| 2011 | 1 | | 2 | FrRnd | 2 | Mariners | Danny Hultzen (minors) | | | | | | | | | | | | | 4Yr | University of Virginia (Charlottesville, VA) |
| 2011 | 1s | | 15 | FrRnd | 15 | Brewers | *Jed Bradley (minors) | | | | | | | | | | | | | 4Yr | Georgia Institute of Technology (Atlanta, GA) |
| 2011 | 1 | | 16 | FrRnd | 16 | Dodgers | Chris Reed (minors) | | | | | | | | | | | | | 4Yr | Stanford University (Palo Alto, CA) |
| 2011 | 1 | | 20 | FrRnd | 20 | Rockies | Tyler Anderson (minors) | | | | | | | | | | | | | 4Yr | University of Oregon (Eugene, OR) |
| 2011 | 1 | | 28 | FrRnd | 28 | Braves | Sean Gilmartin (minors) | | | | | | | | | | | | | 4Yr | Florida State University (Tallahassee, FL) |
| 2011 | 1 | | 33 | FrRnd | 33 | Rangers via Phillies | *Kevin Matthews (minors) | | | | | | | | | | | | | HS | Richmond Hill HS (Richmond Hill, GA) |
| 2011 | 1s | | 36 | FrRnd | 36 | Red Sox | *Henry Owens (minors) | | | | | | | | | | | | | HS | Edison HS (Huntington Beach, CA) |
| 2011 | 1s | | 43 | FrRnd | 43 | Diamondbacks | *Andrew Chafin (minors) | | | | | | | | | | | | | 4Yr | Kent State University (Kent, OH) |
| 2011 | 1s | | 52 | FrRnd | 52 | Rays | *Blake Snell (minors) | | | | | | | | | | | | | HS | Shorewood HS (Shoreline, WA) |
| 2011 | 1s | | 59 | FrRnd | 59 | Rays | *Grayson Garvin (minors) | | | | | | | | | | | | | 4Yr | Vanderbilt University (Nashville, TN) |
| 2011 | 2 | | 72 | FrRnd | 12 | Marlins | Adam Conley (minors) | | | | | | | | | | | | | 4Yr | Washington State University (Pullman, WA) |
| 2011 | 2 | | 74 | FrRnd | 14 | Blue Jays via Angels | *Daniel Norris (minors) | | | | | | | | | | | | | HS | Science Hill HS (Johnson City, TN) |
| 2011 | 2 | | 83 | FrRnd | 23 | Rangers | Will Lamb (minors) | | | | | | | | | | | | | 4Yr | Clemson University (Clemson, SC) |
| 2011 | 2 | | 88 | FrRnd | 28 | Yankees | Sam Stafford (minors) | | | | | | | | | | | | | 4Yr | University of Texas at Austin (Austin, TX) |
| 2011 | 3 | | 96 | FrRnd | 6 | Nationals | Matt Purke (minors) | | | | | | | | | | | | | 4Yr | Texas Christian University (Fort Worth, TX) |
| 2011 | 3 | | 104 | FrRnd | 14 | Angels | Nick Maronde (minors) | 0.1 | 15 | 0 | 0 | | | 15 | 0 | 0 | 4.32 | 1.68 | 0 | 4Yr | University of Florida (Gainesville, FL) |
| 2011 | 3 | | 114 | FrRnd | 24 | Reds | Tony Cingrani (minors) | 0.7 | 9 | 11 | 0 | .091 | .182 | 9 | 2 | 0 | 3.08 | 1.05 | 0 | 4Yr | Rice University (Houston, TX) |
| 2011 | 3 | | 117 | FrRnd | 27 | Twins | Corey Williams (minors) | | | | | | | | | | | | | 4Yr | Vanderbilt University (Nashville, TN) |
| 2011 | 3 | | 120 | FrRnd | 30 | Phillies | Adam Morgan (minors) | | | | | | | | | | | | | 4Yr | University of Alabama (Tuscaloosa, AL) |
| 2011 | 4 | | 127 | FrRnd | 6 | Nationals | Kylin Turnbull (minors) | | | | | | | | | | | | | JC | Santa Barbara City College (Santa Barbara, CA) |
| 2011 | 4 | | 130 | FrRnd | 9 | Astros | Christopher Lee (minors) | | | | | | | | | | | | | JC | Santa Fe Community College (Gainesville, FL) |
| 2011 | 4 | | 147 | FrRnd | 26 | Giants | Bryce Bandilla (minors) | | | | | | | | | | | | | 4Yr | University of Arizona (Tucson, AZ) |
| 2011 | 5 | | 155 | FrRnd | 4 | Orioles | Matt Taylor (minors) | | | | | | | | | | | | | JC | Middle Georgia College (Cochran, GA) |
| 2011 | 5 | | 162 | FrRnd | 11 | Mets | Jack Leathersich (minors) | | | | | | | | | | | | | 4Yr | University of Massachusetts Lowell (Lowell, MA) |
| 2011 | 5 | | 169 | FrRnd | 18 | Blue Jays | Andrew Chin (minors) | | | | | | | | | | | | | HS | Buckingham Browne & Nichols HS (Cambridge, MA) |
| 2011 | 5 | | 171 | FrRnd | 20 | White Sox | Scott Snodgress (minors) | | | | | | | | | | | | | 4Yr | Stanford University (Palo Alto, CA) |
| 2011 | 6 | | 186 | FrRnd | 5 | Royals | Cesar Ogando (minors) | | | | | | | | | | | | | JC | Caribbean University (Bayamon, PR) |
