MLB Scores and Standings Sunday, May 16, 1965
| New York Yankees | 5 | Final |
| Baltimore Orioles | 7 |
| W | Jim Palmer (1-0) |
| L | Pete Mikkelsen (0-1) |
| S | Stu Miller (2) |
| Detroit Tigers | 0 | Final |
| Boston Red Sox | 5 |
| W | Earl Wilson (3-2) |
| L | Dave Wickersham (1-2) |
| Detroit Tigers | 3 | Final |
| Boston Red Sox | 4 |
| W | Bill Monbouquette (5-2) |
| L | Joe Sparma (1-2) |
| S | Dick Radatz (5) |
| California Angels | 2 | Final |
| Chicago White Sox | 6 |
| W | John Buzhardt (4-0) |
| L | Rudy May (2-2) |
| S | Eddie Fisher (8) |
| California Angels | 4 | Final |
| Chicago White Sox | 5 |
| W | Tommy John (3-0) |
| L | George Brunet (1-2) |
| S | Eddie Fisher (9) |
| Minnesota Twins | 4 | Final |
| Kansas City Athletics | 7 | (10) |
| W | John Wyatt (1-0) |
| L | Mel Nelson (0-1) |
| Minnesota Twins | 2 | Final |
| Kansas City Athletics | 4 |
| W | Moe Drabowsky (1-3) |
| L | Johnny Klippstein (1-1) |
| S | Wes Stock (2) |
| Chicago Cubs | 5 | Final |
| Los Angeles Dodgers | 3 | (10) |
| W | Larry Jackson (3-3) |
| L | Ron Perranoski (0-1) |
| Chicago Cubs | 2 | Final |
| Los Angeles Dodgers | 3 |
| W | Don Drysdale (6-2) |
| L | Lindy McDaniel (0-1) |
| Cincinnati Reds | 2 | Final |
| New York Mets | 6 |
| W | Jack Fisher (3-3) |
| L | John Tsitouris (3-3) |
| S | Dennis Ribant (3) |
| Cincinnati Reds | 5 | Final |
| New York Mets | 8 |
| W | Warren Spahn (3-3) |
| L | Sammy Ellis (5-1) |
| S | Frank Lary (1) |
| Milwaukee Braves | 8 | Final |
| Philadelphia Phillies | 6 | (10) |
| W | Billy O'Dell (2-2) |
| L | Jack Baldschun (3-1) |
| S | Wade Blasingame (1) |
| St. Louis Cardinals | 6 | Final |
| Pittsburgh Pirates | 3 |
| W | Bob Gibson (7-0) |
| L | Don Cardwell (1-2) |
| St. Louis Cardinals | 5 | Final |
| Pittsburgh Pirates | 1 |
| W | Ray Washburn (3-1) |
| L | Bob Veale (2-2) |
| S | Bob Purkey (2) |
| Houston Astros | 5 | Final |
| San Francisco Giants | 10 |
| W | Juan Marichal (6-3) |
| L | Dave Giusti (6-1) |
| Houston Astros | 3 | Final |
| San Francisco Giants | 4 |
| W | Bob Shaw (2-1) |
| L | Don Nottebart (0-3) |
| S | Masanori Murakami (1) |
| Cleveland Indians | 7 | Final |
| Washington Senators | 8 | (11) |
| W | Phil Ortega (3-4) |
| L | Dick Donovan (1-2) |
| Cleveland Indians | 7 | Final |
| Washington Senators | 3 |
| W | Luis Tiant (2-2) |
| L | Frank Kreutzer (0-3) |
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