The 1949 season of the All-American Girls Professional Baseball League was the seventh season of the league.
 Season Summary
- Italics indicates a playoff team, Bold indicates the Shaughnessy Series champion
- Bold indicates league record
 All-Star Game
The league's seventh All-Star Game was played on at . by a score of .
The playoffs featured the top six teams in the league. The first and second place teams received byes to the semi-finals while the second through sixth place teams competed in a best-of-three first round. In it the third place team faced off against the fifth place team and the fourth place team played against the sixth place team. The winners then advanced to the best-of-five semi-finals, with the first place team taking on the winner of the third-fifth place series while the second place team played against the winner of the fourth-sixth place series. The semi-final winners then met in the best-of-seven Shaughnessy Series.
 Award Winners
The winner of the league's Player of the Year Award, was Doris Sams, an outfielder/pitcher with the Muskegon Lassies. The award was voted upon by the league's managers.
 All-Star Team
The following players were named to the league's all-star team, as voted upon by the league's managers.
 Notable Events