| 1988 | 1 | | 3 | FrRnd | 3 | Braves | Steve Avery (minors) | 14.0 | 306 | 437 | 4 | .174 | .446 | 297 | 96 | 83 | 4.19 | 1.35 | 0 | HS | Kennedy HS (Taylor, MI) |
| 1988 | 1 | | 8 | FrRnd | 8 | Angels | Jim Abbott (minors) | 19.9 | 263 | 21 | 0 | .095 | .190 | 263 | 87 | 108 | 4.25 | 1.43 | 0 | 4Yr | University of Michigan (Ann Arbor, MI) |
| 1988 | 1 | | 11 | FrRnd | 11 | Phillies | Pat Combs (minors) | 1.8 | 56 | 95 | 0 | .147 | .395 | 56 | 17 | 17 | 4.22 | 1.46 | 0 | 4Yr | Baylor University (Waco, TX) |
| 1988 | 1 | | 12 | FrRnd | 12 | Red Sox | Tom Fischer (minors) | | | | | | | | | | | | | 4Yr | University of Wisconsin at Madison (Madison, WI) |
| 1988 | 1s | | 27 | FrRnd | 27 | Indians | *Jeff Mutis (minors) | -1.9 | 58 | 3 | 0 | .000 | .000 | 58 | 4 | 11 | 6.48 | 1.76 | 0 | 4Yr | Lafayette College (Easton, PA) |
| 1988 | 2 | | 34 | FrRnd | 4 | Orioles | Arthur Rhodes (minors) | 15.4 | 902 | 6 | 0 | .167 | .333 | 900 | 87 | 70 | 4.08 | 1.30 | 33 | HS | La Vega HS (Waco, TX) |
| 1988 | 2 | | 47 | FrRnd | 17 | Giants | Chris Hancock (minors) | | | | | | | | | | | | | HS | Fontana HS (Fontana, CA) |
| 1988 | 2 | | 49 | FrRnd | 19 | Expos | Chris Nabholz (minors) | 5.6 | 141 | 178 | 0 | .107 | .259 | 141 | 37 | 35 | 3.94 | 1.34 | 0 | 4Yr | Towson University (Towson, MD) |
| 1988 | 2 | | 50 | FrRnd | 20 | Twins | Alan Newman (minors) | -0.2 | 19 | 0 | 0 | | | 19 | 2 | 2 | 7.94 | 2.24 | 0 | JC | Fullerton College (Fullerton, CA) |
| 1988 | 3 | | 63 | FrRnd | 6 | Rangers | Darren Oliver (minors) | 22.4 | 742 | 217 | 1 | .221 | .544 | 733 | 117 | 95 | 4.52 | 1.44 | 7 | HS | Rio Linda HS (Rio Linda, CA) |
| 1988 | 4 | | 91 | FrRnd | 8 | Angels | J.R. Phillips (minors) | -1.5 | 242 | 501 | 23 | .188 | .614 | | | | | | | HS | Bishop Amat Memorial HS (La Puente, CA) |
| 1988 | 4 | | 97 | FrRnd | 14 | Mariners | Lee Hancock (minors) | -0.2 | 24 | 0 | 0 | | | 24 | 0 | 0 | 4.45 | 1.33 | 0 | 4Yr | California Polytechnic State University, San Luis Obispo (San Luis Obispo, CA) |
| 1988 | 4 | | 105 | FrRnd | 22 | Yankees | Todd Malone (minors) | | | | | | | | | | | | | HS | Casa Roble HS (Orangevale, CA) |
| 1988 | 5 | | 117 | FrRnd | 8 | Angels | David Neal (minors) | | | | | | | | | | | | | HS | Montgomery HS (Wilmer, AL) |
| 1988 | 5 | | 119 | FrRnd | 10 | White Sox | Joey Eischen (minors) | 3.6 | 327 | 28 | 0 | .179 | .421 | 324 | 11 | 9 | 3.67 | 1.47 | 3 | HS | West Covina HS (West Covina, CA) |
| 1988 | 6 | | 139 | FrRnd | 4 | Orioles | Tom Martin (minors) | 0.4 | 376 | 12 | 0 | .000 | .000 | 376 | 11 | 9 | 4.92 | 1.52 | 3 | HS | Bay HS (Panama City, FL) |
| 1988 | 6 | | 147 | FrRnd | 12 | Red Sox | Ed Riley (minors) | | | | | | | | | | | | | HS | St. Peter's HS (Worcester, MA) |
| 1988 | 6 | | 157 | FrRnd | 22 | Yankees | Jeff Johnson (minors) | -2.5 | 38 | 0 | 0 | | | 38 | 8 | 16 | 6.52 | 1.63 | 0 | 4Yr | University of North Carolina at Charlotte (Charlotte, NC) |
| 1988 | 6 | | 158 | FrRnd | 23 | Cardinals | Rheal Cormier (minors) | 9.7 | 684 | 192 | 0 | .188 | .431 | 683 | 71 | 64 | 4.03 | 1.28 | 2 | JC | Community College of Rhode Island (Warwick, RI) |
