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Active Leaders & Records for Strikeouts
+ - Indicates Hall of Famer. Bold indicates active player.
| Rank | Player (age) | Strikeouts | Bats |
|---|---|---|---|
| 1. | Jim Thome (38) | 2258 | L |
| 2. | Carlos Delgado (37) | 1745 | L |
| 3. | Mike Cameron (36) | 1721 | R |
| Ken Griffey (39) | 1721 | L | |
| 5. | Manny Ramirez (37) | 1686 | R |
| 6. | Alex Rodriguez (33) | 1674 | R |
| 7. | Jim Edmonds (39) | 1669 | L |
| 8. | Andruw Jones (32) | 1510 | R |
| 9. | Bobby Abreu (35) | 1458 | L |
| 10. | Derek Jeter (35) | 1417 | R |
| 11. | Jason Giambi (38) | 1376 | L |
| 12. | Adam Dunn (29) | 1352 | L |
| 13. | Ivan Rodriguez (37) | 1339 | R |
| 14. | Derrek Lee (33) | 1326 | R |
| 15. | Pat Burrell (32) | 1320 | R |
| 16. | Richie Sexson (34) | 1313 | R |
| 17. | Troy Glaus (32) | 1269 | R |
| 18. | Jermaine Dye (35) | 1260 | R |
| 19. | Jorge Posada (37) | 1221 | B |
| 20. | Luis Gonzalez (41) | 1218 | L |
| 21. | Tony Clark (37) | 1208 | B |
| 22. | Ray Durham (37) | 1201 | B |
| Scott Rolen (34) | 1201 | R | |
| 24. | Geoff Jenkins (34) | 1186 | L |
| 25. | Chipper Jones (37) | 1179 | B |
| 26. | Gary Sheffield (40) | 1161 | R |
| 27. | Alfonso Soriano (33) | 1149 | R |
| 28. | Garret Anderson (37) | 1148 | L |
| 29. | Jose Cruz (35) | 1147 | B |
| 30. | Preston Wilson (34) | 1085 | R |
| 31. | Carlos Beltran (32) | 1077 | B |
| 32. | Jason Varitek (37) | 1072 | B |
| 33. | Cliff Floyd (36) | 1064 | L |
| 34. | Adrian Beltre (30) | 1058 | R |
| 35. | Matt Stairs (41) | 1054 | L |
| 36. | Edgar Renteria (33) | 1049 | R |
| 37. | David Ortiz (33) | 1044 | L |
| 38. | Torii Hunter (33) | 1029 | R |
| 39. | Lance Berkman (33) | 1011 | B |
| 40. | Brad Ausmus (40) | 1008 | R |
| 41. | Johnny Damon (35) | 1007 | L |
| 42. | Omar Vizquel (42) | 987 | B |
| 43. | Jose Guillen (33) | 982 | R |
| 44. | Jacque Jones (34) | 949 | L |
| 45. | Brad Wilkerson (32) | 947 | L |
| 46. | Mark Grudzielanek (39) | 944 | R |
| 47. | Paul Konerko (33) | 943 | R |
| 48. | Randy Winn (35) | 937 | B |
| 49. | J.D. Drew (33) | 936 | L |
| 50. | Miguel Tejada (35) | 930 | R |
| Rank | Player (age) | Strikeouts | Bats |
| 51. | Darin Erstad (35) | 925 | L |
| Rondell White (37) | 925 | R | |
| 53. | Carlos Pena (31) | 919 | L |
| 54. | Moises Alou (42) | 894 | R |
| 55. | Eric Chavez (31) | 891 | L |
| 56. | Russell Branyan (33) | 888 | L |
| Brandon Inge (32) | 888 | R | |
| 58. | Dmitri Young (35) | 871 | B |
| 59. | Todd Helton (35) | 857 | L |
| 60. | Rich Aurilia (37) | 856 | R |
| 61. | Michael Young (32) | 854 | R |
| 62. | Juan Encarnacion (33) | 853 | R |
| 63. | Melvin Mora (37) | 841 | R |
| 64. | Alex Gonzalez (32) | 840 | R |
| 65. | Vladimir Guerrero (34) | 838 | R |
| 66. | Raul Ibanez (37) | 836 | L |
| 67. | Brian Giles (38) | 835 | L |
| 68. | Kevin Millar (37) | 820 | R |
| 69. | Jason Bay (30) | 817 | R |
| 70. | Casey Blake (35) | 792 | R |
| Carlos Lee (33) | 792 | R | |
| 72. | Ryan Howard (29) | 791 | L |
| 73. | Tony Batista (35) | 790 | R |
| 74. | Julio Lugo (33) | 788 | R |
| Gary Matthews (34) | 788 | B | |
| 76. | Luis Castillo (33) | 785 | B |
| 77. | Corey Patterson (29) | 774 | L |
| 78. | Miguel Cabrera (26) | 767 | R |
| 79. | Aramis Ramirez (31) | 765 | R |
| 80. | Mike Lowell (35) | 755 | R |
| 81. | Felipe Lopez (29) | 753 | B |
| 82. | Magglio Ordonez (35) | 752 | R |
| 83. | Chris Gomez (38) | 750 | R |
| 84. | Mark Teixeira (29) | 748 | B |
| 85. | Jason LaRue (35) | 742 | R |
| 86. | Bill Hall (29) | 739 | R |
| 87. | Jimmy Rollins (30) | 734 | B |
| 88. | Ron Belliard (34) | 730 | R |
| 89. | Mark Bellhorn (34) | 723 | B |
| 90. | Eric Hinske (31) | 721 | L |
| 91. | David Dellucci (35) | 712 | L |
| 92. | Rafael Furcal (31) | 707 | B |
| 93. | Carlos Guillen (33) | 706 | B |
| 94. | Aaron Boone (36) | 705 | R |
| 95. | Aaron Rowand (31) | 704 | R |
| 96. | Juan Uribe (29) | 700 | R |
| 97. | Jhonny Peralta (27) | 691 | R |
| 98. | Trot Nixon (35) | 689 | L |
| 99. | Cristian Guzman (31) | 688 | B |
| 100. | Shannon Stewart (35) | 684 | R |
