MLB Scores and Standings Saturday, May 16, 1981
| St. Louis Cardinals | 6 | Final |
| Atlanta Braves | 2 |
| W | Silvio Martínez (1-2) |
| L | Tommy Boggs (1-6) |
| S | Bruce Sutter (7) |
| Kansas City Royals | 7 | Final |
| Boston Red Sox | 6 |
| W | Larry Gura (4-3) |
| L | Dennis Eckersley (3-3) |
| S | Dan Quisenberry (2) |
| Texas Rangers | 1 | Final |
| Chicago White Sox | 9 |
| W | Britt Burns (3-2) |
| L | Danny Darwin (4-3) |
| Toronto Blue Jays | 4 | Final |
| Cleveland Indians | 1 |
| W | Jackson Todd (2-3) |
| L | Wayne Garland (2-3) |
| California Angels | 5 | Final |
| Detroit Tigers | 7 |
| W | Dave Tobik (1-0) |
| L | Doug Rau (0-1) |
| S | Kevin Saucier (3) |
| Chicago Cubs | 1 | Final |
| Houston Astros | 6 |
| W | Nolan Ryan (3-1) |
| L | Randy Martz (1-2) |
| S | Joe Sambito (2) |
| New York Mets | 0 | Final |
| Los Angeles Dodgers | 9 |
| W | Burt Hooton (6-0) |
| L | Dave Roberts (0-3) |
| Oakland Athletics | 5 | Final |
| Milwaukee Brewers | 6 |
| W | Reggie Cleveland (2-0) |
| L | Bob Owchinko (1-1) |
| S | Rollie Fingers (6) |
| Baltimore Orioles | 7 | Final |
| Minnesota Twins | 0 |
| W | Dave Ford (1-0) |
| L | Jerry Koosman (1-6) |
| Seattle Mariners | 5 | Final |
| New York Yankees | 7 |
| W | Doug Bird (2-0) |
| L | Jerry Don Gleaton (2-6) |
| S | Rich Gossage (10) |
| Cincinnati Reds | 4 | Final |
| Pittsburgh Pirates | 0 |
| W | Mike LaCoss (2-4) |
| L | Rod Scurry (1-2) |
| Philadelphia Phillies | 1 | Final |
| San Diego Padres | 2 |
| W | John Littlefield (1-2) |
| L | Tug McGraw (1-3) |
| Montreal Expos | 5 | Final |
| San Francisco Giants | 0 |
| W | Charlie Lea (2-1) |
| L | Tom Griffin (3-3) |
Standings Up to and Including this Date
AL East Division
AL West Division
NL East Division
AL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| OAK | 25 | 11 | .694 | -- | 163 | 107 | .684 |
| CLE | 16 | 9 | .640 | 3.5 | 88 | 77 | .561 |
| BAL | 18 | 11 | .621 | 3.5 | 130 | 104 | .601 |
| NYY | 19 | 13 | .594 | 4.0 | 126 | 103 | .591 |
| TEX | 18 | 13 | .581 | 4.5 | 153 | 118 | .617 |
| CHW | 16 | 14 | .533 | 6.0 | 132 | 116 | .559 |
| BOS | 16 | 15 | .516 | 6.5 | 142 | 162 | .440 |
| MIL | 16 | 15 | .516 | 6.5 | 136 | 127 | .531 |
| CAL | 18 | 18 | .500 | 7.0 | 156 | 145 | .533 |
| DET | 16 | 16 | .500 | 7.0 | 108 | 121 | .448 |
| MIN | 11 | 21 | .344 | 12.0 | 119 | 145 | .411 |
| KCR | 8 | 18 | .308 | 12.0 | 76 | 119 | .306 |
| TOR | 11 | 22 | .333 | 12.5 | 109 | 142 | .381 |
| SEA | 10 | 22 | .313 | 13.0 | 121 | 173 | .342 |
NL Overall
| Tm | W | L | GB | RS | RA | pythW-L% | |
|---|---|---|---|---|---|---|---|
| LAD | 25 | 9 | .735 | -- | 137 | 85 | .705 |
| STL | 18 | 9 | .667 | 3.5 | 137 | 108 | .607 |
| PHI | 20 | 13 | .606 | 4.5 | 146 | 131 | .549 |
| CIN | 19 | 14 | .576 | 5.5 | 144 | 126 | .561 |
| MON | 18 | 14 | .563 | 6.0 | 132 | 138 | .480 |
| ATL | 18 | 15 | .545 | 6.5 | 140 | 124 | .555 |
| HOU | 17 | 18 | .486 | 8.5 | 111 | 97 | .561 |
| SFG | 18 | 19 | .486 | 8.5 | 129 | 129 | .500 |
| PIT | 12 | 15 | .444 | 9.5 | 106 | 103 | .513 |
| SDP | 14 | 21 | .400 | 11.5 | 120 | 149 | .402 |
| NYM | 8 | 21 | .276 | 14.5 | 93 | 143 | .313 |
| CHC | 5 | 24 | .172 | 17.5 | 79 | 141 | .257 |
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