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2005 Amateur Draft
From BR Bullpen
First pick Upton is the brother of of B.J. Upton who had been selected with the second overall pick in 2002 by the Tampa Bay Devil Rays. Golden Spikes Award winner Alex Gordon of the University of Nebraska was drafted with the number two selection by the Kansas City Royals. Wade Townsend, who had been drafted the previous year by the Baltimore Orioles but could not reach a contract agreement, was drafted by Tampa Bay.
Collegiate players accounted for two-thirds of the first round selections and all but the first and tenth of the top ten picks. 13 pitchers were selected in the first round.
 2005 First Round Picks
 Supplemental First Round
 Other Notable Selections
 Draft Notes
- Townsend did not play on the school's team in 2005.