+ - Indicates Hall of Famer. Bold indicates active player.
Statistic Description: ERA+ 100*[lgERA/ERA] Adjusted to the players ballpark(s).
Minimum of 1000 IP, 3000 PA, 500 games (fielding), 200 stolen base attempts (catchers) or 80 stolen base attempts (baserunners only since 1951) or 100 decisions for career and active leaderboards for rate statistics.
| Rank | Player (yrs, age) | Adjusted ERA+ | Throws |
|---|---|---|---|
| 1. | Mariano Rivera (19, 43) | 206 | R |
| 2. | Clayton Kershaw (6, 25) | 142 | L |
| 3. | Johan Santana (12, 34) | 136 | L |
| 4. | Roy Halladay (16, 36) | 131 | R |
| Adam Wainwright (8, 31) | 131 | R | |
| 6. | Felix Hernandez (9, 27) | 130 | R |
| Justin Verlander (9, 30) | 130 | R | |
| 8. | Jered Weaver (8, 30) | 128 | R |
| 9. | Cole Hamels (8, 29) | 125 | L |
| Tim Hudson (15, 37) | 125 | R | |
| CC Sabathia (13, 32) | 125 | L | |
| 12. | Matt Cain (9, 28) | 122 | R |
| 13. | Jon Lester (8, 29) | 121 | L |
| 14. | Tim Lincecum (7, 29) | 119 | R |
| 15. | Cliff Lee (12, 34) | 118 | L |
| 16. | Mark Buehrle (14, 34) | 117 | L |
| Jake Peavy (12, 32) | 117 | R | |
| Andy Pettitte (18, 41) | 117 | L | |
| 19. | Chris Carpenter (15, 38) | 116 | R |
| 20. | Zack Greinke (10, 29) | 115 | R |
| 21. | Dan Haren (11, 32) | 114 | R |
| 22. | Kelvim Escobar (12, 37) | 112 | R |
| 23. | Josh Beckett (13, 33) | 111 | R |
| Bartolo Colon (16, 40) | 111 | R | |
| 25. | Erik Bedard (10, 34) | 110 | L |
| Chad Billingsley (8, 28) | 110 | R | |
| Ubaldo Jimenez (8, 29) | 110 | R | |
| 28. | Derek Lowe (17, 40) | 109 | R |
| Barry Zito (14, 35) | 109 | L | |
| 30. | Freddy Garcia (15, 36) | 108 | R |
| Matt Garza (7, 29) | 108 | R | |
| James Shields (8, 31) | 108 | R | |
| 33. | John Lackey (11, 34) | 107 | R |
| 34. | Ted Lilly (15, 37) | 106 | L |
| 35. | A.J. Burnett (15, 36) | 105 | R |
| 36. | Bronson Arroyo (14, 36) | 104 | R |
| R.A. Dickey (11, 38) | 104 | R | |
| Jon Garland (13, 33) | 104 | R | |
| Jeremy Guthrie (10, 34) | 104 | R | |
| LaTroy Hawkins (19, 40) | 104 | R | |
| Scott Kazmir (9, 29) | 104 | L | |
| Darren Oliver (20, 42) | 104 | L | |
| 43. | Aaron Cook (11, 34) | 103 | R |
| 44. | Wandy Rodriguez (9, 34) | 102 | L |
| 45. | Jose Contreras (11, 41) | 101 | R |
| Joe Saunders (9, 32) | 101 | L | |
| 47. | Miguel Batista (18, 42) | 100 | R |
| Gavin Floyd (10, 30) | 100 | R | |
| Aaron Harang (12, 35) | 100 | R | |
| 50. | Ryan Dempster (16, 36) | 99 | R |
| Rank | Player (yrs, age) | Adjusted ERA+ | Throws |
| Brett Myers (12, 32) | 99 | R | |
| Jake Westbrook (13, 35) | 99 | R | |
| 53. | Esteban Loaiza (14, 41) | 98 | R |
| Ervin Santana (9, 30) | 98 | R | |
| 55. | Chris Capuano (9, 34) | 97 | L |
| Kyle Lohse (13, 34) | 97 | R | |
| Paul Maholm (9, 31) | 97 | L | |
| 58. | Jeff Francis (9, 32) | 96 | L |
| Edwin Jackson (11, 29) | 96 | R | |
| Jamey Wright (18, 38) | 96 | R | |
| 61. | Joe Blanton (10, 32) | 95 | R |
| Bruce Chen (15, 36) | 95 | L | |
| Jason Marquis (14, 34) | 95 | R | |
| 64. | Kip Wells (12, 36) | 94 | R |
| 65. | Dave Bush (9, 33) | 92 | R |
| Zach Duke (9, 30) | 92 | L | |
| Ricky Nolasco (8, 30) | 92 | R | |
| Oliver Perez (11, 31) | 92 | L | |
| 69. | Rodrigo Lopez (11, 37) | 91 | R |
| 70. | Jeremy Bonderman (8, 30) | 90 | R |
| Ramon Ortiz (12, 40) | 90 | R | |
| 72. | Kevin Correia (11, 32) | 89 | R |
| Mark Hendrickson (10, 39) | 89 | L | |
| 74. | Nate Robertson (9, 35) | 88 | L |