| 1988 | 7 | | 172 | FrRnd | 11 | Phillies | Michael Owens (minors) | | | | | | | | | | | | | 4Yr | University of Massachusetts Amherst (Amherst, MA) |
| 1988 | 7 | | 173 | FrRnd | 12 | Red Sox | David Owen (minors) | | | | | | | | | | | | | 4Yr | Carson-Newman College (Jefferson City, TN) |
| 1988 | 7 | | 187 | FrRnd | 26 | Tigers | Tim Brader (minors) | | | | | | | | | | | | | JC | Shelton State Community College (Tuscaloosa, AL) |
| 1988 | 8 | | 189 | FrRnd | 2 | Indians | Olonzo Woodfin (minors) | | | | | | | | | | | | | HS | Sylmar HS (Sylmar, CA) |
| 1988 | 9 | | 217 | FrRnd | 4 | Orioles | Mike Linskey (minors) | | | | | | | | | | | | | 4Yr | James Madison University (Harrisonburg, VA) |
| 1988 | 9 | | 218 | FrRnd | 5 | Dodgers | Jim Poole (minors) | 1.1 | 431 | 8 | 0 | .125 | .375 | 431 | 22 | 12 | 4.31 | 1.47 | 4 | 4Yr | Georgia Institute of Technology (Atlanta, GA) |
| 1988 | 9 | | 222 | FrRnd | 9 | Cubs | Dennis Gray (minors) | | | | | | | | | | | | | HS | Banning HS (Banning, CA) |
| 1988 | 9 | | 226 | FrRnd | 13 | Pirates | Jeff Payne (minors) | | | | | | | | | | | | | HS | University HS (Morgantown, WV) |
| 1988 | 9 | | 230 | FrRnd | 17 | Giants | Kevin Rogers (minors) | 1.1 | 79 | 12 | 0 | .167 | .333 | 79 | 2 | 4 | 3.17 | 1.32 | 0 | JC | Mississippi Delta Community College (Moorhead, MS) |
| 1988 | 9 | | 233 | FrRnd | 20 | Twins | Doug Simons (minors) | -1.5 | 49 | 3 | 0 | .000 | .000 | 49 | 2 | 3 | 6.68 | 1.38 | 1 | 4Yr | Pepperdine University (Malibu, CA) |
| 1988 | 9 | | 234 | FrRnd | 21 | Mets | Patrick Leinen (minors) | | | | | | | | | | | | | 4Yr | University of Nebraska at Lincoln (Lincoln, NE) |
| 1988 | 10 | | 245 | FrRnd | 6 | Rangers | Eric McCray (minors) | | | | | | | | | | | | | HS | Farmerville HS (Farmerville, LA) |
| 1988 | 10 | | 246 | FrRnd | 7 | Astros | David Klinefelter (minors) | | | | | | | | | | | | | JC | Allegheny College (Meadville, PA) |
| 1988 | 10 | | 259 | FrRnd | 20 | Twins | Jody Harrington (minors) | | | | | | | | | | | | | HS | Armijo HS (Fairfield, CA) |
| 1988 | 10 | | 260 | FrRnd | 21 | Mets | Andrew Fidler (minors) | | | | | | | | | | | | | HS | Mothacton HS (Norristown, PA) |
| 1988 | 10 | | 264 | FrRnd | 25 | Blue Jays | Anthony Ward (minors) | | | | | | | | | | | | | 4Yr | Oral Roberts University (Tulsa, OK) |
| 1988 | 11 | | 283 | FrRnd | 18 | Royals | Mike Magnante (minors) | 5.8 | 484 | 6 | 0 | .333 | .667 | 484 | 26 | 32 | 4.08 | 1.46 | 3 | 4Yr | University of California, Los Angeles (Los Angeles, CA) |
| 1988 | 11 | | 286 | FrRnd | 21 | Mets | Gregg Langbehn (minors) | | | | | | | | | | | | | HS | Everest HS (Schofield, WI) |
| 1988 | 11 | | 289 | FrRnd | 24 | Brewers | Daniel Kapea (minors) | | | | | | | | | | | | | 4Yr | University of Hawaii at Manoa (Honolulu, HI) |
| 1988 | 12 | | 297 | FrRnd | 6 | Rangers | Cedric Shaw (minors) | | | | | | | | | | | | | 4Yr | Grambling State University (Grambling, LA) |
| 1988 | 12 | | 305 | FrRnd | 14 | Mariners | Nick Felix (minors) | | | | | | | | | | | | | 4Yr | Texas A&M University (College Station, TX) |
