| Pick
| Team
| Player
| Position
| School (Type)
| Hometown
| Notes
|
| 1 | Washington Senators | Jeff Burroughs | OF | Wilson High School (Long Beach) (HS) | Long Beach, CA |
|
| 2 | Houston Astros | J.R. Richard | RHP | Lincoln High School (HS) | Ruston, LA |
|
| 3 | Chicago White Sox | Ted Nicholson | 3B | Oak Park High School (HS) | Laurel, MS |
|
| 4 | New York Mets | Randy Sterling | RHP | Key West High School (HS) | Key West, FL |
|
| 5 | California Angels | Alan Bannister | SS | Kennedy High School (HS) | Buena Park, CA | Did not sign
|
| 6 | Philadelphia Phillies | Mike Anderson | 1B | Timmonsville High School (HS) | Timmonsville, SC |
|
| 7 | Minnesota Twins | Paul Ray Powell | OF | Arizona State University (Col.) | San Angelo, TX |
|
| 8 | Los Angeles Dodgers | Terry McDermott | C | St. Agnes High School (HS) | West Hempstead, NY |
|
| 9 | Oakland Athletics | Don Stanhouse | RHP-SS | DuQuoin High School (HS) | DuQuoin, IL |
|
| 10 | Pittsburgh Pirates | Bob May | RHP | Merritt Island High School (HS) | Merritt Island, FL |
|
| 11 | New York Yankees | Charlie Spikes | 3B-OF | Central Memorial High School (HS) | Bogalusa, LA |
|
| 12 | Atlanta Braves | Gene Holbert | C | Palmyra High School (HS) | Campbelltown, PA |
|
| 13 | Boston Red Sox | Noel Jenke | OF | University of Minnesota (Col.) | Owatonna, MN |
|
| 14 | Cincinnati Reds | Don Gullett | LHP | McKell High School (HS) | Lynn, KY |
|
| 15 | Cleveland Indians | Alvin McGrew | OF | Parker High School (HS) | Fairfield, AL |
|
| 16 | Chicago Cubs | Roger Metzger | SS | St. Edward's University (Col.) | Fredericksburg, TX |
|
| 17 | Baltimore Orioles | Don Hood | LHP | Southside High School (HS) | Florence, SC |
|
| 18 | San Francisco Giants | Mike Phillips | SS | MacArthur High School (HS) | Irving, TX |
|
| 19 | Detroit Tigers | Lenny Baxley | 1B | Enterprise High School (HS) | Redding, CA |
|
| 20 | St. Louis Cardinals | Charles Minott | LHP | Royal Oak High School (HS) | Covina, CA |
|
| 21 | Seattle Pilots | Gorman Thomas | SS | James Island High School (HS) | Charleston, SC |
|
| 22 | Montreal Expos | Balor Moore | LHP | Deer Park High School (HS) | Deer Park, TX |
|
| 23 | Kansas City Royals | John Simmons (minors) | SS | Childersburg High School (HS) | Childersburg, AL | Did not sign
|
| 24 | San Diego Padres | Randy Elliott | 1B | Camarillo High School (HS) | Camarillo, CA |
|