| 2011 | 6 | | 193 | FrRnd | 12 | Marlins | Charlie Lowell (minors) | | | | | | | | | | | | | 4Yr | Wichita State University (Wichita, KS) |
| 2011 | 6 | | 202 | FrRnd | 21 | Red Sox | Miguel Pena (minors) | | | | | | | | | | | | | JC | San Jacinto College North (Houston, TX) |
| 2011 | 6 | | 207 | FrRnd | 26 | Giants | Josh Osich (minors) | | | | | | | | | | | | | 4Yr | Oregon State University (Corvallis, OR) |
| 2011 | 7 | | 215 | FrRnd | 4 | Orioles | Trent Howard (minors) | | | | | | | | | | | | | 4Yr | Central Michigan University (Mount Pleasant, MI) |
| 2011 | 7 | | 227 | FrRnd | 16 | Tigers | Brian Flynn (minors) | | | | | | | | | | | | | 4Yr | Wichita State University (Wichita, KS) |
| 2011 | 7 | | 232 | FrRnd | 21 | Red Sox | Cody Kukuk (minors) | | | | | | | | | | | | | HS | Free State HS (Lawrence, KS) |
| 2011 | 7 | | 238 | FrRnd | 27 | Twins | Steven Gruver (minors) | | | | | | | | | | | | | 4Yr | University of Tennessee (Knoxville, TN) |
| 2011 | 7 | | 240 | FrRnd | 29 | Rays | Ryan Carpenter (minors) | | | | | | | | | | | | | 4Yr | Gonzaga University (Spokane, WA) |
| 2011 | 8 | | 248 | FrRnd | 7 | Indians | Stephen Tarpley (minors) | | | | | | | | | | | | | HS | Gilbert HS (Gilbert, AZ) |
| 2011 | 8 | | 254 | FrRnd | 13 | Dodgers | Rick Anton (minors) | | | | | | | | | | | | | 4Yr | University of Utah (Salt Lake City, UT) |
| 2011 | 8 | | 258 | FrRnd | 17 | Rockies | Roberto Padilla (minors) | | | | | | | | | | | | | 4Yr | San Jose State University (San Jose, CA) |
| 2011 | 8 | | 260 | FrRnd | 19 | Cardinals | Danny Miranda (minors) | | | | | | | | | | | | | 4Yr | University of Miami (Coral Gables, FL) |
| 2011 | 8 | | 268 | FrRnd | 27 | Twins | Jason Wheeler (minors) | | | | | | | | | | | | | 4Yr | Loyola Marymount University (Los Angeles, CA) |
| 2011 | 8 | | 271 | FrRnd | 30 | Phillies | Austin Wright (minors) | | | | | | | | | | | | | 4Yr | University of Mississippi (Oxford, MS) |
| 2011 | 9 | | 282 | FrRnd | 11 | Mets | Alex Panteliodis (minors) | | | | | | | | | | | | | 4Yr | University of Florida (Gainesville, FL) |
| 2011 | 9 | | 286 | FrRnd | 15 | Athletics | Jace Fry (minors) | | | | | | | | | | | | | HS | Southridge HS (Beaverton, OR) |
| 2011 | 9 | | 289 | FrRnd | 18 | Blue Jays | Andrew Suarez (minors) | | | | | | | | | | | | | HS | Christopher Columbus HS (Miami, FL) |
| 2011 | 9 | | 291 | FrRnd | 20 | White Sox | Matthew Lane (minors) | | | | | | | | | | | | | JC | Northwest Florida State College (Niceville, FL) |
| 2011 | 10 | | 310 | FrRnd | 9 | Astros | Kyle Hallock (minors) | | | | | | | | | | | | | 4Yr | Kent State University (Kent, OH) |
| 2011 | 10 | | 311 | FrRnd | 10 | Brewers | Michael Strong (minors) | | | | | | | | | | | | | 4Yr | Oklahoma State University (Stillwater, OK) |
| 2011 | 10 | | 314 | FrRnd | 13 | Dodgers | Jamaal Moore (minors) | | | | | | | | | | | | | HS | Westchester HS (Los Angeles, CA) |
| 2011 | 10 | | 321 | FrRnd | 20 | White Sox | Ben O'Shea (minors) | | | | | | | | | | | | | JC | Santa Fe Community College (Gainesville, FL) |
| 2011 | 10 | | 328 | FrRnd | 27 | Twins | Brett Lee (minors) | | | | | | | | | | | | | JC | St. Petersburg College (St. Petersburg, FL) |
| 2011 | 11 | | 333 | FrRnd | 2 | Mariners | Cam Hobson (minors) | | | | | | | | | | | | | 4Yr | University of Dayton (Dayton, OH) |
| 2011 | 11 | | 334 | FrRnd | 3 | Diamondbacks | Will Locante (minors) | | | | | | | | | | | | | 4Yr | Cumberland University (Lebanon, TN) |
| 2011 | 11 | | 345 | FrRnd | 14 | Angels | Garrett Baker (minors) | | | | | | | | | | | | | 4Yr | Liberty University (Lynchburg, VA) |
| 2011 | 11 | | 346 | FrRnd | 15 | Athletics | Chris Lamb (minors) | | | | | | | | | | | | | 4Yr | Davidson College (Davidson, NC) |