| 1988 | 13 | | 337 | FrRnd | 20 | Twins | Michael Pomeranz (minors) | | | | | | | | | | | | | 4Yr | Clemson University (Clemson, SC) |
| 1988 | 14 | | 348 | FrRnd | 5 | Dodgers | Dana Allison (minors) | -0.3 | 11 | 0 | 0 | | | 11 | 1 | 1 | 7.36 | 1.91 | 0 | 4Yr | James Madison University (Harrisonburg, VA) |
| 1988 | 14 | | 363 | FrRnd | 20 | Twins | Steven Muh (minors) | | | | | | | | | | | | | 4Yr | University of Georgia (Athens, GA) |
| 1988 | 14 | | 366 | FrRnd | 23 | Cardinals | John Cebuhar (minors) | | | | | | | | | | | | | 4Yr | University of Arkansas (Fayetteville, AR) |
| 1988 | 15 | | 371 | FrRnd | 2 | Indians | Charles Alexander (minors) | | | | | | | | | | | | | 4Yr | Western Michigan University (Kalamazoo, MI) |
| 1988 | 15 | | 376 | FrRnd | 7 | Astros | Wally Trice (minors) | | | | | | | | | | | | | 4Yr | U.S. International University (San Diego, CA) |
| 1988 | 15 | | 379 | FrRnd | 10 | White Sox | Fred Dabney (minors) | | | | | | | | | | | | | JC | Seminole Community College (Sanford, FL) |
| 1988 | 15 | | 381 | FrRnd | 12 | Red Sox | Howard Landry (minors) | | | | | | | | | | | | | 4Yr | University of Louisiana at Lafayette (Lafayette, LA) |
| 1988 | 15 | | 384 | FrRnd | 15 | Reds | Craig Rapp (minors) | | | | | | | | | | | | | HS | Red Land HS (Lewisberry, PA) |
| 1988 | 16 | | 399 | FrRnd | 4 | Orioles | Robert Bretwisch (minors) | | | | | | | | | | | | | 4Yr | Bradley University (Peoria, IL) |
| 1988 | 16 | | 401 | FrRnd | 6 | Rangers | John Sipple (minors) | | | | | | | | | | | | | 4Yr | Oregon State University (Corvallis, OR) |
| 1988 | 16 | | 410 | FrRnd | 15 | Reds | Scott McCarty (minors) | | | | | | | | | | | | | JC | San Jacinto College (Pasadena, TX) |
| 1988 | 16 | | 411 | FrRnd | 16 | Athletics | Michael Butler (minors) | | | | | | | | | | | | | HS | North Caroline HS (Denton, MD) |
| 1988 | 17 | | 432 | FrRnd | 11 | Phillies | Brian Walker (minors) | | | | | | | | | | | | | HS | Capistrano Valley HS (Mission Viejo, CA) |
| 1988 | 17 | | 434 | FrRnd | 13 | Pirates | Bobby Underwood (minors) | | | | | | | | | | | | | 4Yr | University of South Carolina (Columbia, SC) |
| 1988 | 17 | | 435 | FrRnd | 14 | Mariners | Jim Kosnik (minors) | | | | | | | | | | | | | JC | Oakland Community College (Farmington Hills, MI) |
| 1988 | 17 | | 444 | FrRnd | 23 | Cardinals | Dave Richardson (minors) | | | | | | | | | | | | | 4Yr | Middle Tennessee State University (Murfreesboro, TN) |
| 1988 | 18 | | 448 | FrRnd | 1 | Padres | Joe Murdock (minors) | | | | | | | | | | | | | 4Yr | Southern Arkansas University (Magnolia, AR) |
| 1988 | 18 | | 449 | FrRnd | 2 | Indians | Darrin Paxton (minors) | | | | | | | | | | | | | HS | East HS (Wichita, KS) |
| 1988 | 18 | | 454 | FrRnd | 7 | Astros | Rodney Windes (minors) | | | | | | | | | | | | | 4Yr | California State University Los Angeles (Los Angeles, CA) |
| 1988 | 18 | | 459 | FrRnd | 12 | Red Sox | Hilly Hathaway (minors) | 0.5 | 13 | 0 | 0 | | | 13 | 4 | 3 | 5.29 | 1.71 | 0 | HS | Sandalwood HS (Jacksonville, FL) |
