+ - Indicates Hall of Famer. Bold indicates active player.
Statistic Description: Win-Loss Percentage W / (W + L) For players, leaders need one decision for every ten team games. For managers, minimum to qualify for leading is 320 games.
Minimum of 1000 IP, 3000 PA, 500 games (fielding), 200 stolen base attempts (catchers) or 80 stolen base attempts (baserunners only since 1951) or 100 decisions for career and active leaderboards for rate statistics.
| Rank | Player (yrs, age) | Win-Loss % | Throws |
|---|---|---|---|
| 1. | Roy Halladay (16, 36) | .6590 | R |
| 2. | Jered Weaver (8, 30) | .6581 | R |
| 3. | Tim Hudson (15, 37) | .6526 | R |
| 4. | Justin Verlander (9, 30) | .6515 | R |
| 5. | Jon Lester (8, 29) | .6500 | L |
| CC Sabathia (13, 32) | .6500 | L | |
| 7. | Johan Santana (12, 34) | .6406 | L |
| 8. | Andy Pettitte (18, 41) | .6320 | L |
| 9. | Roy Oswalt (12, 35) | .6293 | R |
| 10. | Clayton Kershaw (6, 25) | .6286 | L |
| 11. | Adam Wainwright (8, 31) | .6277 | R |
| 12. | Cliff Lee (12, 34) | .6190 | L |
| 13. | Chris Carpenter (15, 38) | .6050 | R |
| Yovani Gallardo (7, 27) | .6050 | R | |
| 15. | Gio Gonzalez (6, 27) | .5962 | L |
| 16. | Freddy Garcia (15, 36) | .5961 | R |
| 17. | Bartolo Colon (16, 40) | .5853 | R |
| 18. | Max Scherzer (6, 28) | .5800 | R |
| 19. | Cole Hamels (8, 29) | .5786 | L |
| 20. | Tim Lincecum (7, 29) | .5775 | R |
| 21. | Johnny Cueto (6, 27) | .5741 | R |
| 22. | John Lackey (11, 34) | .5721 | R |
| 23. | Chad Billingsley (8, 28) | .5704 | R |
| 24. | Josh Beckett (13, 33) | .5690 | R |
| 25. | Jake Peavy (12, 32) | .5682 | R |
| 26. | Scott Baker (7, 31) | .5676 | R |
| 27. | Mariano Rivera (19, 43) | .5672 | R |
| 28. | Felix Hernandez (9, 27) | .5659 | R |
| 29. | Mark Buehrle (14, 34) | .5645 | L |
| 30. | Kyle Kendrick (7, 28) | .5631 | R |
| 31. | C.J. Wilson (9, 32) | .5556 | L |
| 32. | Darren Oliver (20, 42) | .5519 | L |
| 33. | Barry Zito (14, 35) | .5470 | L |
| 34. | Dan Haren (11, 32) | .5467 | R |
| 35. | Octavio Dotel (15, 39) | .5413 | R |
| 36. | Ervin Santana (9, 30) | .5410 | R |
| 37. | Zack Greinke (10, 29) | .5407 | R |
| 38. | Jose Contreras (11, 41) | .5379 | R |
| 39. | Ted Lilly (15, 37) | .5372 | L |
| 40. | Joe Saunders (9, 32) | .5364 | L |
| 41. | Ricky Nolasco (8, 30) | .5338 | R |
| 42. | James Shields (8, 31) | .5329 | R |
| 43. | Derek Lowe (17, 40) | .5285 | R |
| 44. | A.J. Burnett (15, 36) | .5263 | R |
| Jorge De La Rosa (10, 32) | .5263 | L | |
| 46. | Kelvim Escobar (12, 37) | .5260 | R |
| 47. | Esteban Loaiza (14, 41) | .5250 | R |
| 48. | Matt Cain (9, 28) | .5238 | R |
| 49. | Jon Garland (13, 33) | .5212 | R |
| 50. | Bronson Arroyo (14, 36) | .5202 | R |
| Rank | Player (yrs, age) | Win-Loss % | Throws |
| 51. | Scott Kazmir (9, 29) | .5191 | L |
| 52. | Trevor Cahill (5, 25) | .5185 | R |
| 53. | R.A. Dickey (11, 38) | .5159 | R |
| 54. | Jason Marquis (14, 34) | .5153 | R |
| 55. | Hiroki Kuroda (6, 38) | .5122 | R |
| 56. | Kyle Lohse (13, 34) | .5107 | R |
| 57. | Ubaldo Jimenez (8, 29) | .5106 | R |
| 58. | Jake Westbrook (13, 35) | .5102 | R |
| 59. | Francisco Liriano (8, 29) | .5091 | L |
| 60. | Bruce Chen (15, 36) | .5068 | L |
| 61. | Joe Blanton (10, 32) | .5060 | R |
| 62. | Ramon Ortiz (12, 40) | .5029 | R |
| 63. | Brett Myers (12, 32) | .5026 | R |
| 64. | Gavin Floyd (10, 30) | .5000 | R |
| Wandy Rodriguez (9, 34) | .5000 | L | |
| 66. | Ismael Valdez (12, 39) | .4976 | R |
| 67. | Ryan Dempster (16, 36) | .4941 | R |
| 68. | Aaron Harang (12, 35) | .4930 | R |
| 69. | Anibal Sanchez (8, 29) | .4907 | R |
| 70. | Aaron Cook (11, 34) | .4903 | R |
| 71. | Erik Bedard (10, 34) | .4884 | L |
| 72. | John Danks (7, 28) | .4872 | L |
| 73. | Matt Garza (8, 29) | .4831 | R |
| 74. | Kevin Correia (11, 32) | .4812 | R |
| 75. | Mike Pelfrey (8, 29) | .4775 | R |
| 76. | Edwin Jackson (11, 29) | .4765 | R |
| Rodrigo Lopez (11, 37) | .4765 | R | |
| 78. | Jeff Francis (9, 32) | .4759 | L |
| 79. | Jason Hammel (8, 30) | .4752 | R |
| 80. | Miguel Batista (18, 42) | .4700 | R |
| 81. | Chris Capuano (9, 34) | .4698 | L |
| 82. | Jeremy Bonderman (8, 30) | .4653 | R |
| 83. | Oliver Perez (11, 31) | .4511 | L |
| 84. | Justin Masterson (6, 28) | .4510 | R |
| 85. | Paul Maholm (9, 31) | .4500 | L |
| 86. | Dave Bush (9, 33) | .4480 | R |
| 87. | Mark Hendrickson (10, 39) | .4394 | L |
| 88. | Jeremy Guthrie (10, 34) | .4317 | R |
| 89. | Roberto Hernandez (8, 32) | .4264 | R |
| 90. | Nate Robertson (9, 35) | .4254 | L |
| 91. | LaTroy Hawkins (19, 40) | .4248 | R |
| 92. | Jamey Wright (18, 38) | .4186 | R |
| 93. | Kyle Farnsworth (15, 37) | .4038 | R |
| 94. | Kip Wells (12, 36) | .4012 | R |
| 95. | Kyle Davies (7, 29) | .3981 | R |
| 96. | Zach Duke (9, 30) | .3952 | L |