| 2011 | 11 | | 351 | FrRnd | 20 | White Sox | Blair Walters (minors) | | | | | | | | | | | | | 4Yr | University of Hawaii at Manoa (Honolulu, HI) |
| 2011 | 11 | | 352 | FrRnd | 21 | Red Sox | Kevin Brahney (minors) | | | | | | | | | | | | | 4Yr | California State University Chico (Chico, CA) |
| 2011 | 12 | | 366 | FrRnd | 5 | Royals | Adam Schemenauer (minors) | | | | | | | | | | | | | HS | Park Hill South HS (Kansas City, MO) |
| 2011 | 12 | | 367 | FrRnd | 6 | Nationals | Blake Monar (minors) | | | | | | | | | | | | | 4Yr | Indiana University-Bloomington (Bloomington, IN) |
| 2011 | 12 | | 369 | FrRnd | 8 | Cubs | Jacob Lindgren (minors) | | | | | | | | | | | | | HS | St. Stanislaus HS (Bay St. Louis, MS) |
| 2011 | 12 | | 372 | FrRnd | 11 | Mets | Kent Mathews (minors) | | | | | | | | | | | | | HS | Diamond Bar HS (Diamond Bar, CA) |
| 2011 | 12 | | 384 | FrRnd | 23 | Rangers | Gregory Williams (minors) | | | | | | | | | | | | | 4Yr | Marshall University (Huntington, WV) |
| 2011 | 12 | | 386 | FrRnd | 25 | Braves | Matt Chaffee (minors) | | | | | | | | | | | | | 4Yr | University of Arizona (Tucson, AZ) |
| 2011 | 13 | | 394 | FrRnd | 3 | Diamondbacks | John Pedrotty (minors) | | | | | | | | | | | | | 4Yr | College of the Holy Cross (Worcester, MA) |
| 2011 | 13 | | 396 | FrRnd | 5 | Royals | Stephen Lumpkins (minors) | | | | | | | | | | | | | 4Yr | American University (Washington, DC) |
| 2011 | 13 | | 408 | FrRnd | 17 | Rockies | Kyle Roliard (minors) | | | | | | | | | | | | | 4Yr | Louisiana Tech University (Ruston, LA) |
| 2011 | 13 | | 418 | FrRnd | 27 | Twins | Steven Evans (minors) | | | | | | | | | | | | | 4Yr | Liberty University (Lynchburg, VA) |
| 2011 | 14 | | 444 | FrRnd | 23 | Rangers | Andrew Faulkner (minors) | | | | | | | | | | | | | HS | South Aiken HS (Aiken, SC) |
| 2011 | 14 | | 448 | FrRnd | 27 | Twins | Adam McCreery (minors) | | | | | | | | | | | | | HS | Bonita HS (La Verne, CA) |
| 2011 | 15 | | 455 | FrRnd | 4 | Orioles | Eric Wooten (minors) | | | | | | | | | | | | | JC | Central Arizona College (Coolidge, AZ) |
| 2011 | 15 | | 469 | FrRnd | 18 | Blue Jays | Cody Glenn (minors) | | | | | | | | | | | | | HS | Westbury Christian School (Houston, TX) |
| 2011 | 15 | | 478 | FrRnd | 27 | Twins | Josue Montanez (minors) | | | | | | | | | | | | | JC | Miami Dade South CC (Miami, FL) |
| 2011 | 16 | | 482 | FrRnd | 1 | Pirates | Eric Skoglund (minors) | | | | | | | | | | | | | HS | Sarasota HS (Sarasota, FL) |
| 2011 | 16 | | 484 | FrRnd | 3 | Diamondbacks | Michael Blake (minors) | | | | | | | | | | | | | 4Yr | University of Hawaii at Manoa (Honolulu, HI) |
| 2011 | 16 | | 488 | FrRnd | 7 | Indians | Ryan Merritt (minors) | | | | | | | | | | | | | JC | McLennan Community College (Waco, TX) |
| 2011 | 16 | | 490 | FrRnd | 9 | Astros | Scott Zuloaga (minors) | | | | | | | | | | | | | JC | Scottsdale Community College (Scottsdale, AZ) |
| 2011 | 16 | | 491 | FrRnd | 10 | Brewers | Carlos Rodon (minors) | | | | | | | | | | | | | HS | Holly Springs HS (Holly Springs, NC) |
| 2011 | 16 | | 508 | FrRnd | 27 | Twins | Austin Malinowski (minors) | | | | | | | | | | | | | HS | Centennial HS (Circle Pines, MN) |
| 2011 | 17 | | 514 | FrRnd | 3 | Diamondbacks | Adam Choplick (minors) | | | | | | | | | | | | | HS | Billy Ryan HS (Denton, TX) |
| 2011 | 18 | | 542 | FrRnd | 1 | Pirates | Josh Poytress (minors) | | | | | | | | | | | | | 4Yr | California State University Fresno (Fresno, CA) |
| 2011 | 18 | | 543 | FrRnd | 2 | Mariners | Nick Valenza (minors) | | | | | | | | | | | | | HS | Horizon HS (Scottsdale, AZ) |
| 2011 | 18 | | 544 | FrRnd | 3 | Diamondbacks | Taylor Siemens (minors) | | | | | | | | | | | | | 4Yr | California Baptist University (Riverside, CA) |
| 2011 | 18 | | 547 | FrRnd | 6 | Nationals | Nicholas Lee (minors) | | | | | | | | | | | | | JC | Weatherford College (Weatherford, TX) |