| 1988 | 18 | | 460 | FrRnd | 13 | Pirates | Randy Tomlin (minors) | 6.4 | 107 | 181 | 0 | .160 | .363 | 106 | 30 | 31 | 3.43 | 1.25 | 0 | 4Yr | Liberty University (Lynchburg, VA) |
| 1988 | 18 | | 466 | FrRnd | 19 | Expos | Darrin Winston (minors) | -0.4 | 34 | 3 | 0 | .333 | .833 | 34 | 4 | 2 | 5.84 | 1.30 | 1 | 4Yr | Rutgers, the State University of New Jersey (New Brunswick, NJ) |
| 1988 | 18 | | 469 | FrRnd | 22 | Yankees | Jerry Nielsen (minors) | -0.2 | 30 | 0 | 0 | | | 30 | 1 | 0 | 5.91 | 1.78 | 0 | 4Yr | Florida State University (Tallahassee, FL) |
| 1988 | 19 | | 474 | FrRnd | 1 | Padres | Greg Ebbert (minors) | | | | | | | | | | | | | HS | Lake Brantley HS (Altamonte Springs, FL) |
| 1988 | 19 | | 478 | FrRnd | 5 | Dodgers | James Wray (minors) | | | | | | | | | | | | | 4Yr | Troy University (Troy, AL) |
| 1988 | 19 | | 495 | FrRnd | 22 | Yankees | Stevie Perry (minors) | | | | | | | | | | | | | HS | King HS (Detroit, MI) |
| 1988 | 19 | | 498 | FrRnd | 25 | Blue Jays | Tim Bruzdewicz (minors) | | | | | | | | | | | | | JC | Allegheny College (Meadville, PA) |
| 1988 | 20 | | 503 | FrRnd | 4 | Orioles | Robert Doman (minors) | | | | | | | | | | | | | 4Yr | James Madison University (Harrisonburg, VA) |
| 1988 | 20 | | 513 | FrRnd | 14 | Mariners | Tom Liss (minors) | | | | | | | | | | | | | 4Yr | University of Detroit Mercy (Detroit, MI) |
| 1988 | 20 | | 516 | FrRnd | 17 | Giants | Eddy Durham (minors) | | | | | | | | | | | | | 4Yr | Wichita State University (Wichita, KS) |
| 1988 | 20 | | 518 | FrRnd | 19 | Expos | Brian Sajonia (minors) | | | | | | | | | | | | | 4Yr | Washington State University (Pullman, WA) |
| 1988 | 20 | | 520 | FrRnd | 21 | Mets | Jon Hudson (minors) | | | | | | | | | | | | | 4Yr | University of Kentucky (Lexington, KY) |
| 1988 | 20 | | 522 | FrRnd | 23 | Cardinals | Stephen Callahan (minors) | | | | | | | | | | | | | 4Yr | Lewis-Clark State College (Lewiston, ID) |
| 1988 | 21 | | 549 | FrRnd | 24 | Brewers | Brian Dodd (minors) | | | | | | | | | | | | | 4Yr | Arizona State University (Tempe, AZ) |
| 1988 | 22 | | 556 | FrRnd | 5 | Dodgers | Michael St. Estaben (minors) | | | | | | | | | | | | | HS | Chino HS (Chino, CA) |
| 1988 | 22 | | 561 | FrRnd | 10 | White Sox | Michael Galvan (minors) | | | | | | | | | | | | | 4Yr | Louisiana Tech University (Ruston, LA) |
| 1988 | 22 | | 567 | FrRnd | 16 | Athletics | Ray Harris (minors) | | | | | | | | | | | | | 4Yr | University of Arkansas (Fayetteville, AR) |
| 1988 | 22 | | 570 | FrRnd | 19 | Expos | Brian Pease (minors) | | | | | | | | | | | | | HS | Bonny Eagle HS (Cornish, ME) |
| 1988 | 22 | | 577 | FrRnd | 26 | Tigers | William Warrecker (minors) | | | | | | | | | | | | | 4Yr | University of California, Berkeley (Berkeley, CA) |
| 1988 | 23 | | 583 | FrRnd | 6 | Rangers | Mike Reitzel (minors) | | | | | | | | | | | | | 4Yr | Northeastern State University (Tahlequah, OK) |
| 1988 | 23 | | 584 | FrRnd | 7 | Astros | James Desapio (minors) | | | | | | | | | | | | | 4Yr | St. Francis University (Brooklyn, NY) |
