Medicine Hat Blue Jays
- Location: Medicine Hat, AB
- League: Pioneer League 1978-2002
- Affiliation: Toronto Blue Jays 1978-2002
The Medicine Hat Blue Jays were the Toronto Blue Jays affiliate in the Pioneer League beginning in 1978 and remained with their parent club for 25 seasons. Over the years, the club generally struggled on the field and with attendance, but the Jays did have some noteworthy seasons. In 1982, led by skipper Duane Larson and outfielder Kash Beauchamp, they captured their only championship. They reached the championship series again in 1995 under the leadership of manager Darren Balsley but lost the title to the Helena Brewers. The Blue Jays only reached the playoffs one other time, losing to the Great Falls Dodgers in 2000. After the 2002 season, Toronto ended their affiliation with the club, and the Pioneer League abandoned Medicine Hat.
Over the years, some of the most notable players to wear a Medicine Hat uniform include Lloyd Moseby, Fred Manrique, John Cerutti, Gustavo Chacin, Geronimo Berroa and Jay Gibbons, who won the league's Triple Crown in 1998.