| 2011 | 18 | | 553 | FrRnd | 12 | Marlins | Gregory Nappo (minors) | | | | | | | | | | | | | 4Yr | University of Connecticut (Storrs, CT) |
| 2011 | 18 | | 556 | FrRnd | 15 | Athletics | Brent Powers (minors) | | | | | | | | | | | | | 4Yr | Sam Houston State University (Huntsville, TX) |
| 2011 | 18 | | 560 | FrRnd | 19 | Cardinals | Kyle Hald (minors) | | | | | | | | | | | | | 4Yr | Old Dominion University (Norfolk, VA) |
| 2011 | 18 | | 568 | FrRnd | 27 | Twins | Corey Kimes (minors) | | | | | | | | | | | | | 4Yr | University of Illinois at Urbana-Champaign (Champaign, IL) |
| 2011 | 19 | | 575 | FrRnd | 4 | Orioles | Dustin Ward (minors) | | | | | | | | | | | | | 4Yr | University of Central Arkansas (Conway, AR) |
| 2011 | 19 | | 578 | FrRnd | 7 | Indians | Shawn Morimando (minors) | | | | | | | | | | | | | HS | Ocean Lakes HS (Virginia Beach, VA) |
| 2011 | 19 | | 580 | FrRnd | 9 | Astros | Mitchell Lambson (minors) | | | | | | | | | | | | | 4Yr | Arizona State University (Tempe, AZ) |
| 2011 | 19 | | 585 | FrRnd | 14 | Angels | Ryan Crowley (minors) | | | | | | | | | | | | | JC | Northwest Florida State College (Niceville, FL) |
| 2011 | 19 | | 586 | FrRnd | 15 | Athletics | Eric Potter (minors) | | | | | | | | | | | | | 4Yr | University of Maryland (College Park, MD) |
| 2011 | 19 | | 590 | FrRnd | 19 | Cardinals | Nicholas Gillung (minors) | | | | | | | | | | | | | 4Yr | Mercyhurst College (Erie, PA) |
| 2011 | 19 | | 593 | FrRnd | 22 | Padres | Jeremy Gigliotti (minors) | | | | | | | | | | | | | 4Yr | East Stroudsburg University of Pennsylvania (East Stroudsburg, PA) |
| 2011 | 19 | | 595 | FrRnd | 24 | Reds | Chris Joyce (minors) | | | | | | | | | | | | | JC | Santa Barbara City College (Santa Barbara, CA) |
| 2011 | 20 | | 608 | FrRnd | 7 | Indians | Dillon Peters (minors) | | | | | | | | | | | | | HS | Cathedral HS (Indianapolis, IN) |
| 2011 | 20 | | 615 | FrRnd | 14 | Angels | Juan Carlin (minors) | | | | | | | | | | | | | 4Yr | University of South Florida (Tampa, FL) |
| 2011 | 20 | | 617 | FrRnd | 16 | Tigers | Tyler Barrett (minors) | | | | | | | | | | | | | 4Yr | Lewis-Clark State College (Lewiston, ID) |
| 2011 | 20 | | 622 | FrRnd | 21 | Red Sox | Zachary Good (minors) | | | | | | | | | | | | | JC | Grayson County College (Denison, TX) |
| 2011 | 20 | | 626 | FrRnd | 25 | Braves | Carlos Rodriguez (minors) | | | | | | | | | | | | | HS | Iolani HS (Honolulu, HI) |
| 2011 | 20 | | 627 | FrRnd | 26 | Giants | Mitchell Beacom (minors) | | | | | | | | | | | | | 4Yr | University of California, Los Angeles (Los Angeles, CA) |
| 2011 | 20 | | 629 | FrRnd | 28 | Yankees | Daniel Camarena (minors) | | | | | | | | | | | | | HS | Cathedral Catholic HS (San Diego, CA) |
| 2011 | 21 | | 637 | FrRnd | 6 | Nationals | Todd Simko (minors) | | | | | | | | | | | | | 4Yr | Texas A&M University-Corpus Christi (Corpus Christi, TX) |
| 2011 | 21 | | 639 | FrRnd | 8 | Cubs | Andrew McKirahan (minors) | | | | | | | | | | | | | 4Yr | University of Texas at Austin (Austin, TX) |
| 2011 | 21 | | 644 | FrRnd | 13 | Dodgers | Zakery Qualls (minors) | | | | | | | | | | | | | HS | Rancho HS (Las Vegas, NV) |
| 2011 | 21 | | 647 | FrRnd | 16 | Tigers | Scott Squier (minors) | | | | | | | | | | | | | HS | Greenway HS (Phoenix, AZ) |
| 2011 | 21 | | 650 | FrRnd | 19 | Cardinals | Christopher Kirsch (minors) | | | | | | | | | | | | | JC | Lackawanna CC (Scranton, PA) |
| 2011 | 21 | | 658 | FrRnd | 27 | Twins | Michael Howard (minors) | | | | | | | | | | | | | HS | Prescott HS (Prescott, AZ) |
| 2011 | 22 | | 662 | FrRnd | 1 | Pirates | Mike Jefferson (minors) | | | | | | | | | | | | | 4Yr | Louisiana Tech University (Ruston, LA) |
| 2011 | 22 | | 666 | FrRnd | 5 | Royals | David Middendorf (minors) | | | | | | | | | | | | | 4Yr | Northern Kentucky University (Highland Heights, KY) |