| 1988 | 23 | | 592 | FrRnd | 15 | Reds | Chris Keim (minors) | | | | | | | | | | | | | JC | Taft College (Taft, CA) |
| 1988 | 24 | | 604 | FrRnd | 1 | Padres | Brad Royer (minors) | | | | | | | | | | | | | 4Yr | California Polytechnic State University, Pomona (Pomona, CA) |
| 1988 | 24 | | 626 | FrRnd | 23 | Cardinals | John Lepley (minors) | | | | | | | | | | | | | 4Yr | University of Nebraska at Lincoln (Lincoln, NE) |
| 1988 | 25 | | 630 | FrRnd | 1 | Padres | Renay Bryand (minors) | | | | | | | | | | | | | 4Yr | University of California, Santa Barbara (Santa Barbara, CA) |
| 1988 | 25 | | 633 | FrRnd | 4 | Orioles | Brian Barnes (minors) | 3.3 | 116 | 107 | 0 | .140 | .354 | 116 | 14 | 22 | 3.94 | 1.40 | 3 | 4Yr | Clemson University (Clemson, SC) |
| 1988 | 25 | | 653 | FrRnd | 24 | Brewers | Kevin Carmody (minors) | | | | | | | | | | | | | 4Yr | North Adams State College (North Adams, MA) |
| 1988 | 26 | | 658 | FrRnd | 3 | Braves | Craig Bradshaw (minors) | | | | | | | | | | | | | HS | Alexandria HS (Alexandria, LA) |
| 1988 | 26 | | 666 | FrRnd | 11 | Phillies | Jamie Allen (minors) | | | | | | | | | | | | | JC | Hillsborough Community College (Tampa, FL) |
| 1988 | 26 | | 671 | FrRnd | 16 | Athletics | Tony Ariola (minors) | | | | | | | | | | | | | 4Yr | Northwestern University (Evanston, IL) |
| 1988 | 26 | | 675 | FrRnd | 20 | Twins | Steve Gill (minors) | | | | | | | | | | | | | JC | Cypress College (Cypress, CA) |
| 1988 | 26 | | 676 | FrRnd | 21 | Mets | Sean Lawrence (minors) | -0.4 | 7 | 6 | 0 | .000 | .000 | 7 | 2 | 1 | 7.32 | 1.78 | 0 | HS | River Forest HS (Oak Park, IL) |
| 1988 | 27 | | 689 | FrRnd | 8 | Angels | Bruce Vegely (minors) | | | | | | | | | | | | | 4Yr | California State University Dominguez Hills (Carson, CA) |
| 1988 | 27 | | 693 | FrRnd | 12 | Red Sox | Mark Mitchelson (minors) | | | | | | | | | | | | | JC | Hillsborough Community College (Tampa, FL) |
| 1988 | 27 | | 698 | FrRnd | 17 | Giants | David Wuthrich (minors) | | | | | | | | | | | | | 4Yr | Troy University (Troy, AL) |
| 1988 | 27 | | 705 | FrRnd | 24 | Brewers | David Fitzgerald (minors) | | | | | | | | | | | | | 4Yr | Davidson College (Davidson, NC) |
| 1988 | 28 | | 716 | FrRnd | 9 | Cubs | Timothy Ellis (minors) | | | | | | | | | | | | | JC | Rosemont JC (Sacramento, CA) |
| 1988 | 28 | | 719 | FrRnd | 12 | Red Sox | Scott Taylor (minors) | -0.2 | 20 | 0 | 0 | | | 20 | 1 | 2 | 6.31 | 1.68 | 0 | 4Yr | Bowling Green State University (Bowling Green, OH) |
| 1988 | 28 | | 723 | FrRnd | 16 | Athletics | Greg Ferguson (minors) | | | | | | | | | | | | | 4Yr | Virginia Polytechnic Institute and State University (Blacksburg, VA) |
| 1988 | 29 | | 739 | FrRnd | 6 | Rangers | Bobby Gamez (minors) | | | | | | | | | | | | | JC | Chabot College (Hayward, CA) |
| 1988 | 29 | | 740 | FrRnd | 7 | Astros | Anthony Gutierrez (minors) | | | | | | | | | | | | | HS | Englewood HS (Littleton, CO) |
| 1988 | 29 | | 742 | FrRnd | 9 | Cubs | Mike Sodders (minors) | | | | | | | | | | | | | 4Yr | University of Alabama (Tuscaloosa, AL) |
