. | Jered Weaver (8, 30) | .6581 | R |
| 3. | Tim Hudson (15, 37) | .6526 | R |
| 4. | Justin Verlander (9, 30) | .6515 | R |
| 5. | Jon Lester (8, 29) | .6500 | L |
| CC Sabathia (13, 32) | .6500 | L | |
| 7. | Johan Santana (12, 34) | .6406 | L |
| 8. | Andy Pettitte (18, 41) | .6320 | L |
| 9. | Clayton Kershaw (6, 25) | .6286 | L |
| 10. | Adam Wainwright (8, 31) | .6277 | R |
| 11. | Cliff Lee (12, 34) | .6190 | L |
| 12. | Chris Carpenter (15, 38) | .6050 | R |
| Yovani Gallardo (7, 27) | .6050 | R | |
| 14. | Gio Gonzalez (6, 27) | .5962 | L |
| 15. | Freddy Garcia (15, 36) | .5961 | R |
| 16. | Bartolo Colon (16, 40) | .5853 | R |
| 17. | Tim Lincecum (7, 29) | .5816 | R |
| 18. | Max Scherzer (6, 28) | .5800 | R |
| 19. | Cole Hamels (8, 29) | .5786 | L |
| 20. | Johnny Cueto (6, 27) | .5741 | R |
| 21. | Chad Billingsley (8, 28) | .5704 | R |
| 22. | John Lackey (11, 34) | .5702 | R |
| 23. | Josh Beckett (13, 33) | .5690 | R |
| 24. | Kyle Kendrick (7, 28) | .5686 | R |
| 25. | Jake Peavy (12, 32) | .5682 | R |
| 26. | Scott Baker (7, 31) | .5676 | R |
| 27. | Mariano Rivera (19, 43) | .5672 | R |
| 28. | Felix Hernandez (9, 27) | .5659 | R |
| 29. | Mark Buehrle (14, 34) | .5645 | L |
| 30. | C.J. Wilson (9, 32) | .5556 | L |
| 31. | Darren Oliver (20, 42) | .5519 | L |
| 32. | Barry Zito (14, 35) | .5470 | L |
| 33. | Dan Haren (11, 32) | .5467 | R |
| 34. | Ervin Santana (9, 30) | .5440 | R |
| 35. | Octavio Dotel (15, 39) | .5413 | R |
| 36. | Zack Greinke (10, 29) | .5407 | R |
| 37. | Joe Saunders (9, 32) | .5400 | L |
| 38. | Jose Contreras (11, 41) | .5379 | R |
| 39. | Ted Lilly (15, 37) | .5372 | L |
| 40. | Ricky Nolasco (8, 30) | .5338 | R |
| 41. | James Shields (8, 31) | .5329 | R |
| 42. | Derek Lowe (17, 40) | .5285 | R |
| 43. | A.J. Burnett (15, 36) | .5283 | R |
| 44. | Jorge De La Rosa (10, 32) | .5263 | L |
| 45. | Kelvim Escobar (12, 37) | .5260 | R |
| 46. | Esteban Loaiza (14, 41) | .5250 | R |
| 47. | Matt Cain (9, 28) | .5238 | R |
| 48. | Jon Garland (13, 33) | .5212 | R |
| 49. | Scott Kazmir (9, 29) | .5191 | L |
| 50. | Trevor Cahill (5, 25) | .5185 | R |
| Rank | Player (yrs, age) | Win-Loss % | Throws |
| 51. | Bronson Arroyo (14, 36) | .5182 | R |
| 52. | R.A. Dickey (11, 38) | .5159 | R |
| 53. | Jason Marquis (14, 34) | .5153 | R |
| 54. | Hiroki Kuroda (6, 38) | .5122 | R |
| 55. | Kyle Lohse (13, 34) | .5107 | R |
| 56. | Ubaldo Jimenez (8, 29) | .5106 | R |
| 57. | Jake Westbrook (13, 35) | .5102 | R |
| 58. | Francisco Liriano (8, 29) | .5091 | L |
| 59. | Bruce Chen (15, 36) | .5068 | L |
| 60. | Joe Blanton (10, 32) | .5030 | R |
| 61. | Ramon Ortiz (12, 40) | .5029 | R |
| 62. | Brett Myers (12, 32) | .5026 | R |
| 63. | Gavin Floyd (10, 30) | .5000 | R |
| Wandy Rodriguez (9, 34) | .5000 | L | |
| 65. | Ismael Valdez (12, 39) | .4976 | R |
| 66. | Ryan Dempster (16, 36) | .4961 | R |
| 67. | Aaron Harang (12, 35) | .4930 | R |
| 68. | Aaron Cook (11, 34) | .4903 | R |
| 69. | Erik Bedard (10, 34) | .4884 | L |
| 70. | John Danks (6, 28) | .4872 | L |
| 71. | Anibal Sanchez (8, 29) | .4860 | R |
| 72. | Matt Garza (8, 29) | .4831 | R |
| 73. | Kevin Correia (11, 32) | .4812 | R |
| 74. | Edwin Jackson (11, 29) | .4797 | R |
| 75. | Mike Pelfrey (8, 29) | .4775 | R |
| 76. | Rodrigo Lopez (11, 37) | .4765 | R |
| 77. | Jeff Francis (9, 32) | .4759 | L |
| 78. | Jason Hammel (8, 30) | .4752 | R |
| 79. | Chris Capuano (9, 34) | .4730 | L |
| 80. | Miguel Batista (18, 42) | .4700 | R |
| 81. | Jeremy Bonderman (8, 30) | .4653 | R |
| 82. | Justin Masterson (6, 28) | .4554 | R |
| 83. | Oliver Perez (11, 31) | .4511 | L |
| 84. | Paul Maholm (9, 31) | .4500 | L |
| 85. | Dave Bush (9, 33) | .4480 | R |
| 86. | Mark Hendrickson (10, 39) | .4394 | L |
| 87. | Jeremy Guthrie (10, 34) | .4317 | R |
| 88. | Roberto Hernandez (8, 32) | .4297 | R |
| 89. | Nate Robertson (9, 35) | .4254 | L |
| 90. | LaTroy Hawkins (19, 40) | .4248 | R |
| 91. | Jamey Wright (18, 38) | .4186 | R |
| 92. | Kyle Farnsworth (15, 37) | .4038 | R |
| 93. | Kip Wells (12, 36) | .4012 | R |
| 94. | Kyle Davies (7, 29) | .3981 | R |
| 95. | Zach Duke (9, 30) | .3952 | L |