| 2011 | 22 | | 678 | FrRnd | 17 | Rockies | Logan Mahon (minors) | | | | | | | | | | | | | 4Yr | Southeast Missouri State University (Cape Girardeau, MO) |
| 2011 | 22 | | 680 | FrRnd | 19 | Cardinals | Justin Kamplain (minors) | | | | | | | | | | | | | HS | Walker HS (Jasper, AL) |
| 2011 | 22 | | 685 | FrRnd | 24 | Reds | Amir Garrett (minors) | | | | | | | | | | | | | HS | Henderson International School (Henderson, NV) |
| 2011 | 23 | | 707 | FrRnd | 16 | Tigers | Trent Daniel (minors) | | | | | | | | | | | | | 4Yr | University of Arkansas (Fayetteville, AR) |
| 2011 | 23 | | 708 | FrRnd | 17 | Rockies | Brook Hart (minors) | | | | | | | | | | | | | 4Yr | Yale University (New Haven, CT) |
| 2011 | 23 | | 712 | FrRnd | 21 | Red Sox | Jarrett Brown (minors) | | | | | | | | | | | | | HS | Salem HS (Conyers, GA) |
| 2011 | 23 | | 713 | FrRnd | 22 | Padres | Robert Eisenbach (minors) | | | | | | | | | | | | | 4Yr | Faulkner University (Montgomery, AL) |
| 2011 | 23 | | 714 | FrRnd | 23 | Rangers | Michael Mason (minors) | | | | | | | | | | | | | 4Yr | Marshall University (Huntington, WV) |
| 2011 | 24 | | 727 | FrRnd | 6 | Nationals | Kyle Ottoson (minors) | | | | | | | | | | | | | 4Yr | Arizona State University (Tempe, AZ) |
| 2011 | 24 | | 737 | FrRnd | 16 | Tigers | Matt Crouse (minors) | | | | | | | | | | | | | 4Yr | University of Mississippi (Oxford, MS) |
| 2011 | 24 | | 739 | FrRnd | 18 | Blue Jays | David Rollins (minors) | | | | | | | | | | | | | JC | San Jacinto College North (Houston, TX) |
| 2011 | 24 | | 740 | FrRnd | 19 | Cardinals | Jonathan Cornelius (minors) | | | | | | | | | | | | | 4Yr | Florida Institute of Technology (Melbourne, FL) |
| 2011 | 24 | | 749 | FrRnd | 28 | Yankees | Matt Tracy (minors) | | | | | | | | | | | | | 4Yr | University of Mississippi (Oxford, MS) |
| 2011 | 25 | | 755 | FrRnd | 4 | Orioles | Michael Finnigan (minors) | | | | | | | | | | | | | JC | San Bernardino Valley College (San Bernardino, CA) |
| 2011 | 25 | | 762 | FrRnd | 11 | Mets | Andrew Reed (minors) | | | | | | | | | | | | | HS | Terre Haute South HS (Terre Haute, IN) |
| 2011 | 25 | | 774 | FrRnd | 23 | Rangers | Jordan Remer (minors) | | | | | | | | | | | | | 4Yr | University of San Francisco (San Francisco, CA) |
| 2011 | 26 | | 786 | FrRnd | 5 | Royals | Joseph Moorefield (minors) | | | | | | | | | | | | | 4Yr | Clemson University (Clemson, SC) |
| 2011 | 26 | | 791 | FrRnd | 10 | Brewers | Josh Smith (minors) | | | | | | | | | | | | | 4Yr | Wichita State University (Wichita, KS) |
| 2011 | 27 | | 817 | FrRnd | 6 | Nationals | Bobby Lucas (minors) | | | | | | | | | | | | | 4Yr | George Washington University (Washington, DC) |
| 2011 | 27 | | 823 | FrRnd | 12 | Marlins | Frankie Reed (minors) | | | | | | | | | | | | | 4Yr | California Polytechnic State University, San Luis Obispo (San Luis Obispo, CA) |
| 2011 | 27 | | 837 | FrRnd | 26 | Giants | Jack Snodgrass (minors) | | | | | | | | | | | | | 4Yr | Austin Peay State University (Clarksville, TN) |
| 2011 | 27 | | 839 | FrRnd | 28 | Yankees | Chaz Hebert (minors) | | | | | | | | | | | | | HS | Breaux Bridge HS (Breaux Bridge, LA) |
| 2011 | 27 | | 841 | FrRnd | 30 | Phillies | Braden Shull (minors) | | | | | | | | | | | | | HS | Mount Pleasant HS (Mount Pleasant, IA) |
| 2011 | 28 | | 842 | FrRnd | 1 | Pirates | Jeffrey Zajac (minors) | | | | | | | | | | | | | HS | Walker Valley HS (Cleveland, TN) |
| 2011 | 28 | | 848 | FrRnd | 7 | Indians | Tyler Nurdin (minors) | | | | | | | | | | | | | JC | Temple College (Temple, TX) |
| 2011 | 28 | | 850 | FrRnd | 9 | Astros | Jordan John (minors) | | | | | | | | | | | | | 4Yr | University of Oklahoma (Norman, OK) |