| 1988 | 29 | | 744 | FrRnd | 11 | Phillies | Greg Rehkow (minors) | | | | | | | | | | | | | HS | Blue Springs HS (Blue Springs, MO) |
| 1988 | 29 | | 748 | FrRnd | 15 | Reds | Ted Klamm (minors) | | | | | | | | | | | | | HS | Bishop Ludden HS (Syracuse, NY) |
| 1988 | 30 | | 760 | FrRnd | 1 | Padres | Rob Cantwell (minors) | | | | | | | | | | | | | JC | North Idaho College (Coeur d'Alene, ID) |
| 1988 | 30 | | 770 | FrRnd | 11 | Phillies | Brian Harper (minors) | | | | | | | | | | | | | 4Yr | Southeast Missouri State University (Cape Girardeau, MO) |
| 1988 | 30 | | 772 | FrRnd | 13 | Pirates | Jeff Kuder (minors) | | | | | | | | | | | | | 4Yr | Mount Vernon Nazarene University (Mount Vernon, OH) |
| 1988 | 30 | | 775 | FrRnd | 16 | Athletics | Steve Whitaker (minors) | | | | | | | | | | | | | HS | Atwater HS (Atwater, CA) |
| 1988 | 31 | | 790 | FrRnd | 5 | Dodgers | Clayton Enno (minors) | | | | | | | | | | | | | JC | Des Moines Area Community College (Boone, IA) |
| 1988 | 31 | | 796 | FrRnd | 11 | Phillies | Craig Johnston (minors) | | | | | | | | | | | | | HS | Napa HS (Napa, CA) |
| 1988 | 31 | | 802 | FrRnd | 17 | Giants | William Berry (minors) | | | | | | | | | | | | | JC | Glendale Community College (Glendale, CA) |
| 1988 | 31 | | 803 | FrRnd | 18 | Royals | John McCormick (minors) | | | | | | | | | | | | | 4Yr | The Ohio State University (Columbus, OH) |
| 1988 | 31 | | 805 | FrRnd | 20 | Twins | Chris Hmielewski (minors) | | | | | | | | | | | | | HS | Leyden HS (Franklin Park, IL) |
| 1988 | 32 | | 819 | FrRnd | 8 | Angels | Robert Dodd (minors) | | | | | | | | | | | | | JC | Sacramento City College (Sacramento, CA) |
| 1988 | 32 | | 830 | FrRnd | 19 | Expos | Justin Heinold (minors) | | | | | | | | | | | | | HS | Stroman HS (Victoria, TX) |
| 1988 | 32 | | 833 | FrRnd | 22 | Yankees | John Cummings (minors) | -0.8 | 110 | 3 | 0 | .000 | .000 | 110 | 10 | 15 | 5.33 | 1.65 | 0 | HS | Canyon HS (Anaheim, CA) |
| 1988 | 33 | | 858 | FrRnd | 21 | Mets | Brian Zimmerman (minors) | | | | | | | | | | | | | 4Yr | North Central College (Naperville, IL) |
| 1988 | 33 | | 862 | FrRnd | 25 | Blue Jays | George Tsamis (minors) | -0.6 | 41 | 0 | 0 | | | 41 | 1 | 2 | 6.19 | 1.65 | 1 | 4Yr | Stetson University (DeLand, FL) |
| 1988 | 34 | | 871 | FrRnd | 8 | Angels | Jim Henry (minors) | | | | | | | | | | | | | HS | Placer HS (Auburn, CA) |
| 1988 | 34 | | 873 | FrRnd | 10 | White Sox | Lee Dorsey (minors) | | | | | | | | | | | | | HS | T. L. Hanna HS (Anderson, SC) |
| 1988 | 34 | | 877 | FrRnd | 14 | Mariners | Ben Burnau (minors) | | | | | | | | | | | | | 4Yr | Miami University of Ohio (Oxford, OH) |
| 1988 | 34 | | 888 | FrRnd | 25 | Blue Jays | Jeff Lawrence (minors) | | | | | | | | | | | | | HS | Fallbrook Union HS (Fallbrook, CA) |
| 1988 | 36 | | 930 | FrRnd | 15 | Reds | Mike Malley (minors) | | | | | | | | | | | | | 4Yr | University of Connecticut (Storrs, CT) |
| 1988 | 36 | | 936 | FrRnd | 21 | Mets | Scott Ellrich (minors) | | | | | | | | | | | | | HS | Crystal Lake South HS (Lake In The Hills, IL) |
