From BR Bullpen
Through December 2010, 57 no-hitters have been thrown in the Cuban Serie Nacional, Series Selectivas or Super Liga. 52 of them have been no-hit, no-run games and one was a perfect game.
| Pitcher | Date | Team | Opponent | Score | Notes
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| Aquino Abreu | January 16, 1966 | Centrales | Occidentales | 11 - 0 |
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| Aquino Abreu | January 25, 1966 | Centrales | Industriales | 7 - 0 | Back-to-back no-hitter; the only such occurrence in Cuban history
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| Manuel Alarcón | January 24, 1967 | Orientales | Las Villas | 2 - 1 |
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| Roberto Valdés | February 14, 1967 | Orientales | Granjeros | 12 - 0 |
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| Leopoldo Valdés | January 7, 1968 | Habana | Pinar del Río | 5 - 0 |
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| Jesús Pérez | January 7, 1968 | Industriales | Vegueros | 5 - 0 | First day with two no-hitters
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| Douglas Sorriba | January 9, 1968 | Granjeros | Henequeneros | 4 - 1 |
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| José Antonio Huelga | January 14, 1968 | Azucareros | Granjeros | 1 - 0 |
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| Douglas Sorriba | January 16, 1968 | Granjeros | Vegueros | 4 - 1 |
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| Orlando Figueredo | January 25, 1968 | Oriente | Azucareros | 1 - 0 |
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| Florentino Alfonso | March 16, 1968 | Granjeros | Camagüey | 0 - 1 | Only loss in a no-hitter
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| Florentino González | April 4, 1968 | Camagüey | Matanzas | 1 - 0 |
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| Raúl Álvarez | December 10, 1968 | Pinar del Río | Camagüey | 9 - 0 | 9th and last no-hitter in the Year of the Pitcher
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| Andrés Liaño | February 4, 1969 | Industriales | Pinar del Río | 8 - 0 |
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| Yoire Fombona | February 4, 1969 | Camagüey | Oriente | 6 - 1 | Second day with two no-hitters
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| Alfredo García | April 6, 1969 | Henequeneros | Azucareros | 1 - 0 |
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| Rigoberto Betancourt | January 7, 1970 | Industriales | Oriente | 1 - 0 |
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| Walfrido Ruiz, Elpidio Paez | January 16, 1971 | Habana | Camagüey | 10 - 0 | First combined no-hitter
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| Aniceto Montes de Oca | January 21, 1971 | Azucareros | Pinar del Río | 5 - 0 |
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| Juan Pérez Pérez | February 22, 1973 | Camagüey | Serranos | 7 - 0 |
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| Juan Pérez Pérez | April 25, 1974 | Camagüey | Oriente | 1 - 0 |
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| Juan Pérez Pérez | January 19, 1975 | Ganaderos | Citricultores | 2 - 0 | Only pitcher with three no-hitters
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| Oscar Romero | May 4, 1975 | Camagüeyanos | Industriales | 4 - 0 | First Series Selectivas no-hitter
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| Porfirio Pérez | December 27, 1977 | Forestales | Habana | 3 - 0 |
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| Juan R. Gómez, Pablo Castro, José Brizuela | February 18, 1979 | Ganaderos | Ciego de Ávila | 14 - 0 | Only three-pitcher no-hitter
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| Nivaldo Pérez | March 28, 1979 | Las Villas | Camagüeyanos | 4 - 0 |
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| Omar Carrero | January 27, 1981 | Ciego de Ávila | Las Tunas | 13 - 0 |
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| Ángel Leocadio Díaz | January 16, 1982 | Industriales | Holguín | 2 - 0 |
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| Carlos Mesa | February 11, 1982 | Citricultores | Habana | 6 - 0 |
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| José Manuel Pedroso | May 18, 1982 | Habana | Camagüeyanos | 1 - 0 |
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| Mario Véliz | December 30, 1982 | Villa Clara | Citricultores | 3 - 0 |
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| Julio Romero | March 9, 1983 | Pinar del Río | Camagüeyanos | 2 - 0 |
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| Jorge Luis Valdés | January 31, 1984 | Henequeneros | Villa Clara | 1 - 0 | Finals
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| Rogelio García | March 1, 1987 | Pinar del Río | Camagüeyanos | 10 - 0 |
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| Rogelio García | March 22, 1987 | Pinar del Río | Serranos | 3 - 0 |
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| Osvaldo Fernández Guerra | December 10, 1988 | Metropolitanos | Citricultores | 6 - 0 |
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| Héctor Domínguez | December 13, 1989 | Citricultores | Isla de la Juventud | 2 - 0 |
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| Orlando Hernández | April 7, 1990 | Habana | Matanzas | 11 - 0 |
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| Faustino Corrales | November 19, 1991 | Vegueros | Isla de la Juventud | 7 - 0 |
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| Osvaldo Fernández Rodríguez | November 29, 1992 | Holguín | Metropolitanos | 10 - 0 |
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| Ernesto Guevara | December 8, 1992 | Granma | Industriales | 2 - 0 |
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| Modesto Luis | November 18, 1997 | Las Tunas | Granma | 7 - 0 |
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| Geovanis Castañeda | November 22, 1997 | Guantánamo | Las Tunas | 8 - 0 |
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| José Miguel Báez | November 17, 1998 | Las Tunas | Metropolitanos | 6 - 0 |
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| Maels Rodríguez | December 22, 1999 | Sancti Spíritus | Las Tunas | 1 - 0 | Only perfect game
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| Adiel Palma | December 25, 1999 | Cienfuegos | Las Tunas | 4 - 0 |
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| Carlos A. Yanes | March 5, 2000 | Isla de la Juventud | Villa Clara | 6 - 0 |
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| Norge Luis Vera | January 21, 2001 | Santiago de Cuba | La Habana | 3 - 0 |
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| Michel Pérez | February 7, 2001 | Villa Clara | Las Tunas | 10 - 0 |
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| Maels Rodríguez | August 21, 2002 | Centrales | Habaneros | 1 - 0 | Only no-hitter in the Súper Liga
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| Fernando Tejeda | January 22, 2004 | Camagüey | Industriales | 1 - 0 |
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| José A. Barroso | February 12, 2005 | Ciego de Ávila | Cienfuegos | 10 - 0 |
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| Damichel González | March 5, 2005 | Las Tunas | Camagüey | 4 - 0 |
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| Jonder Martínez | March 6, 2008 | La Habana | Ciego de Ávila | 7 - 0 |
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| Jorge Martínez Roque | January 29, 2009 | Matanzas | Camagüey | 3 - 0 |
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| Vladimir Baños | December 23, 2010 | Pinar del Río | Matanzas | 5 - 0 |
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| Raimar Navarro, Pablo Fernández | March 13, 2012 | Holguín | Camagüey | 1 - 0 (10 Inn.) | First extra-inning no-hitter in Cuba; First no-hitter in a game involving the Schiller Rule
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