| 2011 | 28 | | 860 | FrRnd | 19 | Cardinals | Ryan Sherriff (minors) | | | | | | | | | | | | | JC | West Los Angeles College (Culver City, CA) |
| 2011 | 28 | | 866 | FrRnd | 25 | Braves | Matt Talley (minors) | | | | | | | | | | | | | 4Yr | The Citadel (Charleston, SC) |
| 2011 | 28 | | 868 | FrRnd | 27 | Twins | David Hurlbut (minors) | | | | | | | | | | | | | 4Yr | California State University Fullerton (Fullerton, CA) |
| 2011 | 29 | | 888 | FrRnd | 17 | Rockies | Matthew Dermody (minors) | | | | | | | | | | | | | 4Yr | University of Iowa (Iowa City, IA) |
| 2011 | 29 | | 890 | FrRnd | 19 | Cardinals | Christopher Matulis (minors) | | | | | | | | | | | | | 4Yr | University of Central Florida (Orlando, FL) |
| 2011 | 29 | | 898 | FrRnd | 27 | Twins | Derek Thompson (minors) | | | | | | | | | | | | | HS | Teutopolis HS (Teutopolis, IL) |
| 2011 | 30 | | 907 | FrRnd | 6 | Nationals | Bryan Harper (minors) | | | | | | | | | | | | | 4Yr | University of South Carolina (Columbia, SC) |
| 2011 | 30 | | 912 | FrRnd | 11 | Mets | Jacob Hansen (minors) | | | | | | | | | | | | | HS | F. P. Walshe HS (Fort MacLeod, AB) |
| 2011 | 30 | | 921 | FrRnd | 20 | White Sox | Brandon Parrent (minors) | | | | | | | | | | | | | 4Yr | Texas A&M University (College Station, TX) |
| 2011 | 31 | | 933 | FrRnd | 2 | Mariners | Kyle Hunter (minors) | | | | | | | | | | | | | 4Yr | Kansas State University (Manhattan, KS) |
| 2011 | 31 | | 938 | FrRnd | 7 | Indians | Michael Roth (minors) | -0.6 | 9 | 0 | | | | 9 | 1 | 1 | 9.00 | 1.71 | 0 | 4Yr | University of South Carolina (Columbia, SC) |
| 2011 | 31 | | 946 | FrRnd | 15 | Athletics | Nicholas Kuebel (minors) | | | | | | | | | | | | | 4Yr | St. Louis University (St. Louis, MO) |
| 2011 | 31 | | 957 | FrRnd | 26 | Giants | Phil McCormick (minors) | | | | | | | | | | | | | 4Yr | University of Missouri Columbia (Columbia, MO) |
| 2011 | 31 | | 959 | FrRnd | 28 | Yankees | Aaron Bummer (minors) | | | | | | | | | | | | | HS | Sunrise Mountain HS (Peoria, AZ) |
| 2011 | 32 | | 963 | FrRnd | 2 | Mariners | Ryan Hawthorne (minors) | | | | | | | | | | | | | 4Yr | Loyola Marymount University (Los Angeles, CA) |
| 2011 | 32 | | 984 | FrRnd | 23 | Rangers | Sam Robinson (minors) | | | | | | | | | | | | | 4Yr | University of Miami (Coral Gables, FL) |
| 2011 | 32 | | 988 | FrRnd | 27 | Twins | Dylan Chavez (minors) | | | | | | | | | | | | | JC | American River College (Sacramento, CA) |
| 2011 | 33 | | 993 | FrRnd | 2 | Mariners | Jeremy Dobbs (minors) | | | | | | | | | | | | | 4Yr | Austin Peay State University (Clarksville, TN) |
| 2011 | 33 | | 994 | FrRnd | 3 | Diamondbacks | Anthony Banda (minors) | | | | | | | | | | | | | HS | Sinton HS (Sinton, TX) |
| 2011 | 33 | | 996 | FrRnd | 5 | Royals | Abel Gonzales (minors) | | | | | | | | | | | | | 4Yr | Rice University (Houston, TX) |
| 2011 | 33 | | 999 | FrRnd | 8 | Cubs | Sheldon McDonald (minors) | | | | | | | | | | | | | 4Yr | University of British Columbia (Vancouver, BC) |
| 2011 | 33 | | 1001 | FrRnd | 10 | Brewers | Steven Okert (minors) | | | | | | | | | | | | | JC | Grayson County College (Denison, TX) |
| 2011 | 34 | | 1025 | FrRnd | 4 | Orioles | Zach Fowler (minors) | | | | | | | | | | | | | 4Yr | Texas Tech University (Lubbock, TX) |
| 2011 | 34 | | 1036 | FrRnd | 15 | Athletics | Alfredo Unzue (minors) | | | | | | | | | | | | | | |
| 2011 | 34 | | 1042 | FrRnd | 21 | Red Sox | Sean Dartnell (minors) | | | | | | | | | | | | | HS | Vauxhall HS (Vauxhall, AB) |
| 2011 | 35 | | 1064 | FrRnd | 13 | Dodgers | Michael Thomas (minors) | | | | | | | | | | | | | 4Yr | Rider University (Lawrenceville, NJ) |
| 2011 | 35 | | 1065 | FrRnd | 14 | Angels | Stephen Tromblee (minors) | | | | | | | | | | | | | 4Yr | Lamar University (Beaumont, TX) |
| 2011 | 35 | | 1076 | FrRnd | 25 | Braves | Michael Hashem (minors) | | | | | | | | | | | | | 4Yr | Fisher College (Boston, MA) |