| 1988 | 37 | | 944 | FrRnd | 3 | Braves | Bill Lange (minors) | | | | | | | | | | | | | JC | Rio Hondo College (Whittier, CA) |
| 1988 | 37 | | 953 | FrRnd | 12 | Red Sox | Steve Worrell (minors) | | | | | | | | | | | | | HS | Lower Cape May Regional HS (Cape May, NJ) |
| 1988 | 38 | | 981 | FrRnd | 14 | Mariners | John Kohli (minors) | | | | | | | | | | | | | 4Yr | University of Nebraska at Lincoln (Lincoln, NE) |
| 1988 | 38 | | 985 | FrRnd | 18 | Royals | Dean McMillin (minors) | | | | | | | | | | | | | HS | Ventura HS (Ventura, CA) |
| 1988 | 38 | | 993 | FrRnd | 26 | Tigers | Bert Patton (minors) | | | | | | | | | | | | | 4Yr | Eastern Michigan University (Ypsilanti, MI) |
| 1988 | 39 | | 1015 | FrRnd | 22 | Cardinals | Scott Buchheit (minors) | | | | | | | | | | | | | HS | St. Dominic HS (O'Fallon, MO) |
| 1988 | 40 | | 1020 | FrRnd | 2 | Indians | Keith Bevenour (minors) | | | | | | | | | | | | | 4Yr | Pennsylvania State University (State College, PA) |
| 1988 | 40 | | 1024 | FrRnd | 6 | Rangers | Kenneth Penland (minors) | | | | | | | | | | | | | 4Yr | University of South Carolina Upstate (Spartanburg, SC) |
| 1988 | 40 | | 1031 | FrRnd | 13 | Mariners | Felix Gurruchaga (minors) | | | | | | | | | | | | | JC | Miami-Dade College (Miami, FL) |
| 1988 | 40 | | 1032 | FrRnd | 14 | Reds | John Edward (minors) | | | | | | | | | | | | | 4Yr | New Mexico State University (Las Cruces, NM) |
| 1988 | 41 | | 1049 | FrRnd | 6 | Rangers | Anthony Peeler (minors) | | | | | | | | | | | | | HS | Paseo HS (Kansas City, MO) |
| 1988 | 41 | | 1055 | FrRnd | 12 | Pirates | Rich Haupt (minors) | | | | | | | | | | | | | HS | Bald Eagle Area HS (Milesburg, PA) |
| 1988 | 41 | | 1062 | FrRnd | 19 | Twins | David Baine (minors) | | | | | | | | | | | | | HS | San Marin HS (Novato, CA) |
| 1988 | 42 | | 1074 | FrRnd | 6 | Rangers | Gregory Kuzma (minors) | | | | | | | | | | | | | 4Yr | Princeton University (Princeton, NJ) |
| 1988 | 42 | | 1080 | FrRnd | 12 | Pirates | Ron Way (minors) | | | | | | | | | | | | | JC | Henry Ford Community College (Dearborn, MI) |
| 1988 | 42 | | 1082 | FrRnd | 14 | Reds | Brian Landy (minors) | | | | | | | | | | | | | 4Yr | Quinnipiac College (Hamden, CT) |
| 1988 | 42 | | 1083 | FrRnd | 15 | Athletics | Cliff Jones (minors) | | | | | | | | | | | | | HS | Oakland HS (Oakland, CA) |
| 1988 | 42 | | 1088 | FrRnd | 20 | Mets | Steve Hinton (minors) | | | | | | | | | | | | | HS | Elgin HS (Elgin, IL) |
| 1988 | 43 | | 1094 | FrRnd | 1 | Padres | Brian Looney (minors) | -0.5 | 7 | 1 | 0 | .000 | .000 | 7 | 0 | 1 | 11.37 | 2.37 | 0 | HS | Gunnery HS (Cheshire, CT) |
| 1988 | 43 | | 1101 | FrRnd | 8 | Angels | Todd Marinovich (minors) | | | | | | | | | | | | | HS | Capistrano Valley HS (Mission Viejo, CA) |
| 1988 | 43 | | 1112 | FrRnd | 19 | Twins | Jeremy Kendall (minors) | | | | | | | | | | | | | HS | Towns County HS (Hiawassee, GA) |
| 1988 | 43 | | 1113 | FrRnd | 20 | Mets | Dan Auchard (minors) | | | | | | | | | | | | | HS | Tracy HS (Tracy, CA) |