| 2011 | 35 | | 1081 | FrRnd | 30 | Phillies | Kyle Freeland (minors) | | | | | | | | | | | | | HS | Thomas Jefferson HS (Denver, CO) |
| 2011 | 36 | | 1087 | FrRnd | 6 | Nationals | Ben Hawkins (minors) | | | | | | | | | | | | | 4Yr | University of West Florida (Pensacola, FL) |
| 2011 | 36 | | 1088 | FrRnd | 7 | Indians | Abelisario Guerrero (minors) | | | | | | | | | | | | | JC | Galveston College (Galveston, TX) |
| 2011 | 37 | | 1114 | FrRnd | 3 | Diamondbacks | Elroy Urbina (minors) | | | | | | | | | | | | | 4Yr | University of the Incarnate Word (San Antonio, TX) |
| 2011 | 37 | | 1128 | FrRnd | 17 | Rockies | Brandon Bonilla (minors) | | | | | | | | | | | | | HS | The Pendleton School (Bradenton, FL) |
| 2011 | 37 | | 1131 | FrRnd | 20 | White Sox | Todd Kibby (minors) | | | | | | | | | | | | | JC | St. Petersburg College (St. Petersburg, FL) |
| 2011 | 38 | | 1147 | FrRnd | 6 | Nationals | Brett Mooneyham (minors) | | | | | | | | | | | | | 4Yr | Stanford University (Palo Alto, CA) |
| 2011 | 38 | | 1171 | FrRnd | 30 | Phillies | Brett Maggard (minors) | | | | | | | | | | | | | HS | Hernando HS (Hernando, FL) |
| 2011 | 39 | | 1181 | FrRnd | 10 | Brewers | Elliot Glynn (minors) | | | | | | | | | | | | | 4Yr | University of Connecticut (Storrs, CT) |
| 2011 | 39 | | 1190 | FrRnd | 19 | Cardinals | Tyler Melling (minors) | | | | | | | | | | | | | 4Yr | Miami University of Ohio (Oxford, OH) |
| 2011 | 39 | | 1191 | FrRnd | 20 | White Sox | Javier Reynoso (minors) | | | | | | | | | | | | | HS | Brooks-DeBartolo Collegiate HS (Tampa, FL) |
| 2011 | 39 | | 1197 | FrRnd | 26 | Giants | Ryan Holland (minors) | | | | | | | | | | | | | 4Yr | University of Memphis (Memphis, TN) |
| 2011 | 39 | | 1199 | FrRnd | 28 | Yankees | Taylor Guilbeau (minors) | | | | | | | | | | | | | HS | Zachary HS (Zachary, LA) |
| 2011 | 39 | | 1200 | FrRnd | 29 | Rays | Theron Geith (minors) | | | | | | | | | | | | | 4Yr | University of Louisiana at Lafayette (Lafayette, LA) |
| 2011 | 40 | | 1205 | FrRnd | 4 | Orioles | Bennett Parry (minors) | | | | | | | | | | | | | | |
| 2011 | 40 | | 1222 | FrRnd | 21 | Red Sox | Jordan Gross (minors) | | | | | | | | | | | | | HS | Don Bosco Preparatory HS (Ramsey, NJ) |
| 2011 | 41 | | 1242 | FrRnd | 11 | Mets | Mark Picca (minors) | | | | | | | | | | | | | 4Yr | University of Texas at Arlington (Arlington, TX) |
| 2011 | 41 | | 1257 | FrRnd | 26 | Giants | Steven Neff (minors) | | | | | | | | | | | | | 4Yr | University of South Carolina (Columbia, SC) |
| 2011 | 41 | | 1260 | FrRnd | 29 | Rays | Shay Crawford (minors) | | | | | | | | | | | | | 4Yr | Lee University (Cleveland, TN) |
| 2011 | 42 | | 1273 | FrRnd | 12 | Marlins | Jerad Grundy (minors) | | | | | | | | | | | | | JC | Heartland CC (Normal, IL) |
| 2011 | 42 | | 1279 | FrRnd | 18 | Blue Jays | Shane Davis (minors) | | | | | | | | | | | | | 4Yr | Canisius College (Buffalo, NY) |
| 2011 | 42 | | 1288 | FrRnd | 27 | Twins | Matt Tomshaw (minors) | | | | | | | | | | | | | 4Yr | Jacksonville University (Jacksonville, FL) |
| 2011 | 42 | | 1291 | FrRnd | 30 | Phillies | Andre Kinder (minors) | | | | | | | | | | | | | 4Yr | Peru State College (Peru, NE) |
| 2011 | 43 | | 1298 | FrRnd | 7 | Indians | Geoffrey Davenport (minors) | | | | | | | | | | | | | 4Yr | University of Arkansas (Fayetteville, AR) |
| 2011 | 43 | | 1303 | FrRnd | 12 | Marlins | Andrew Leenhouts (minors) | | | | | | | | | | | | | 4Yr | Northeastern University (Boston, MA) |
| 2011 | 43 | | 1306 | FrRnd | 15 | Athletics | Adam Frank (minors) | | | | | | | | | | | | | HS | Williams Field HS (Gilbert, AZ) |
| 2011 | 43 | | 1309 | FrRnd | 18 | Blue Jays | Jake Eliopoulos (minors) | | | | | | | | | | | | | | |
| 2011 | 44 | | 1325 | FrRnd | 4 | Orioles | Patrick Merkling (minors) | | | | | | | | | | | | | JC | Chattanooga State Technical Community College (Chattanooga, TN) |
| 2011 | 44 | | 1326 | FrRnd | 5 | Royals | Andrew Vasquez (minors) | | | | | | | | | | | | | HS | Los Osos HS (Rancho Cucamonga, CA) |
| 2011 | 44 | | 1341 | FrRnd | 20 | White Sox | Joseph Pistorese (minors) | | | | | | | | | | | | | HS | Flathead HS (Kalispell, MT) |
| 2011 | 44 | | 1343 | FrRnd | 22 | Padres | Spenser Linney (minors) | | | | | | | | | | | | | HS | Head-Royce HS (Oakland, CA) |
| 2011 | 44 | | 1344 | FrRnd | 23 | Rangers | Philip Pfeifer (minors) | | | | | | | | | | | | | HS | Farragut HS (Knoxville, TN) |
| 2011 | 44 | | 1351 | FrRnd | 30 | Phillies | Nevin Wilson (minors) | | | | | | | | | | | | | HS | Chaparral HS (Scottsdale, AZ) |
| 2011 | 45 | | 1352 | FrRnd | 1 | Pirates | Robert Ingram (minors) | | | | | | | | | | | | | JC | Yavapai College (Prescott, AZ) |
| 2011 | 45 | | 1374 | FrRnd | 23 | Rangers | Brandon Finnegan (minors) | | | | | | | | | | | | | HS | Southwest HS (Fort Worth, TX) |
| 2011 | 45 | | 1375 | FrRnd | 24 | Reds | Travis Radke (minors) | | | | | | | | | | | | | HS | Oaks Christian HS (Westlake, CA) |
| 2011 | 45 | | 1377 | FrRnd | 26 | Giants | Brian Maloney (minors) | | | | | | | | | | | | | 4Yr | Franklin Pierce University (Rindge, NH) |
| 2011 | 46 | | 1385 | FrRnd | 4 | Orioles | Mark Reyes (minors) | | | | | | | | | | | | | HS | Jessieville HS (Jessieville, AR) |
| 2011 | 46 | | 1395 | FrRnd | 14 | Angels | Michael Johnson (minors) | | | | | | | | | | | | | JC | Hillsborough Community College (Tampa, FL) |
| 2011 | 46 | | 1406 | FrRnd | 25 | Braves | John Means (minors) | | | | | | | | | | | | | HS | Gardner-Edgerton HS (Gardner, KS) |
| 2011 | 46 | | 1408 | FrRnd | 27 | Twins | Jared Dettmann (minors) | | | | | | | | | | | | | HS | Somerset HS (Somerset, WI) |
| 2011 | 47 | | 1417 | FrRnd | 6 | Nationals | Timothy Montgomery (minors) | | | | | | | | | | | | | HS | Rockmart HS (Rockmart, GA) |
| 2011 | 47 | | 1420 | FrRnd | 9 | Astros | Zachary Hardoin (minors) | | | | | | | | | | | | | 4Yr | University of Missouri Columbia (Columbia, MO) |
| 2011 | 47 | | 1424 | FrRnd | 13 | Dodgers | Gregg Downing (minors) | | | | | | | | | | | | | 4Yr | Franklin Pierce University (Rindge, NH) |
| 2011 | 47 | | 1436 | FrRnd | 25 | Braves | Dane Gronewald (minors) | | | | | | | | | | | | | JC | Jefferson College (Hillsboro, MO) |
| 2011 | 47 | | 1438 | FrRnd | 27 | Twins | John Hochstatter (minors) | | | | | | | | | | | | | HS | San Ramon Valley HS (Danville, CA) |
| 2011 | 48 | | 1449 | FrRnd | 8 | Cubs | Sam Howard (minors) | | | | | | | | | | | | | HS | Cartersville HS (Cartersville, GA) |
| 2011 | 48 | | 1451 | FrRnd | 10 | Brewers | Michael Francisco (minors) | | | | | | | | | | | | | 4Yr | Villanova University (Villanova, PA) |
| 2011 | 48 | | 1465 | FrRnd | 24 | Reds | Jon Webb (minors) | | | | | | | | | | | | | 4Yr | University of South Carolina (Columbia, SC) |
| 2011 | 48 | | 1469 | FrRnd | 28 | Yankees | Wesley Benjamin (minors) | | | | | | | | | | | | | HS | St. Charles East HS (St. Charles, IL) |
| 2011 | 48 | | 1470 | FrRnd | 29 | Rays | Brandon Leibrandt (minors) | | | | | | | | | | | | | HS | Marist School (Atlanta, GA) |
| 2011 | 49 | | 1479 | FrRnd | 8 | Cubs | Antonio Gonzales (minors) | | | | | | | | | | | | | HS | Damien HS (La Verne, CA) |
| 2011 | 49 | | 1482 | FrRnd | 11 | Mets | Sean Buckle (minors) | | | | | | | | | | | | | HS | Woodrow Wilson HS (Long Beach, CA) |
| 2011 | 49 | | 1489 | FrRnd | 18 | Blue Jays | Charles LaMar (minors) | | | | | | | | | | | | | HS | Clearwater Central Catholic HS (Clearwater, FL) |
| 2011 | 50 | | 1513 | FrRnd | 12 | Marlins | Cory Caruso (minors) | | | | | | | | | | | | | 4Yr | California State University San Bernardino (San Bernardino, CA) |