| 1988 | 44 | | 1123 | FrRnd | 6 | Rangers | Fred Collins (minors) | | | | | | | | | | | | | JC | Manatee Community College (Bradenton, FL) |
| 1988 | 44 | | 1124 | FrRnd | 7 | Astros | Luis Navarro (minors) | | | | | | | | | | | | | HS | Southwest Miami HS (Miami, FL) |
| 1988 | 44 | | 1129 | FrRnd | 12 | Pirates | Rich Wilson (minors) | | | | | | | | | | | | | 4Yr | Columbus State University (Columbus, GA) |
| 1988 | 44 | | 1135 | FrRnd | 18 | Expos | Jesus Molina (minors) | | | | | | | | | | | | | JC | Pima Community College (Tucson, AZ) |
| 1988 | 44 | | 1137 | FrRnd | 20 | Mets | Brian Buzard (minors) | | | | | | | | | | | | | HS | Neodesha HS (Neodesha, KS) |
| 1988 | 44 | | 1139 | FrRnd | 22 | Cardinals | Derron Spiller (minors) | | | | | | | | | | | | | HS | Rio Mesa HS (Oxnard, CA) |
| 1988 | 46 | | 1182 | FrRnd | 18 | Yankees | Arthur Canestro (minors) | | | | | | | | | | | | | JC | New York City College of Technology (Brooklyn, NY) |
| 1988 | 47 | | 1194 | FrRnd | 9 | Pirates | Craig Juran (minors) | | | | | | | | | | | | | 4Yr | Colorado State University (Fort Collins, CO) |
| 1988 | 47 | | 1197 | FrRnd | 12 | Athletics | Pat Sullivan (minors) | | | | | | | | | | | | | HS | Notre Dame HS (Chattanooga, TN) |
| 1988 | 47 | | 1199 | FrRnd | 14 | Expos | Cord Corbitt (minors) | | | | | | | | | | | | | JC | Palm Beach Community College (Lake Worth, FL) |
| 1988 | 48 | | 1210 | FrRnd | 6 | White Sox | Brian Cordero (minors) | | | | | | | | | | | | | 4Yr | St. John's University (Queens, NY) |
| 1988 | 50 | | 1249 | FrRnd | 11 | Expos | Norm Montoya (minors) | | | | | | | | | | | | | HS | Memorial HS (Newark, CA) |
| 1988 | 53 | | 1288 | FrRnd | 7 | Phillies | Steve Cooke (minors) | 4.3 | 104 | 171 | 0 | .140 | .308 | 104 | 26 | 36 | 4.31 | 1.41 | 1 | HS | Tigard HS (Tigard, OR) |
| 1988 | 53 | | 1290 | FrRnd | 9 | Reds | Dan Schwader (minors) | | | | | | | | | | | | | JC | Kishwaukee College (Malta, IL) |
| 1988 | 54 | | 1300 | FrRnd | 6 | White Sox | Hart Lee Dykes (minors) | | | | | | | | | | | | | 4Yr | Oklahoma State University (Stillwater, OK) |
| 1988 | 56 | | 1321 | FrRnd | 1 | Indians | Michael Bonetto (minors) | | | | | | | | | | | | | HS | Big Bear HS (Big Bear City, CA) |
| 1988 | 56 | | 1327 | FrRnd | 7 | Phillies | Willie Navarette (minors) | | | | | | | | | | | | | JC | Rancho Santiago College (Santa Ana, CA) |
| 1988 | 57 | | 1340 | FrRnd | 7 | Phillies | Dallas Monday (minors) | | | | | | | | | | | | | HS | Jefferson County HS (Dandridge, TN) |
| 1988 | 57 | | 1345 | FrRnd | 12 | Yankees | Mike Eckert (minors) | | | | | | | | | | | | | 4Yr | University of Texas Pan American (Edinburg, TX) |
| 1988 | 60 | | 1379 | FrRnd | 9 | Yankees | Matt Michael (minors) | | | | | | | | | | | | | 4Yr | Morehead State University (Morehead, KY) |
| 1988 | 62 | | 1391 | FrRnd | 3 | Astros | Jim Greenlee (minors) | | | | | | | | | | | | | HS | Pinole Valley HS (Pinole, CA) |
| 1988 | 74 | | 1432 | FrRnd | 1 | Yankees | Oscar Rivas (minors) | | | | | | | | | | | | | JC | San Jacinto College (Pasadena, TX) |